ID   A0A285QW03_9ACTN        Unreviewed;       995 AA.
AC   A0A285QW03;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 20.
DE   SubName: Full=DNA-binding transcriptional activator of the SARP family {ECO:0000313|EMBL:SOB85569.1};
GN   ORFNames=SAMN06272789_5858 {ECO:0000313|EMBL:SOB85569.1};
OS   Streptomyces sp. 1331.2.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1938835 {ECO:0000313|EMBL:SOB85569.1, ECO:0000313|Proteomes:UP000219030};
RN   [1] {ECO:0000313|Proteomes:UP000219030}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1331.2 {ECO:0000313|Proteomes:UP000219030};
RA   Varghese N., Submissions S.;
RL   Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SIMILARITY: Belongs to the AfsR/DnrI/RedD regulatory family.
CC       {ECO:0000256|ARBA:ARBA00005820}.
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DR   EMBL; OBMJ01000001; SOB85569.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A285QW03; -.
DR   Proteomes; UP000219030; Unassembled WGS sequence.
DR   GO; GO:0043531; F:ADP binding; IEA:InterPro.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0000160; P:phosphorelay signal transduction system; IEA:UniProtKB-KW.
DR   GO; GO:0006355; P:regulation of DNA-templated transcription; IEA:InterPro.
DR   CDD; cd15831; BTAD; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR   Gene3D; 1.25.40.10; Tetratricopeptide repeat domain; 3.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR005158; BTAD.
DR   InterPro; IPR002182; NB-ARC.
DR   InterPro; IPR001867; OmpR/PhoB-type_DNA-bd.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR016032; Sig_transdc_resp-reg_C-effctor.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   PANTHER; PTHR35807:SF1; TRANSCRIPTIONAL REGULATOR REDD; 1.
DR   PANTHER; PTHR35807; TRANSCRIPTIONAL REGULATOR REDD-RELATED; 1.
DR   Pfam; PF03704; BTAD; 1.
DR   Pfam; PF00931; NB-ARC; 1.
DR   Pfam; PF13181; TPR_8; 1.
DR   Pfam; PF00486; Trans_reg_C; 1.
DR   PRINTS; PR00364; DISEASERSIST.
DR   SMART; SM01043; BTAD; 1.
DR   SMART; SM00028; TPR; 5.
DR   SMART; SM00862; Trans_reg_C; 1.
DR   SUPFAM; SSF46894; C-terminal effector domain of the bipartite response regulators; 1.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR   SUPFAM; SSF48452; TPR-like; 2.
DR   PROSITE; PS51755; OMPR_PHOB; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|PROSITE-
KW   ProRule:PRU01091}; Reference proteome {ECO:0000313|Proteomes:UP000219030};
KW   Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT   DOMAIN          1..98
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000259|PROSITE:PS51755"
FT   DNA_BIND        1..98
FT                   /note="OmpR/PhoB-type"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01091"
SQ   SEQUENCE   995 AA;  106371 MW;  A02EA3ED5DF8A6D4 CRC64;
     MIQPIRFRLL GPMAAHRDEE GLVVGSPLQQ AMMAALLLRD GRAASAGELI EAVWGPTAPA
     SASAMLRTYA WRWRKALERD RSAPVVLTSV GDGYRTVLPA ENVDAVRVES LAAAALAATR
     KAEDHPRARQ LLDEALDLWY GEPLAGIPGP LAEQHRARLE DLRISLLEEK CGLDLELGVP
     GRAVPVLREL NADHPLRERP YVLLMRGLYQ SGRQADALAV FERVRRLLAA ELGIDPGPEL
     RAMHQRILRN DPSLLPAAPP EPEPSVTART ATGTAPAVPV PAQLPADIAD FTGREDELAA
     LHTALGKAVQ DTAGHTVLPI AAISGMGGVG KTTVALRVAH RLRAGFPDGQ LYADLRGDQP
     KPAQPGVLLV SFLTALGVAP GAVPETLEDR SRLFRSLLDG RRVLILLDNA RDAAQVRPLL
     PGSARCAVLV TSRTRLFGLA TAVQVDLDVF SVDEATGMLA QAAGDDRIDA DPAAAGELIR
     YCGRLPLAIR IVASRLASRP SWSVARLADR LAAEQHRMSE LQIGDLAVAS AFEWGYRQLT
     PEQATAFRVV AAVSRPDIGV PVAAVVLGVE QRRAEDLLEA LVDAGMVSET HAGRYRYHEL
     LRVFASQLTE PDDAVDSATA LSRQLDFLLA TATAAFQQVV PGDPIGSALR TPALAGLRFD
     TPRAAARWVG EEFDTAIAAM QAATAPDGSA QDLRTAADLL IALCPFDADP RYERLAVAAA
     AVSAAATGRA DRHSLGRAEF IRGNLAVQAT RLGEATEHCR RAAEACREVG DRVILQQVLN
     DLGLLAQFQH RFEEAVRLCE EAHELAVALG HHTGRTVTLL NAAMARVRGG APAEGARVCR
     ELLPALRAEE DLPGVSYALF VLGLAAHQCE SYQEAAATFR ECLELCRSAG LALREAQARY
     RLADTLRRLG RGAEAVTGAR QAVAECEALT ADRDRAHALV VLARALADRG RIAEAREHLT
     EAEALFDRLE LPDGELVRAL LADLDAAGAA ESAAG
//