ID A0A285GR57_9ACTN Unreviewed; 429 AA.
AC A0A285GR57;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Na+/H+ antiporter NhaD {ECO:0000313|EMBL:SNY25724.1};
GN ORFNames=SAMN05421748_102398 {ECO:0000313|EMBL:SNY25724.1};
OS Actinoplanes atraurantiacus.
OC Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC Micromonosporaceae; Actinoplanes.
OX NCBI_TaxID=1036182 {ECO:0000313|EMBL:SNY25724.1, ECO:0000313|Proteomes:UP000219612};
RN [1] {ECO:0000313|EMBL:SNY25724.1, ECO:0000313|Proteomes:UP000219612}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.6857 {ECO:0000313|EMBL:SNY25724.1,
RC ECO:0000313|Proteomes:UP000219612};
RA Ehlers B., Leendertz F.H.;
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000256|ARBA:ARBA00004651};
CC Multi-pass membrane protein {ECO:0000256|ARBA:ARBA00004651}. Membrane
CC {ECO:0000256|ARBA:ARBA00004141}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141}.
CC -!- SIMILARITY: Belongs to the CitM (TC 2.A.11) transporter family.
CC {ECO:0000256|ARBA:ARBA00009843}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; OBDY01000002; SNY25724.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A285GR57; -.
DR OrthoDB; 9809303at2; -.
DR Proteomes; UP000219612; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0015105; F:arsenite transmembrane transporter activity; IEA:InterPro.
DR CDD; cd01116; P_permease; 1.
DR InterPro; IPR000802; Arsenical_pump_ArsB.
DR InterPro; IPR004680; Cit_transptr-like_dom.
DR PANTHER; PTHR43568; P PROTEIN; 1.
DR PANTHER; PTHR43568:SF1; P PROTEIN; 1.
DR Pfam; PF03600; CitMHS; 1.
DR PRINTS; PR00758; ARSENICPUMP.
PE 3: Inferred from homology;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000219612};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}; Transport {ECO:0000256|ARBA:ARBA00022448}.
FT TRANSMEM 6..21
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 28..50
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 56..74
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 95..113
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 176..199
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 227..248
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..271
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 283..302
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 317..335
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 408..426
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 16..371
FT /note="Citrate transporter-like"
FT /evidence="ECO:0000259|Pfam:PF03600"
SQ SEQUENCE 429 AA; 45214 MW; 5B443F1A91E77BD1 CRC64;
MSTIAWVAVV VFAGAYVLIA TEKINRVAVA LGGAAIMLAL GATDAEHAFF SEDAGIDWNV
IFLLLGMMLI VGVLKRTGLF EFVAIWSAKK ARARPFPIMV ILVVVTGVVS AALDNVTTVL
LVAPVTLLVC DRLGVPPIPF LIAEVFASNI GGAGTLVGDP PNIIIASRSG LTFNEFLSVL
APFVLIVLVV LLALCRIMFR TAFRYDAERA AKVMALRERD AIRDPRLAVL SLSVLGAVLV
AFTLHTVLGL EPSVVALLGG LLLLALSRVD ANEVAREVEW PTLIFFAGLF VMVGALVATG
VIDELAHAAT GAVEGKLWPA TLLLLWASAG LSAIVDNIPY VATMSPIVSE LVDASGGNDH
AQVLWWALAI GADLGGNATA VGASANVVVL GLAQRAGHRI TFWGFTKYGL IVTAISVALA
VPYLWLRFF
//
