ID A0A285R0N9_9SPHN Unreviewed; 595 AA.
AC A0A285R0N9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 16.
DE RecName: Full=Endoglucanase {ECO:0000256|RuleBase:RU361166};
DE EC=3.2.1.4 {ECO:0000256|RuleBase:RU361166};
GN ORFNames=SAMN06297144_2536 {ECO:0000313|EMBL:SOB87404.1};
OS Sphingomonas guangdongensis.
OC Bacteria; Pseudomonadota; Alphaproteobacteria; Sphingomonadales;
OC Sphingomonadaceae; Sphingomonas.
OX NCBI_TaxID=1141890 {ECO:0000313|EMBL:SOB87404.1, ECO:0000313|Proteomes:UP000219494};
RN [1] {ECO:0000313|EMBL:SOB87404.1, ECO:0000313|Proteomes:UP000219494}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.12672 {ECO:0000313|EMBL:SOB87404.1,
RC ECO:0000313|Proteomes:UP000219494};
RA Sun Z.S., Albrecht U., Echele G., Lee C.C.;
RL Submitted (JUL-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- CATALYTIC ACTIVITY:
CC Reaction=Endohydrolysis of (1->4)-beta-D-glucosidic linkages in
CC cellulose, lichenin and cereal beta-D-glucans.; EC=3.2.1.4;
CC Evidence={ECO:0000256|RuleBase:RU361166};
CC -!- SIMILARITY: Belongs to the glycosyl hydrolase 9 (cellulase E) family.
CC {ECO:0000256|PROSITE-ProRule:PRU10060, ECO:0000256|RuleBase:RU361166}.
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DR EMBL; OBMI01000003; SOB87404.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A285R0N9; -.
DR OrthoDB; 9808897at2; -.
DR Proteomes; UP000219494; Unassembled WGS sequence.
DR GO; GO:0008810; F:cellulase activity; IEA:UniProtKB-EC.
DR GO; GO:0030245; P:cellulose catabolic process; IEA:UniProtKB-KW.
DR CDD; cd02850; E_set_Cellulase_N; 1.
DR Gene3D; 1.50.10.10; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 1.
DR InterPro; IPR008928; 6-hairpin_glycosidase_sf.
DR InterPro; IPR012341; 6hp_glycosidase-like_sf.
DR InterPro; IPR004197; Cellulase_Ig-like.
DR InterPro; IPR001701; Glyco_hydro_9.
DR InterPro; IPR033126; Glyco_hydro_9_Asp/Glu_AS.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR014756; Ig_E-set.
DR PANTHER; PTHR22298; ENDO-1,4-BETA-GLUCANASE; 1.
DR PANTHER; PTHR22298:SF29; ENDOGLUCANASE; 1.
DR Pfam; PF02927; CelD_N; 1.
DR Pfam; PF00759; Glyco_hydro_9; 1.
DR SUPFAM; SSF81296; E set domains; 1.
DR SUPFAM; SSF48208; Six-hairpin glycosidases; 1.
DR PROSITE; PS00698; GH9_3; 1.
PE 3: Inferred from homology;
KW Carbohydrate metabolism {ECO:0000256|ARBA:ARBA00023277,
KW ECO:0000256|PROSITE-ProRule:PRU10060};
KW Cellulose degradation {ECO:0000256|RuleBase:RU361166};
KW Glycosidase {ECO:0000256|ARBA:ARBA00023295, ECO:0000256|PROSITE-
KW ProRule:PRU10060};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801, ECO:0000256|PROSITE-
KW ProRule:PRU10060};
KW Polysaccharide degradation {ECO:0000256|ARBA:ARBA00023326,
KW ECO:0000256|PROSITE-ProRule:PRU10060};
KW Reference proteome {ECO:0000313|Proteomes:UP000219494};
KW Signal {ECO:0000256|RuleBase:RU361166}.
FT SIGNAL 1..17
FT /evidence="ECO:0000256|RuleBase:RU361166"
FT CHAIN 18..595
FT /note="Endoglucanase"
FT /evidence="ECO:0000256|RuleBase:RU361166"
FT /id="PRO_5011826501"
FT DOMAIN 20..100
FT /note="Cellulase Ig-like"
FT /evidence="ECO:0000259|Pfam:PF02927"
FT DOMAIN 111..584
FT /note="Glycoside hydrolase family 9"
FT /evidence="ECO:0000259|Pfam:PF00759"
FT ACT_SITE 563
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10060"
FT ACT_SITE 572
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU10060"
SQ SEQUENCE 595 AA; 64461 MW; 46BC0A9759ED3C56 CRC64;
MRLLAAAALA IAAPAAAQVG AVRLNGVGFA PGAPKRAIVE TTATRPLAWQ VTGADGRVLL
RGRTVPYGRD AASGRSLHRA DFSALRRPGN GLVVKVGDST SPRFAIAAHP YAALARDALA
YFYHNRAGTA IEARLVGERW ARPAAHTREY ATCVSGKDTR SNDWPNCGYA MDVTGGWYDA
GDHGKYVVNG GIATWTLLNL YERLPTRFGD NSLRVPEANN GTSDLLDEAR NEVEFLLKMQ
VPEGRRMRLP VDQPDASKPL RFSEVEIGGM AHHKVADRNW TALPMRPDRD REERVLHPPS
TAATLNLAAV AAQCARIWRT IDAGFARRCA EAADRAWAAA ERNGAIYFVS DFTGSGNYGD
SDLTDERFWA AAELYATTRD ARYLAVLQGS SFLQQSAREP GWPSVSALGL VSLALTDTPL
RAEARQRIIA AADGWTRERD RTGFAIPYAG TRFAWGSNSN LLNRAMLIAL AYDWTREPRY
RAAVVDVMDY LLGRNPVGRS YVSGYGTDPM RAPHHRFWAA GIDPAYPPPP PGVVSGGPNN
GGSRTDGVEG MAADCAPMAC WSDNARAFAL NEVAINWNAP LAWVAAWLDA TEPAA
//
