ID   A0A285I041_9ACTN        Unreviewed;       345 AA.
AC   A0A285I041;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 17.
DE   SubName: Full=DNA polymerase-1 {ECO:0000313|EMBL:SNY41342.1};
GN   ORFNames=SAMN05421748_106155 {ECO:0000313|EMBL:SNY41342.1};
OS   Actinoplanes atraurantiacus.
OC   Bacteria; Actinomycetota; Actinomycetes; Micromonosporales;
OC   Micromonosporaceae; Actinoplanes.
OX   NCBI_TaxID=1036182 {ECO:0000313|EMBL:SNY41342.1, ECO:0000313|Proteomes:UP000219612};
RN   [1] {ECO:0000313|EMBL:SNY41342.1, ECO:0000313|Proteomes:UP000219612}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.6857 {ECO:0000313|EMBL:SNY41342.1,
RC   ECO:0000313|Proteomes:UP000219612};
RA   Ehlers B., Leendertz F.H.;
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; OBDY01000006; SNY41342.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A285I041; -.
DR   OrthoDB; 9806424at2; -.
DR   Proteomes; UP000219612; Unassembled WGS sequence.
DR   GO; GO:0017108; F:5'-flap endonuclease activity; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0033567; P:DNA replication, Okazaki fragment processing; IEA:InterPro.
DR   CDD; cd09859; PIN_53EXO; 1.
DR   Gene3D; 1.10.150.20; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   Gene3D; 3.40.50.1010; 5'-nuclease; 1.
DR   InterPro; IPR020046; 5-3_exonucl_a-hlix_arch_N.
DR   InterPro; IPR002421; 5-3_exonuclease.
DR   InterPro; IPR036279; 5-3_exonuclease_C_sf.
DR   InterPro; IPR020045; DNA_polI_H3TH.
DR   InterPro; IPR038969; FEN.
DR   InterPro; IPR008918; HhH2.
DR   InterPro; IPR029060; PIN-like_dom_sf.
DR   PANTHER; PTHR42646:SF2; DNA-DIRECTED DNA POLYMERASE; 1.
DR   PANTHER; PTHR42646; FLAP ENDONUCLEASE XNI; 1.
DR   Pfam; PF01367; 5_3_exonuc; 1.
DR   Pfam; PF02739; 5_3_exonuc_N; 1.
DR   SMART; SM00475; 53EXOc; 1.
DR   SMART; SM00279; HhH2; 1.
DR   SUPFAM; SSF47807; 5' to 3' exonuclease, C-terminal subdomain; 1.
DR   SUPFAM; SSF88723; PIN domain-like; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW   Reference proteome {ECO:0000313|Proteomes:UP000219612}.
FT   DOMAIN          12..280
FT                   /note="5'-3' exonuclease"
FT                   /evidence="ECO:0000259|SMART:SM00475"
SQ   SEQUENCE   345 AA;  37286 MW;  DD4F3B5327913281 CRC64;
     MVPAGPRTLF EVPLLLVLDG NSLLHRAYHA GAGDGWVDAD GRPIWALRGL FGYLARAAAH
     LRPDALIVGF DCPSSSARRL TYPAYKAHRP DKAPDLTAQL LEAPSLLRDA GVCTVVHESW
     EADDVLASAA ASARRDGWRS VLMTSDRDAF ALLDEHTSVL RVRNGGFDEA VLVEASGLPD
     LYGVHPWQYR DFAALRGDPS DNLHGVRRFG AATAAKLLAA FGSVEAAWEA GAALVRDAVG
     DHAARHFTDP AAREIVDRNR ELMRMRLDLP IPPLASARLP LSMTVMRKAL RTRGINLGPS
     LWALTGGSPP VVEDGADPIP EVRPWVFRGG LTARRDPTPG QLSLF
//