ID   A0A286DIK9_9ACTN        Unreviewed;       760 AA.
AC   A0A286DIK9;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   SubName: Full=Oxidoreductase alpha (Molybdopterin) subunit {ECO:0000313|EMBL:SOD58488.1};
GN   ORFNames=SAMN06297387_101172 {ECO:0000313|EMBL:SOD58488.1};
OS   Streptomyces zhaozhouensis.
OC   Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC   Streptomycetaceae; Streptomyces.
OX   NCBI_TaxID=1300267 {ECO:0000313|EMBL:SOD58488.1, ECO:0000313|Proteomes:UP000219072};
RN   [1] {ECO:0000313|EMBL:SOD58488.1, ECO:0000313|Proteomes:UP000219072}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CGMCC 4.7095 {ECO:0000313|EMBL:SOD58488.1,
RC   ECO:0000313|Proteomes:UP000219072};
RA   Ehlers B., Leendertz F.H.;
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- COFACTOR:
CC       Name=Mo-bis(molybdopterin guanine dinucleotide);
CC         Xref=ChEBI:CHEBI:60539; Evidence={ECO:0000256|ARBA:ARBA00001942};
CC   -!- COFACTOR:
CC       Name=[4Fe-4S] cluster; Xref=ChEBI:CHEBI:49883;
CC         Evidence={ECO:0000256|ARBA:ARBA00001966};
CC   -!- SIMILARITY: Belongs to the prokaryotic molybdopterin-containing
CC       oxidoreductase family. {ECO:0000256|ARBA:ARBA00010312}.
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DR   EMBL; OCNE01000001; SOD58488.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A286DIK9; -.
DR   OrthoDB; 5287431at2; -.
DR   Proteomes; UP000219072; Unassembled WGS sequence.
DR   GO; GO:0051539; F:4 iron, 4 sulfur cluster binding; IEA:InterPro.
DR   GO; GO:0008863; F:formate dehydrogenase (NAD+) activity; IEA:InterPro.
DR   GO; GO:0030151; F:molybdenum ion binding; IEA:InterPro.
DR   GO; GO:0043546; F:molybdopterin cofactor binding; IEA:InterPro.
DR   CDD; cd02787; MopB_CT_ydeP; 1.
DR   CDD; cd02767; MopB_ydeP; 1.
DR   Gene3D; 2.40.40.20; -; 1.
DR   Gene3D; 3.40.50.740; -; 1.
DR   Gene3D; 3.40.228.10; Dimethylsulfoxide Reductase, domain 2; 1.
DR   InterPro; IPR009010; Asp_de-COase-like_dom_sf.
DR   InterPro; IPR037951; MopB_CT_YdeP.
DR   InterPro; IPR006657; MoPterin_dinucl-bd_dom.
DR   InterPro; IPR006656; Mopterin_OxRdtase.
DR   InterPro; IPR010046; Mopterin_OxRdtse_a_bac.
DR   InterPro; IPR041953; YdeP_MopB.
DR   NCBIfam; TIGR01701; Fdhalpha-like; 1.
DR   PANTHER; PTHR43105:SF4; PROTEIN YDEP; 1.
DR   PANTHER; PTHR43105; RESPIRATORY NITRATE REDUCTASE; 1.
DR   Pfam; PF00384; Molybdopterin; 1.
DR   Pfam; PF01568; Molydop_binding; 1.
DR   PIRSF; PIRSF000144; CbbBc; 1.
DR   SUPFAM; SSF50692; ADC-like; 1.
DR   SUPFAM; SSF53706; Formate dehydrogenase/DMSO reductase, domains 1-3; 1.
PE   3: Inferred from homology;
KW   4Fe-4S {ECO:0000256|ARBA:ARBA00022485};
KW   Iron {ECO:0000256|ARBA:ARBA00023004};
KW   Iron-sulfur {ECO:0000256|ARBA:ARBA00023014};
KW   Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW   Oxidoreductase {ECO:0000256|ARBA:ARBA00023002};
KW   Reference proteome {ECO:0000313|Proteomes:UP000219072}.
FT   DOMAIN          120..491
FT                   /note="Molybdopterin oxidoreductase"
FT                   /evidence="ECO:0000259|Pfam:PF00384"
FT   DOMAIN          642..749
FT                   /note="Molybdopterin dinucleotide-binding"
FT                   /evidence="ECO:0000259|Pfam:PF01568"
FT   REGION          1..23
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   760 AA;  82551 MW;  F60F0CFB88400D54 CRC64;
     MAARPPADDP VQDAPDVGAP QHAAAGLPAV GHSLRMAQRQ MGARRTALTL LRVNQRDGFD
     CPGCAWPEPD KPHRAEFCEN GAKAVAEEAT LRRVTPAFFA EHALEELSGR SGYWLGQQGR
     LTEPMYLAEG ATHYRPIGWD EAFDLVAEEL TALDSPDEAV FYTSGRTSNE AAFLYQLLAR
     EFGTNNLPDC SNLCHESSGS ALTETLGVGK GSVLLEDLYR ADLIVVAGQN PGTNHPRMLS
     ALERAKARGA RIITVNPLPE AGLERFRNPQ TPRGLVGGGT ALTDLFLQVR LGGDQALFRM
     LNRLIVERDA VDRAFVEAHT HGYAELAEAA LATGWEETLA ATGLAREEIE RALEMTLAAD
     SVVVCWAMGL TQHQHAVATI KEVVNYLLLR GNIGRPGAGV CPVRGHSNVQ GDRTMGIVER
     PGEAFLDALR DEFGFEPPRH HGHDVVNAIR ALRDGRAKVF FAMGGNFVAA SPDTEVTERA
     MRRARLTVHV STKLNRSHCV TGARALILPT LGRTERDVQA GGEQFVTVED SMGQVHASRG
     RLRPASERLL SEPAIVCRLA RRVLGPDSAT PWEEFEADYA AVRARIARVV PGFEDFETRV
     GRPGGFTLPH APRDERRFPT ATGLAHFSAG PVTYPRVPEG RLLLQTLRSH DQYNTTVYGL
     DDRYRGITGG RRVVLVNPGD AAERGLSDGD FVDLTSEWTD GTERVAPGFR LVVYPTAPGC
     AAAYYPETNV LVPLDATAET SNTPVSKSVV IRLTPGTRCQ
//