ID   A0A285QNS4_9ACTN        Unreviewed;       423 AA.
AC   A0A285QNS4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 16.
DE   SubName: Full=Regulator of protease activity HflC, stomatin/prohibitin superfamily {ECO:0000313|EMBL:SOB83059.1};
GN   ORFNames=SAMN06272789_3256 {ECO:0000313|EMBL:SOB83059.1};
OS   Streptomyces sp. 1331.2.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1938835 {ECO:0000313|EMBL:SOB83059.1, ECO:0000313|Proteomes:UP000219030};
RN   [1] {ECO:0000313|Proteomes:UP000219030}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1331.2 {ECO:0000313|Proteomes:UP000219030};
RA   Varghese N., Submissions S.;
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
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DR   EMBL; OBMJ01000001; SOB83059.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A285QNS4; -.
DR   Proteomes; UP000219030; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0008233; F:peptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.479.30; Band 7 domain; 1.
DR   InterPro; IPR001107; Band_7.
DR   InterPro; IPR036013; Band_7/SPFH_dom_sf.
DR   PANTHER; PTHR43446; MEMBRANE PROTEIN-RELATED; 1.
DR   PANTHER; PTHR43446:SF1; MEMBRANE PROTEIN-RELATED; 1.
DR   Pfam; PF01145; Band_7; 1.
DR   SMART; SM00244; PHB; 1.
DR   SUPFAM; SSF117892; Band 7/SPFH domain; 1.
PE   4: Predicted;
KW   Hydrolase {ECO:0000313|EMBL:SOB83059.1};
KW   Membrane {ECO:0000256|SAM:Phobius}; Protease {ECO:0000313|EMBL:SOB83059.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000219030};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        116..137
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        168..190
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          184..347
FT                   /note="Band 7"
FT                   /evidence="ECO:0000259|SMART:SM00244"
FT   REGION          1..29
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          44..64
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          86..105
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   423 AA;  44745 MW;  A94B3D4E6605B9F7 CRC64;
     MDVTRDSSQR PENLSKAFPP AVPERFASDA GPLAGASAIR AVKAAPADSG PATTSLAVLP
     GPSSVGPVDL RDPLEAAAPE TVELLDPVRT GASTAATSRR PPRADQALRE HAATTLPGWL
     ALLVLLLGLA GALFVLLRTG VVPHWEVLPD LRGAGARASG RAEVDARAIA GVSASGLLVV
     LALAGLLANA GGETRVLSRW GRYRGTVRRT GLVWVNPLLR RRRVDVRLRH WRSEPVKVVD
     RTGTPIVVRL LVVWRVKDTA RALLAIEDHE GYLREQVQAV LTRTASTLPC DSNAAPGPAL
     RDGQWFADEM TRALAAEAAP AGLEVYSVQP LALDYAPEVA ESMRRRRLAD LDAGLRTVLV
     DDAVEAAALA VRRLERATAH ELDEAARSAL MEQLLVAFVA PAGLAASVPP PAARAGRKEG
     RPA
//