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Database: UniProt
Entry: A0A285PGF7_9RHIZ
LinkDB: A0A285PGF7_9RHIZ
Original site: A0A285PGF7_9RHIZ 
ID   A0A285PGF7_9RHIZ        Unreviewed;       666 AA.
AC   A0A285PGF7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   11-DEC-2019, entry version 7.
DE   RecName: Full=DNA primase {ECO:0000256|HAMAP-Rule:MF_00974, ECO:0000256|PIRNR:PIRNR002811, ECO:0000256|SAAS:SAAS00993443};
DE            EC=2.7.7.- {ECO:0000256|HAMAP-Rule:MF_00974, ECO:0000256|PIRNR:PIRNR002811, ECO:0000256|SAAS:SAAS00993444};
GN   Name=dnaG {ECO:0000256|HAMAP-Rule:MF_00974};
GN   ORFNames=SAMN06265368_3926 {ECO:0000313|EMBL:SNZ20815.1};
OS   Cohaesibacter gelatinilyticus.
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Cohaesibacteraceae.
OX   NCBI_TaxID=372072 {ECO:0000313|EMBL:SNZ20815.1, ECO:0000313|Proteomes:UP000219439};
RN   [1] {ECO:0000313|EMBL:SNZ20815.1, ECO:0000313|Proteomes:UP000219439}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 18289 {ECO:0000313|EMBL:SNZ20815.1,
RC   ECO:0000313|Proteomes:UP000219439};
RA   Ehlers B., Leendertz F.H.;
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: RNA polymerase that catalyzes the synthesis of short RNA
CC       molecules used as primers for DNA polymerase during DNA replication.
CC       {ECO:0000256|HAMAP-Rule:MF_00974, ECO:0000256|PIRNR:PIRNR002811,
CC       ECO:0000256|SAAS:SAAS00709340}.
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000256|SAAS:SAAS00709317};
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000256|PIRNR:PIRNR002811};
CC       Note=Binds 1 zinc ion per monomer. {ECO:0000256|PIRNR:PIRNR002811};
CC   -!- SUBUNIT: Monomer. Interacts with DnaB. {ECO:0000256|HAMAP-
CC       Rule:MF_00974}.
CC   -!- SIMILARITY: Belongs to the DnaG primase family. {ECO:0000256|HAMAP-
CC       Rule:MF_00974, ECO:0000256|PIRNR:PIRNR002811,
CC       ECO:0000256|SAAS:SAAS00709351}.
CC   -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC       feature annotation. {ECO:0000256|HAMAP-Rule:MF_00974}.
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DR   EMBL; OBEL01000006; SNZ20815.1; -; Genomic_DNA.
DR   Proteomes; UP000219439; Unassembled WGS sequence.
DR   GO; GO:1990077; C:primosome complex; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0003896; F:DNA primase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR   CDD; cd03364; TOPRIM_DnaG_primases; 1.
DR   Gene3D; 3.90.580.10; -; 1.
DR   Gene3D; 3.90.980.10; -; 1.
DR   HAMAP; MF_00974; DNA_primase_DnaG; 1.
DR   InterPro; IPR013264; DNA_primase_core_N.
DR   InterPro; IPR037068; DNA_primase_core_N_sf.
DR   InterPro; IPR006295; DNA_primase_DnaG.
DR   InterPro; IPR036977; DNA_primase_Znf_CHC2.
DR   InterPro; IPR030846; DnaG_bac.
DR   InterPro; IPR034151; TOPRIM_DnaG_bac.
DR   InterPro; IPR006171; TOPRIM_domain.
DR   InterPro; IPR002694; Znf_CHC2.
DR   Pfam; PF13662; Toprim_4; 1.
DR   Pfam; PF08275; Toprim_N; 1.
DR   Pfam; PF01807; zf-CHC2; 1.
DR   PIRSF; PIRSF002811; DnaG; 2.
DR   SMART; SM00493; TOPRIM; 1.
DR   SMART; SM00400; ZnF_CHCC; 1.
DR   TIGRFAMs; TIGR01391; dnaG; 1.
DR   PROSITE; PS50880; TOPRIM; 1.
PE   3: Inferred from homology;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   DNA replication {ECO:0000256|HAMAP-Rule:MF_00974,
KW   ECO:0000256|PIRNR:PIRNR002811, ECO:0000256|SAAS:SAAS00993445};
KW   DNA-binding {ECO:0000256|HAMAP-Rule:MF_00974,
KW   ECO:0000256|SAAS:SAAS00709369};
KW   DNA-directed RNA polymerase {ECO:0000256|HAMAP-Rule:MF_00974,
KW   ECO:0000256|PIRNR:PIRNR002811, ECO:0000256|SAAS:SAAS00709327};
KW   Magnesium {ECO:0000256|SAAS:SAAS00709345};
KW   Metal-binding {ECO:0000256|PIRNR:PIRNR002811,
KW   ECO:0000256|SAAS:SAAS00709338};
KW   Nucleotidyltransferase {ECO:0000256|HAMAP-Rule:MF_00974,
KW   ECO:0000256|PIRNR:PIRNR002811, ECO:0000256|SAAS:SAAS00709339};
KW   Primosome {ECO:0000256|HAMAP-Rule:MF_00974, ECO:0000256|PIRNR:PIRNR002811,
KW   ECO:0000256|SAAS:SAAS00709304};
KW   Reference proteome {ECO:0000313|Proteomes:UP000219439};
KW   Transcription {ECO:0000256|HAMAP-Rule:MF_00974,
KW   ECO:0000256|PIRNR:PIRNR002811, ECO:0000256|SAAS:SAAS00709341};
KW   Transferase {ECO:0000256|HAMAP-Rule:MF_00974,
KW   ECO:0000256|PIRNR:PIRNR002811, ECO:0000256|SAAS:SAAS00993442};
KW   Zinc {ECO:0000256|PIRNR:PIRNR002811, ECO:0000256|SAAS:SAAS00709300};
KW   Zinc-finger {ECO:0000256|SAAS:SAAS00709301}.
FT   DOMAIN          257..339
FT                   /note="Toprim"
FT                   /evidence="ECO:0000259|PROSITE:PS50880"
FT   COILED          386..406
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          616..636
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   666 AA;  74643 MW;  8D9807D48A55269E CRC64;
     MKIPPSLLDD IRDRISVSDV VGRKVKLRRH GREYMGLSPF NKEKTPSFTV NDQKQFYHCF
     SSGKHGDVFK FLMETEGLSF PEAVERLAGE AGIALPSPDP QAQRREQEKA SLYDVMEMAT
     KYFQLQFSSD LGLEARRYAN GRGLTAETLS TFRFGFAVNS RDHLKSYLLQ RGVSEADMLA
     TGLVIKPDDG RPTYDRFRNR LMIPIEDERG RVVAFGGRIL DPDGKPKYLN SPETKLFHKG
     YMLFNAKRAR QAAYEAKAAI VTEGYMDVIA LHQAGIPYAV ASLGTAFTEH QIAQLWKLAP
     EPYICFDGDR AGRAAANRAI ERILPQLKAG FSFQFAFMPE GQDPDDVVKQ GGSNAFHELL
     AKALPLSDVV WQRELNAGPT DTPERKAALE KRIEDLLRSI QDERVARQYQ MSFKSALSNH
     FWLQSRQQRE QKFTGGGARA GRGAGANAAL AASSNVSRVP EAGQFTEFEE NILGLCVHMP
     SLFEDYAEQI LSLSFHKPGL EPFKQVLAHL ILDEEVEHYS DIYAKAPGEL EPLLQDLHGK
     GSQDEDGKRT SPFGWRLASR SKVPQLAYSP GRIFLERLMS YWLSVLEVRD VQADLEQETA
     LALSDCDASD AAFERIQALT QEVHRRREEN AREDQELTDE YAKMKSAGVQ ATLSDCLAEL
     AEKSAD
//
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