ID   A0A285P658_9AQUI        Unreviewed;       369 AA.
AC   A0A285P658;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 14.
DE   SubName: Full=Exonuclease VII, large subunit {ECO:0000313|EMBL:SNZ15636.1};
GN   ORFNames=SAMN06265353_1420 {ECO:0000313|EMBL:SNZ15636.1};
OS   Hydrogenobacter hydrogenophilus.
OC   Bacteria; Aquificota; Aquificae; Aquificales; Aquificaceae;
OC   Hydrogenobacter.
OX   NCBI_TaxID=35835 {ECO:0000313|EMBL:SNZ15636.1, ECO:0000313|Proteomes:UP000218627};
RN   [1] {ECO:0000313|EMBL:SNZ15636.1, ECO:0000313|Proteomes:UP000218627}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2913 {ECO:0000313|EMBL:SNZ15636.1,
RC   ECO:0000313|Proteomes:UP000218627};
RA   Ehlers B., Leendertz F.H.;
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; OBEN01000008; SNZ15636.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A285P658; -.
DR   OrthoDB; 9802795at2; -.
DR   Proteomes; UP000218627; Unassembled WGS sequence.
DR   GO; GO:0009318; C:exodeoxyribonuclease VII complex; IEA:InterPro.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008855; F:exodeoxyribonuclease VII activity; IEA:InterPro.
DR   GO; GO:0006308; P:DNA catabolic process; IEA:InterPro.
DR   InterPro; IPR003753; Exonuc_VII_L.
DR   InterPro; IPR020579; Exonuc_VII_lsu_C.
DR   PANTHER; PTHR30008; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR   PANTHER; PTHR30008:SF0; EXODEOXYRIBONUCLEASE 7 LARGE SUBUNIT; 1.
DR   Pfam; PF02601; Exonuc_VII_L; 1.
PE   4: Predicted;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Exonuclease {ECO:0000313|EMBL:SNZ15636.1};
KW   Hydrolase {ECO:0000313|EMBL:SNZ15636.1};
KW   Membrane {ECO:0000256|SAM:Phobius}; Nuclease {ECO:0000313|EMBL:SNZ15636.1};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        348..368
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          122..339
FT                   /note="Exonuclease VII large subunit C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF02601"
FT   COILED          276..341
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   369 AA;  42704 MW;  74E75452D9032F3F CRC64;
     MSYLTPKEIF DSLQSKLERD VIKAVGILKQ ERGYLKLSDG EHAIDLNFPE EFDLPLGAKI
     EVEGFLTYYL HRLGGGIYPR LNVKAFKVLE DGQETSQRLE LLERLRQSRK ERILIHELPK
     IANPLRIVVI HGRSAQTQQD FYRGFFQSIG EFRNRVEFSF IETSLSDEEL AQTIQELKDQ
     EFDAIFLVRG GGSQEELSKV GGLLSALAIL ELSKPFYIAI GHSLDRNLSL LELIADQSFD
     TPSLAGTSLG KAVRDHALIE RLIEELGHTK EKLIYLEKLK EENNTLKEQL MEKEREREKI
     KMELEHLKGE LKYLEKFKEA NNTLREKLWE EEKEKEKIKM ELKSARNYFM LSLVLNAILL
     VLVLILLFK
//