ID A0A286CX94_9GAMM Unreviewed; 775 AA.
AC A0A286CX94;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 24-JAN-2024, entry version 13.
DE SubName: Full=Competence protein ComEC {ECO:0000313|EMBL:SOD51036.1};
GN ORFNames=SAMN06296416_101417 {ECO:0000313|EMBL:SOD51036.1};
OS Pseudoxanthomonas wuyuanensis.
OC Bacteria; Pseudomonadota; Gammaproteobacteria; Xanthomonadales;
OC Xanthomonadaceae; Pseudoxanthomonas.
OX NCBI_TaxID=1073196 {ECO:0000313|EMBL:SOD51036.1, ECO:0000313|Proteomes:UP000219374};
RN [1] {ECO:0000313|EMBL:SOD51036.1, ECO:0000313|Proteomes:UP000219374}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 1.10978 {ECO:0000313|EMBL:SOD51036.1,
RC ECO:0000313|Proteomes:UP000219374};
RA Ehlers B., Leendertz F.H.;
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR EMBL; OCND01000001; SOD51036.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A286CX94; -.
DR OrthoDB; 9761531at2; -.
DR Proteomes; UP000219374; Unassembled WGS sequence.
DR GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:InterPro.
DR CDD; cd07731; ComA-like_MBL-fold; 1.
DR Gene3D; 3.60.15.10; Ribonuclease Z/Hydroxyacylglutathione hydrolase-like; 1.
DR InterPro; IPR035681; ComA-like_MBL.
DR InterPro; IPR004477; ComEC_N.
DR InterPro; IPR004797; Competence_ComEC/Rec2.
DR InterPro; IPR025405; DUF4131.
DR InterPro; IPR001279; Metallo-B-lactamas.
DR InterPro; IPR036866; RibonucZ/Hydroxyglut_hydro.
DR NCBIfam; TIGR00360; ComEC_N-term; 1.
DR NCBIfam; TIGR00361; ComEC_Rec2; 1.
DR PANTHER; PTHR30619; DNA INTERNALIZATION/COMPETENCE PROTEIN COMEC/REC2; 1.
DR PANTHER; PTHR30619:SF1; RECOMBINATION PROTEIN 2; 1.
DR Pfam; PF03772; Competence; 1.
DR Pfam; PF13567; DUF4131; 1.
DR Pfam; PF00753; Lactamase_B; 1.
DR SMART; SM00849; Lactamase_B; 1.
DR SUPFAM; SSF56281; Metallo-hydrolase/oxidoreductase; 1.
DR PROSITE; PS51257; PROKAR_LIPOPROTEIN; 1.
PE 4: Predicted;
KW Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000219374};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 37..54
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 254..277
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 297..327
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 339..372
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 384..403
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 415..433
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 445..465
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 477..494
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 533..718
FT /note="Metallo-beta-lactamase"
FT /evidence="ECO:0000259|SMART:SM00849"
SQ SEQUENCE 775 AA; 83920 MW; 25599E99EA49402E CRC64;
MGNAVVRSAP SRLGIATAAA TLAGVGACLC LPALAPWPVI VVCLLLGVGI WARGRRAYLL
GPVLFGFGWA SLHASWGLSA QLPVAMEQAE LSVEGRIVGL PEMEVRRTRF RFRVDDSPTQ
PQALRGRLLQ LSWYDDFGAT EPGPRKHLQA GARWRMTVKL RAPRGLINPG GFDSERHALA
QRISATGYLR QPQTARRLAG PVGIDAWREA MSARIQASAP ASSSRYVRAL ALGDTRALDD
RDWEILRASG LTHLIAISGF HVGLVSGFFA LLGAGIWRLF PHWSRRMPRP QVAGLAALLG
ACGYAAVAGF ALPTVRTVLM IAVVVAARLW RRPVRVADAL ALAMTAVLLF DPLSVLVAGF
WLSFAGVAWL VWCLPQQTSV WKGFLSAQGV ATLGLLPLTV ILFDQASLAG PFANLLAIPW
WSLVVVPLSL IGTALEALRP GWGDWAWQAA AWCFDLAWPV FVWLAESRFA LWWLPESRWF
ALPLAMLGAF WLLLPRGVPG KALAALLWLP LLWPDRELPA QGEAELVMVD VGQGLAVLVR
TASHALLYDA GPAVRDGFDA GERAVVPALR ALGVPRLDRV VVSHGDQDHA GGVEAVLSVV
PAGEVLAPAG SPTPADAACQ SGQSWQWDGV RFRFLHPTAH FPYLRNEASC VLRVETRHGT
VLLTGDIGEV VERELVRRDP AAVRAQVVLA PHHGSAGSSD PAFVAASGAR LVLFSSGYGN
RFGHPRSEVI ERWRDAGAEV LVTESSGAVR VWLGADGLQL RERRHDRRRL WRATR
//
