ID A0A285NHZ3_9AQUI Unreviewed; 633 AA.
AC A0A285NHZ3;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 22.
DE RecName: Full=acetate--CoA ligase {ECO:0000256|ARBA:ARBA00013275};
DE EC=6.2.1.1 {ECO:0000256|ARBA:ARBA00013275};
GN ORFNames=SAMN06265182_1405 {ECO:0000313|EMBL:SNZ08878.1};
OS Persephonella hydrogeniphila.
OC Bacteria; Aquificota; Aquificae; Aquificales; Hydrogenothermaceae;
OC Persephonella.
OX NCBI_TaxID=198703 {ECO:0000313|EMBL:SNZ08878.1, ECO:0000313|Proteomes:UP000219036};
RN [1] {ECO:0000313|EMBL:SNZ08878.1, ECO:0000313|Proteomes:UP000219036}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=DSM 15103 {ECO:0000313|EMBL:SNZ08878.1,
RC ECO:0000313|Proteomes:UP000219036};
RA Ehlers B., Leendertz F.H.;
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; OBEI01000006; SNZ08878.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A285NHZ3; -.
DR OrthoDB; 9778383at2; -.
DR Proteomes; UP000219036; Unassembled WGS sequence.
DR GO; GO:0003987; F:acetate-CoA ligase activity; IEA:InterPro.
DR GO; GO:0016208; F:AMP binding; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0019427; P:acetyl-CoA biosynthetic process from acetate; IEA:InterPro.
DR CDD; cd05966; ACS; 1.
DR Gene3D; 3.30.300.30; -; 1.
DR Gene3D; 3.40.50.12780; N-terminal domain of ligase-like; 1.
DR InterPro; IPR011904; Ac_CoA_lig.
DR InterPro; IPR032387; ACAS_N.
DR InterPro; IPR025110; AMP-bd_C.
DR InterPro; IPR045851; AMP-bd_C_sf.
DR InterPro; IPR020845; AMP-binding_CS.
DR InterPro; IPR000873; AMP-dep_Synth/Lig_com.
DR InterPro; IPR042099; ANL_N_sf.
DR NCBIfam; TIGR02188; Ac_CoA_lig_AcsA; 1.
DR PANTHER; PTHR24095; ACETYL-COENZYME A SYNTHETASE; 1.
DR PANTHER; PTHR24095:SF14; ACETYL-COENZYME A SYNTHETASE 1; 1.
DR Pfam; PF16177; ACAS_N; 1.
DR Pfam; PF00501; AMP-binding; 1.
DR Pfam; PF13193; AMP-binding_C; 1.
DR SUPFAM; SSF56801; Acetyl-CoA synthetase-like; 1.
DR PROSITE; PS00455; AMP_BINDING; 1.
PE 4: Predicted;
KW Acetylation {ECO:0000256|ARBA:ARBA00022990};
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Ligase {ECO:0000256|ARBA:ARBA00022598};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741}.
FT DOMAIN 34..87
FT /note="Acetyl-coenzyme A synthetase N-terminal"
FT /evidence="ECO:0000259|Pfam:PF16177"
FT DOMAIN 91..472
FT /note="AMP-dependent synthetase/ligase"
FT /evidence="ECO:0000259|Pfam:PF00501"
FT DOMAIN 532..610
FT /note="AMP-binding enzyme C-terminal"
FT /evidence="ECO:0000259|Pfam:PF13193"
SQ SEQUENCE 633 AA; 72245 MW; 9FF1570823BD801C CRC64;
MSEHKDEVLL KVNKVYQPPK RVLEKAHITA EEFDRMYEES IKDPENFWAN LAEKELHWFK
KWDKVREWEF PNYKWFIGGK LNITYNCLDR HVQNGKRNKV AYIYTNEDNE EIKITYGELL
ELVNRIANGL KSLGVKKGDR VVIYMPLVIE QLATMLACAR IGAIHSVVYA GFSANALRMR
IEDAQAKVIV TSTWTKRRGK KIDLKSVVDE AVDGLDFVEN IVVLQRKGDE FELEEKEIDF
YDLIKDQSSV CEPEIMDAED PLFILYTSGS TGKPKGVLHT TGGYNLYTHV TTKYVFDIHE
DDIFWCTADP GWITGHSYMV YGPLSVGVTS VIAEGAPDYP DPGRWWSIVE KYRVNIFYTA
PTAIRLFMKY GEEWPKKYDL SSLRILGSVG EPINPEAWIW YYEVIGNSQC SIVDTWWQTE
TGGHMITTVP AYPQKPGKAG KPFWGIEADV VDREGYTEEP NKVGYLIIKQ PWPSALRTCW
GEPERFEKYW TEIDHYYFAG DLATKDEDGY IMILGRADDV INVSGHRIGT AEVESALVSH
PAVAEAAVIG KPHDVKGESI KAFVILKQGH EPSENLIKDL KMHVRHELGS LAVPDEIEFV
EKLPKTRSGK IMRRVLKARE LGMPLGDIST LED
//
