ID   A0A285L5M4_9NOCA        Unreviewed;       304 AA.
AC   A0A285L5M4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 18.
DE   SubName: Full=DNA-binding transcriptional regulator, LysR family {ECO:0000313|EMBL:SNY80218.1};
GN   ORFNames=SAMN04244553_1884 {ECO:0000313|EMBL:SNY80218.1};
OS   Nocardia amikacinitolerans.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=756689 {ECO:0000313|EMBL:SNY80218.1, ECO:0000313|Proteomes:UP000219565};
RN   [1] {ECO:0000313|EMBL:SNY80218.1, ECO:0000313|Proteomes:UP000219565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45537 {ECO:0000313|EMBL:SNY80218.1,
RC   ECO:0000313|Proteomes:UP000219565};
RA   Ehlers B., Leendertz F.H.;
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the LysR transcriptional regulatory family.
CC       {ECO:0000256|ARBA:ARBA00009437}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; OBEG01000001; SNY80218.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A285L5M4; -.
DR   OrthoDB; 3176554at2; -.
DR   Proteomes; UP000219565; Unassembled WGS sequence.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   CDD; cd08414; PBP2_LTTR_aromatics_like; 1.
DR   Gene3D; 3.40.190.10; Periplasmic binding protein-like II; 2.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005119; LysR_subst-bd.
DR   InterPro; IPR000847; Tscrpt_reg_HTH_LysR.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR30346:SF0; HCA OPERON TRANSCRIPTIONAL ACTIVATOR HCAR; 1.
DR   PANTHER; PTHR30346; TRANSCRIPTIONAL DUAL REGULATOR HCAR-RELATED; 1.
DR   Pfam; PF00126; HTH_1; 1.
DR   Pfam; PF03466; LysR_substrate; 1.
DR   PRINTS; PR00039; HTHLYSR.
DR   SUPFAM; SSF53850; Periplasmic binding protein-like II; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS50931; HTH_LYSR; 1.
PE   3: Inferred from homology;
KW   Activator {ECO:0000256|ARBA:ARBA00023159};
KW   DNA-binding {ECO:0000313|EMBL:SNY80218.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000219565}.
FT   DOMAIN          1..58
FT                   /note="HTH lysR-type"
FT                   /evidence="ECO:0000259|PROSITE:PS50931"
SQ   SEQUENCE   304 AA;  33041 MW;  01AA8AF09ED126FD CRC64;
     MELRHLMSFL ALAEELHFGR AAQRLHLTQP SLSAQLRKLE KSLGVQLVSR NSHEVKLTPA
     GREFEGQARL IVAQLDRAAE ITKAAAAGHS GSLNVGYNLP ASRHVLPDAL ARMAREHPDV
     TVSLWEKRTG PQLAALNDGT LDVGLVYGHP HTAAFRYRPL LQRIPLVAVV GRTHRWAGRS
     GVRFAELAEQ RCVLFAREQC PAMYDSIFRA AADNRIGLDV AQTADDPGAT AHMVSVRPFV
     GFASLPRAQS MNMGGPDSGA VAVKLLDPVP TLDLFAVWRA EETNPAVGLF LDAIEAPHEQ
     TVPV
//