ID   A0A285KZP1_9NOCA        Unreviewed;       247 AA.
AC   A0A285KZP1;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   SubName: Full=Transcriptional regulator, TetR family {ECO:0000313|EMBL:SNY76816.1};
GN   ORFNames=SAMN04244553_0830 {ECO:0000313|EMBL:SNY76816.1};
OS   Nocardia amikacinitolerans.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=756689 {ECO:0000313|EMBL:SNY76816.1, ECO:0000313|Proteomes:UP000219565};
RN   [1] {ECO:0000313|EMBL:SNY76816.1, ECO:0000313|Proteomes:UP000219565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45537 {ECO:0000313|EMBL:SNY76816.1,
RC   ECO:0000313|Proteomes:UP000219565};
RA   Ehlers B., Leendertz F.H.;
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; OBEG01000001; SNY76816.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A285KZP1; -.
DR   STRING; 1379680.GCA_001612615_00182; -.
DR   OrthoDB; 2570341at2; -.
DR   Proteomes; UP000219565; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0045892; P:negative regulation of DNA-templated transcription; IEA:InterPro.
DR   Gene3D; 1.10.10.60; Homeodomain-like; 1.
DR   Gene3D; 1.10.357.10; Tetracycline Repressor, domain 2; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001647; HTH_TetR.
DR   InterPro; IPR004111; Repressor_TetR_C.
DR   InterPro; IPR036271; Tet_transcr_reg_TetR-rel_C_sf.
DR   PANTHER; PTHR30055; HTH-TYPE TRANSCRIPTIONAL REGULATOR RUTR; 1.
DR   PANTHER; PTHR30055:SF151; HTH-TYPE TRANSCRIPTIONAL REPRESSOR RV1353C; 1.
DR   Pfam; PF02909; TetR_C_1; 1.
DR   Pfam; PF00440; TetR_N; 1.
DR   SUPFAM; SSF46689; Homeodomain-like; 1.
DR   SUPFAM; SSF48498; Tetracyclin repressor-like, C-terminal domain; 1.
DR   PROSITE; PS50977; HTH_TETR_2; 1.
PE   4: Predicted;
KW   DNA-binding {ECO:0000256|PROSITE-ProRule:PRU00335};
KW   Reference proteome {ECO:0000313|Proteomes:UP000219565};
KW   Transcription {ECO:0000256|ARBA:ARBA00023163};
KW   Transcription regulation {ECO:0000256|ARBA:ARBA00023015}.
FT   DOMAIN          33..93
FT                   /note="HTH tetR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50977"
FT   DNA_BIND        56..75
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00335"
SQ   SEQUENCE   247 AA;  27183 MW;  1AEECDB29D18BDAA CRC64;
     MTTTETSGSG DLARTLDLLW DTGHRPSRGP KPTLTLDRIV EAAIRVADAE GLAAVTMRRV
     ATELGTGTMS LYRYLPGKAE LLDLMLDRVQ QPQETAAPPD GWRAMLREYA YEMLEMYRRH
     PWLIQVNQTR PVLGPGALAG MEHLVGGIKP MGLSDPELIS VLVMISGYVW GVARTQMFAE
     EAERTTGMTD AEFWEAQSPA LEKAMATGNY PVMASLSASA FDSSFDHFDF GLERILDGLE
     VFVAKRG
//