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Database: UniProt
Entry: A0A270PLE7_9PSED
LinkDB: A0A270PLE7_9PSED
Original site: A0A270PLE7_9PSED 
ID   A0A270PLE7_9PSED        Unreviewed;       503 AA.
AC   A0A270PLE7;
DT   20-DEC-2017, integrated into UniProtKB/TrEMBL.
DT   20-DEC-2017, sequence version 1.
DT   16-JAN-2019, entry version 9.
DE   RecName: Full=Chromosomal replication initiator protein DnaA {ECO:0000256|HAMAP-Rule:MF_00377, ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01081161};
GN   Name=dnaA {ECO:0000256|HAMAP-Rule:MF_00377};
GN   ORFNames=CES87_00595 {ECO:0000313|EMBL:PAM85041.1};
OS   Pseudomonas sp. ERMR1:02.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=1805930 {ECO:0000313|EMBL:PAM85041.1, ECO:0000313|Proteomes:UP000215719};
RN   [1] {ECO:0000313|EMBL:PAM85041.1, ECO:0000313|Proteomes:UP000215719}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ERMR1:02 {ECO:0000313|EMBL:PAM85041.1,
RC   ECO:0000313|Proteomes:UP000215719};
RA   Kumar R., Acharya V., Singh D., Kumar S.;
RT   "Pseudomonas sp. ERMR1:02, Genome sequencing and assembly.";
RL   Submitted (JUN-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Plays an important role in the initiation and regulation
CC       of chromosomal replication. Binds to the origin of replication; it
CC       binds specifically double-stranded DNA at a 9 bp consensus (dnaA
CC       box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic
CC       phospholipids. {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756121}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
CC       ECO:0000256|SAAS:SAAS01082709}.
CC   -!- SIMILARITY: Belongs to the DnaA family. {ECO:0000256|HAMAP-
CC       Rule:MF_00377, ECO:0000256|RuleBase:RU004227,
CC       ECO:0000256|SAAS:SAAS00555179}.
CC   -!- CAUTION: The sequence shown here is derived from an
CC       EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is
CC       preliminary data. {ECO:0000313|EMBL:PAM85041.1}.
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DR   EMBL; NKJI01000001; PAM85041.1; -; Genomic_DNA.
DR   Proteomes; UP000215719; Unassembled WGS sequence.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0003688; F:DNA replication origin binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0006270; P:DNA replication initiation; IEA:UniProtKB-UniRule.
DR   GO; GO:0006275; P:regulation of DNA replication; IEA:UniProtKB-UniRule.
DR   CDD; cd06571; Bac_DnaA_C; 1.
DR   Gene3D; 1.10.1750.10; -; 1.
DR   Gene3D; 3.30.300.180; -; 1.
DR   HAMAP; MF_00377; DnaA_bact; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR001957; Chromosome_initiator_DnaA.
DR   InterPro; IPR020591; Chromosome_initiator_DnaA-like.
DR   InterPro; IPR018312; Chromosome_initiator_DnaA_CS.
DR   InterPro; IPR013317; DnaA.
DR   InterPro; IPR013159; DnaA_C.
DR   InterPro; IPR024633; DnaA_N_dom.
DR   InterPro; IPR038454; DnaA_N_sf.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR010921; Trp_repressor/repl_initiator.
DR   PANTHER; PTHR30050:SF2; PTHR30050:SF2; 1.
DR   Pfam; PF00308; Bac_DnaA; 1.
DR   Pfam; PF08299; Bac_DnaA_C; 1.
DR   Pfam; PF11638; DnaA_N; 1.
DR   PRINTS; PR00051; DNAA.
DR   SMART; SM00382; AAA; 1.
DR   SMART; SM00760; Bac_DnaA_C; 1.
DR   SUPFAM; SSF48295; SSF48295; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   TIGRFAMs; TIGR00362; DnaA; 1.
DR   PROSITE; PS01008; DNAA; 1.
PE   3: Inferred from homology;
KW   ATP-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756129};
KW   Complete proteome {ECO:0000313|Proteomes:UP000215719};
KW   Cytoplasm {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|SAAS:SAAS01082702};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU004227, ECO:0000256|SAAS:SAAS00756116};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS01082706};
KW   Nucleotide-binding {ECO:0000256|HAMAP-Rule:MF_00377,
KW   ECO:0000256|RuleBase:RU000577, ECO:0000256|SAAS:SAAS00756117}.
FT   DOMAIN      200    405       AAA. {ECO:0000259|SMART:SM00382}.
FT   DOMAIN      411    480       Bac_DnaA_C. {ECO:0000259|SMART:SM00760}.
FT   NP_BIND     208    215       ATP. {ECO:0000256|HAMAP-Rule:MF_00377}.
SQ   SEQUENCE   503 AA;  56575 MW;  76AFEA39CF63CB07 CRC64;
     MSVELWQQCV ELLRDELPAQ QFNTWIRPLQ VEAEGDELRV YAPNRFVLDW VNEKYLGRVL
     ELLDEHGNGM APALSLLIGS KRSSAPRAAP NAPLAAAAAA SQVQVASAQA PAATPTKRAT
     QKVAEVVEQE PSRDSFDPMA GASSQQAPVR AEQRTVQVEG ALKHTSYLNR TFTFENFVEG
     KSNQLARAAA WQVADNPKHG YNPLFLYGGV GLGKTHLMHA VGNHLLKKNP NAKVVYLHSE
     RFVADMVKAL QLNAINEFKR FYRSVDALLI DDIQFFARKE RSQEEFFHTF NALLEGGQQV
     ILTSDRYPKE IEGLEERLKS RFGWGLTVAV EPPELETRVA ILMKKADQAK VELPHDAAFF
     IAQRIRSNVR ELEGALKRVI AHSHFMGRDI TIELIRESLK DLLALQDKLV SVDNIQRTVA
     EYYKIKISDL LSKRRSRSVA RPRQVAMALS KELTNHSLPE IGDVFGGRDH TTVLHACRKI
     NELKESDADI REDYKNLLRT LTT
//
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