ID   A0A285L9J2_9NOCA        Unreviewed;       681 AA.
AC   A0A285L9J2;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Alkyl sulfatase BDS1, metallo-beta-lactamase superfamily {ECO:0000313|EMBL:SNY81625.1};
GN   ORFNames=SAMN04244553_3227 {ECO:0000313|EMBL:SNY81625.1};
OS   Nocardia amikacinitolerans.
OC   Bacteria; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae;
OC   Nocardia.
OX   NCBI_TaxID=756689 {ECO:0000313|EMBL:SNY81625.1, ECO:0000313|Proteomes:UP000219565};
RN   [1] {ECO:0000313|EMBL:SNY81625.1, ECO:0000313|Proteomes:UP000219565}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 45537 {ECO:0000313|EMBL:SNY81625.1,
RC   ECO:0000313|Proteomes:UP000219565};
RA   Ehlers B., Leendertz F.H.;
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the metallo-beta-lactamase superfamily. Type III
CC       sulfatase family. {ECO:0000256|ARBA:ARBA00033751}.
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DR   EMBL; OBEG01000003; SNY81625.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A285L9J2; -.
DR   STRING; 1379680.GCA_001612615_04911; -.
DR   OrthoDB; 5240502at2; -.
DR   Proteomes; UP000219565; Unassembled WGS sequence.
DR   GO; GO:0018741; F:linear primary-alkylsulfatase activity; IEA:InterPro.
DR   GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR   GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR   GO; GO:0018909; P:dodecyl sulfate metabolic process; IEA:InterPro.
DR   CDD; cd07710; arylsulfatase_Sdsa1-like_MBL-fold; 1.
DR   Gene3D; 1.25.40.880; Alkyl sulfatase, dimerisation domain; 1.
DR   Gene3D; 3.60.15.30; Metallo-beta-lactamase domain; 1.
DR   Gene3D; 3.30.1050.10; SCP2 sterol-binding domain; 1.
DR   InterPro; IPR038536; Alkyl/aryl-sulf_dimr_sf.
DR   InterPro; IPR029229; Alkyl_sulf_C.
DR   InterPro; IPR029228; Alkyl_sulf_dimr.
DR   InterPro; IPR044097; Bds1/SdsA1_MBL-fold.
DR   InterPro; IPR001279; Metallo-B-lactamas.
DR   InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR   InterPro; IPR036527; SCP2_sterol-bd_dom_sf.
DR   PANTHER; PTHR43223; ALKYL/ARYL-SULFATASE; 1.
DR   PANTHER; PTHR43223:SF1; ALKYL_ARYL-SULFATASE BDS1; 1.
DR   Pfam; PF14864; Alkyl_sulf_C; 1.
DR   Pfam; PF14863; Alkyl_sulf_dimr; 1.
DR   Pfam; PF00753; Lactamase_B; 1.
DR   SMART; SM00849; Lactamase_B; 1.
DR   SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR   SUPFAM; SSF55718; SCP-like; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Reference proteome {ECO:0000313|Proteomes:UP000219565};
KW   Zinc {ECO:0000256|ARBA:ARBA00022833}.
FT   DOMAIN          149..371
FT                   /note="Metallo-beta-lactamase"
FT                   /evidence="ECO:0000259|SMART:SM00849"
SQ   SEQUENCE   681 AA;  74270 MW;  8932A84B161DEAE2 CRC64;
     MVERENGETS GPRVSRRGVF GVGAAALAAA GVGVGLGGCA DDDQVRPSAT PTDPSDHIRA
     ANQRAAETLP FSDTADFADA DRGFVTALEP GTITDDQGKV VWDNDSYGFL REPCPQSAHP
     SLWRHSQLTV KQGLYEIAPG FYQIRGLDLS NMTLVEGDTG VVVIDPLISA ETAAAGLALY
     RAHRGNRPVT GLIYSHSHVD HFGGALGVTT RQDVAEGRCP VLAPVGFLEH AVAENIYAGT
     AMARRAAYMY GAALPRGPKG QIGAGLGQTT SLGTVTLIEP TVDIVRTDQE ETIDGVRMVF
     QLTPGTEAPS EMNFYFPDRR VLCMAENATH TMHNILTLRG ALVRDPHVWS KYLTDSINRY
     GRASDVVFSS HHWPVWGTER IVEFLSAQRD LYGYLNDQTL RLLNKGYVGA EIAELIQLPP
     ELTKTWSTQG YYGSVSHNVK AIYQRYMGWF DGNPAHLWEH PPVESAKRHV EAMGGAKEVL
     KKAQRAYDAG DYRWVAQMVN YVVFADPTDT TAKHLQASAF EQLAYGAENA TWRNFYLSGA
     HELRNGSFGT PIQANSTDLL TAISVEQAFD AMSLRVDGPK AWGLRLVTDW RFRDEADRTH
     RAELRNGVLV HYDRRPDDGL PAPDATIVLT RAALSRAFLA GGDLREAVRS GEIAIEGNAA
     ALAQLPELFD KPDPGFAIVT P
//