ID A0A269WBF2_9BACL Unreviewed; 637 AA.
AC A0A269WBF2;
DT 20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT 20-DEC-2017, sequence version 1.
DT 27-MAR-2024, entry version 22.
DE RecName: Full=DNA helicase {ECO:0000256|ARBA:ARBA00012551};
DE EC=3.6.4.12 {ECO:0000256|ARBA:ARBA00012551};
GN ORFNames=CHH75_04410 {ECO:0000313|EMBL:PAK55484.1};
OS Paenibacillus sp. 7541.
OC Bacteria; Bacillota; Bacilli; Bacillales; Paenibacillaceae; Paenibacillus.
OX NCBI_TaxID=2026236 {ECO:0000313|EMBL:PAK55484.1, ECO:0000313|Proteomes:UP000215741};
RN [1] {ECO:0000313|EMBL:PAK55484.1, ECO:0000313|Proteomes:UP000215741}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=7541 {ECO:0000313|EMBL:PAK55484.1,
RC ECO:0000313|Proteomes:UP000215741};
RA Kalinowski J., Ahrens B., Al-Dilaimi A., Winkler A., Wibberg D.,
RA Schleenbecker U., Ruckert C., Wolfel R., Grass G.;
RT "Isolation and whole genome analysis of endospore-forming bacteria from
RT heroin.";
RL Submitted (AUG-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.12;
CC Evidence={ECO:0000256|ARBA:ARBA00001665};
CC -!- SIMILARITY: Belongs to the helicase family. RAD25/XPB subfamily.
CC {ECO:0000256|ARBA:ARBA00006637}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAK55484.1}.
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DR EMBL; NQLZ01000005; PAK55484.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A269WBF2; -.
DR Proteomes; UP000215741; Unassembled WGS sequence.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR GO; GO:0004386; F:helicase activity; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:InterPro.
DR CDD; cd18789; SF2_C_XPB; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR032438; ERCC3_RAD25_C.
DR InterPro; IPR006935; Helicase/UvrB_N.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR032830; XPB/Ssl2_N.
DR PANTHER; PTHR11274:SF0; GENERAL TRANSCRIPTION AND DNA REPAIR FACTOR IIH HELICASE SUBUNIT XPB; 1.
DR PANTHER; PTHR11274; RAD25/XP-B DNA REPAIR HELICASE; 1.
DR Pfam; PF16203; ERCC3_RAD25_C; 1.
DR Pfam; PF13625; Helicase_C_3; 1.
DR Pfam; PF04851; ResIII; 1.
DR PRINTS; PR00851; XRODRMPGMNTB.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000313|EMBL:PAK55484.1};
KW Helicase {ECO:0000313|EMBL:PAK55484.1};
KW Hydrolase {ECO:0000313|EMBL:PAK55484.1};
KW Nucleotide-binding {ECO:0000313|EMBL:PAK55484.1};
KW Reference proteome {ECO:0000313|Proteomes:UP000215741}.
FT DOMAIN 259..415
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 466..618
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 176..235
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 181..195
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 196..221
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 637 AA; 70754 MW; 14F141C764F3C040 CRC64;
MEQKPCIVQR DRTVLLETAH PSFQKARAEL AQYADLVKSP AAYHTYRITP LSLWNAAAAG
LTADHICISL RSLSRWELPA ALEEDIRRLV ARYGQLTLKM HPARDGRLLL QSRSASVLAE
LKGYPSLASS GLVILSELEA EAPSRLRGLL KQELTRLGYP VLDHVGYQDG QFLPLDWRDG
DRSASGQREP ERQEPLSEQT GTPRAISAAA SAQSSGQKGR SAEQEGAERV DGIPAGSVAA
PKGSFRLRDY QRAAVDAFKE SGGEGGSGVL VLPCGAGKTI IGLAAMRELQ CETLILTSNA
TSVTQWISEL LDKTTLLPEQ IGEYTAEHKA VRPVTVATYQ ILTHRHRKEE EQFHMKLFNE
RRWGLIIYDE VHLLPAPVFR ATADIQATRR LGLTATLVRE DGREADVFSL IGPKRYEMPW
KALEEQGWIA AVRCIEVKVP LPGPIKERCR YSGKREQYRL AAENPAKLEL IKALVRRHPG
AQILIIGQYL NQLTAIAEQL QVPLISGQMP QQRRHELYAS FRRGETPVLV VSKVANFAVD
LPDASVAIEV SGTFGSRQEE AQRLGRILRP KSGENRAYFY TLVSSDSREE MFAMRRQLFL
VEQGYVYEAM SIPLAEEQGR KPGQIGAAAE REVSGQR
//
