ID   A0A285MZ15_9PSED        Unreviewed;       370 AA.
AC   A0A285MZ15;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 18.
DE   RecName: Full=alcohol dehydrogenase {ECO:0000256|ARBA:ARBA00013190};
DE            EC=1.1.1.1 {ECO:0000256|ARBA:ARBA00013190};
GN   ORFNames=SAMN05660463_00060 {ECO:0000313|EMBL:SNZ02338.1};
OS   Pseudomonas sp. URIL14HWK12:I9.
OC   Bacteria; Pseudomonadota; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=1261633 {ECO:0000313|EMBL:SNZ02338.1, ECO:0000313|Proteomes:UP000232228};
RN   [1] {ECO:0000313|EMBL:SNZ02338.1, ECO:0000313|Proteomes:UP000232228}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=URIL14HWK12:I9 {ECO:0000313|EMBL:SNZ02338.1,
RC   ECO:0000313|Proteomes:UP000232228};
RA   Ehlers B., Leendertz F.H.;
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a primary alcohol + NAD(+) = an aldehyde + H(+) + NADH;
CC         Xref=Rhea:RHEA:10736, ChEBI:CHEBI:15378, ChEBI:CHEBI:15734,
CC         ChEBI:CHEBI:17478, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00001146};
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=a secondary alcohol + NAD(+) = a ketone + H(+) + NADH;
CC         Xref=Rhea:RHEA:10740, ChEBI:CHEBI:15378, ChEBI:CHEBI:17087,
CC         ChEBI:CHEBI:35681, ChEBI:CHEBI:57540, ChEBI:CHEBI:57945; EC=1.1.1.1;
CC         Evidence={ECO:0000256|ARBA:ARBA00000781};
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DR   EMBL; OBEM01000001; SNZ02338.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A285MZ15; -.
DR   OrthoDB; 9770544at2; -.
DR   Proteomes; UP000232228; Unassembled WGS sequence.
DR   GO; GO:0051903; F:S-(hydroxymethyl)glutathione dehydrogenase activity; IEA:InterPro.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   GO; GO:0006069; P:ethanol oxidation; IEA:InterPro.
DR   CDD; cd08300; alcohol_DH_class_III; 1.
DR   Gene3D; 3.90.180.10; Medium-chain alcohol dehydrogenases, catalytic domain; 1.
DR   Gene3D; 3.40.50.720; NAD(P)-binding Rossmann-like Domain; 1.
DR   InterPro; IPR013149; ADH-like_C.
DR   InterPro; IPR013154; ADH-like_N.
DR   InterPro; IPR014183; ADH_3.
DR   InterPro; IPR011032; GroES-like_sf.
DR   InterPro; IPR036291; NAD(P)-bd_dom_sf.
DR   NCBIfam; TIGR02818; adh_III_F_hyde; 1.
DR   PANTHER; PTHR43880; ALCOHOL DEHYDROGENASE; 1.
DR   PANTHER; PTHR43880:SF12; ALCOHOL DEHYDROGENASE CLASS-3; 1.
DR   Pfam; PF08240; ADH_N; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   SUPFAM; SSF50129; GroES-like; 2.
DR   SUPFAM; SSF51735; NAD(P)-binding Rossmann-fold domains; 1.
PE   4: Predicted;
KW   Reference proteome {ECO:0000313|Proteomes:UP000232228}.
FT   DOMAIN          29..152
FT                   /note="Alcohol dehydrogenase-like N-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF08240"
FT   DOMAIN          198..330
FT                   /note="Alcohol dehydrogenase-like C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF00107"
SQ   SEQUENCE   370 AA;  39201 MW;  493A3E0C86783799 CRC64;
     MIKSRAAVAF EAKKPLEIVE VDVAMPKAGE VLLRVVASGV CHTDAYTLSG ADPEGIFPSI
     LGHEGGAIVE AVGEGVTSVA VGDHVIPLYT PECRQCKFCL SGKTNLCQAI RATQGKGLMP
     DGTSRFSYKG QTLFHYMGTS TFSEYTVLPE ISVARIQKEA PLEKVCLLGC GVTTGIGAVL
     NTAKVKPGDT VAVFGLGGIG LSAIIGAVKA KASRIIAVDI NPAKFEIARQ LGATDCVNPK
     DYDRPIQEVI VDLTDGGVDF SFECVGVPAL MRAALECCHK GWGESVIIGV AGAGQEISTR
     PFQLVTGRVW RGTAFGGVRG RTELPSYVEM ADKGEIPLDT FITHTMGLED INKAFDLMHE
     GKSIRSVIHF
//