ID   A0A269PU02_9GAMM        Unreviewed;      1027 AA.
AC   A0A269PU02;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   24-JAN-2024, entry version 15.
DE   RecName: Full=Acriflavin resistance protein {ECO:0008006|Google:ProtNLM};
GN   ORFNames=CJF42_02855 {ECO:0000313|EMBL:PAJ75800.1};
OS   Pseudoalteromonas sp. NBT06-2.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Alteromonadales;
OC   Pseudoalteromonadaceae; Pseudoalteromonas.
OX   NCBI_TaxID=2025950 {ECO:0000313|EMBL:PAJ75800.1, ECO:0000313|Proteomes:UP000215836};
RN   [1] {ECO:0000313|EMBL:PAJ75800.1, ECO:0000313|Proteomes:UP000215836}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NBT06-2 {ECO:0000313|EMBL:PAJ75800.1,
RC   ECO:0000313|Proteomes:UP000215836};
RA   Wei Y.;
RT   "Pseudoalteromonas hadalis sp. nov., a facultative psychrophile isolated
RT   from New Britain Trench.";
RL   Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:PAJ75800.1}.
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DR   EMBL; NQMR01000007; PAJ75800.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A269PU02; -.
DR   OrthoDB; 5287122at2; -.
DR   Proteomes; UP000215836; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0022857; F:transmembrane transporter activity; IEA:InterPro.
DR   Gene3D; 3.30.70.1430; Multidrug efflux transporter AcrB pore domain; 2.
DR   Gene3D; 3.30.70.1440; Multidrug efflux transporter AcrB pore domain; 1.
DR   Gene3D; 3.30.70.1320; Multidrug efflux transporter AcrB pore domain like; 1.
DR   Gene3D; 1.20.1640.10; Multidrug efflux transporter AcrB transmembrane domain; 2.
DR   InterPro; IPR027463; AcrB_DN_DC_subdom.
DR   InterPro; IPR001036; Acrflvin-R.
DR   PANTHER; PTHR32063; -; 1.
DR   PANTHER; PTHR32063:SF73; RND SUPERFAMILY EFFLUX PUMP PERMEASE COMPONENT 1; 1.
DR   Pfam; PF00873; ACR_tran; 2.
DR   PRINTS; PR00702; ACRIFLAVINRP.
DR   SUPFAM; SSF82866; Multidrug efflux transporter AcrB transmembrane domain; 2.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000215836};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        348..367
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        374..394
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        400..425
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        445..464
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        470..493
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        535..554
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        850..869
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        876..898
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        904..923
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        951..969
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        975..1003
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
SQ   SEQUENCE   1027 AA;  114049 MW;  E466DD677AB9D232 CRC64;
     MMLIMIVDQK NKKFGLPINL WLTSLALKRP VTTVMVMLSL FVTGLVASRL LPQESWPSVT
     VPVVFIYVPY SGSSPKEVER LITRPIEEAI ATVGGISSMK SRSRANSSGI QIMMDLGSDL
     DSKILEIREK VDMISHLLPD DVQKVNVQKF STDDFPIMTL TISGEKDLSH AYDFLNKKLV
     RKIERLIGVG KIELRGVVKP NIEIKLDSTK LAMNRVNQGQ LLKNLRESNF IVRSASILNG
     ERKFSVTSQG EYKSLADINN FQVKANIKLS DVAQVSLKSP EKDSEIRSDR QKTIGLEIFK
     ESDANVVDVA NNVVNFVDII AADPEFKHIK IKVKNNSGNE IQESLSDLLK AGFVGIVLSF
     SVLYIFFRNY RVTLAVVASV PVSLSFAIAG MYFMGYTLNM LTLAGLFIAV GLLIDNSVVI
     CESILQQQSN GLTHYQKVIK GVDNVSIAVI CGTLTTVIIF LPILMGEKNF ITVLIEQIAV
     AICLPLLASL LVAKTLIPLM LSKVTQNELA QVTTQSWIDA FYRPSLKKIL LNPKYSALGV
     LLLCLLGFFA RDFVSNQQEH SKKSKDITIR YHVISGQKLA DVSQLVDQME AYLYDNQEEF
     GFKKVDSRIY ADYASSRIKL NKHLPMPISE LKEKIRAGFP KTAIAKPSFA WSDNKEMFAS
     ISLLGSSTER LMSLSESVIL RLKQIEGFDE VGIDDTDKKL ELLLRIDNEK VARLGLNTQD
     IANRISTALR GVNLRSFRDE AVGEIEMRLV YHDKKALPLS QIKDLPIYET QGRILTLQQL
     VTFDSQPVLP IIHRVQRQTS LTISINLNDI TRTKAAEKIK VAMKGIALPT GYEWQLGKAY
     RNDDISMANM TINMLLALAL IFMVMAALFE SLLMPIAILS SIALAFIGVY FTFTIMNMGL
     GETAMIGMLI LMGIVVNNGI VLIDQINKLK GSSTSLTEPI IDACATRIRP ILMTVATTII
     GLVPVAIASS NNEAYPLAIA IIGGLIFSTF TSLFLVPYCY LMLVKLGERS AKRFTLAKKF
     ADKYIET
//