ID A0A286E2Z0_9ACTN Unreviewed; 460 AA.
AC A0A286E2Z0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 16.
DE SubName: Full=Histidine kinase {ECO:0000313|EMBL:SOD65288.1};
GN ORFNames=SAMN06297387_12182 {ECO:0000313|EMBL:SOD65288.1};
OS Streptomyces zhaozhouensis.
OC Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales;
OC Streptomycetaceae; Streptomyces.
OX NCBI_TaxID=1300267 {ECO:0000313|EMBL:SOD65288.1, ECO:0000313|Proteomes:UP000219072};
RN [1] {ECO:0000313|EMBL:SOD65288.1, ECO:0000313|Proteomes:UP000219072}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CGMCC 4.7095 {ECO:0000313|EMBL:SOD65288.1,
RC ECO:0000313|Proteomes:UP000219072};
RA Ehlers B., Leendertz F.H.;
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
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DR EMBL; OCNE01000021; SOD65288.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A286E2Z0; -.
DR OrthoDB; 227596at2; -.
DR Proteomes; UP000219072; Unassembled WGS sequence.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0000155; F:phosphorelay sensor kinase activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd16917; HATPase_UhpB-NarQ-NarX-like; 1.
DR Gene3D; 1.20.5.1930; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR011712; Sig_transdc_His_kin_sub3_dim/P.
DR PANTHER; PTHR24421; NITRATE/NITRITE SENSOR PROTEIN NARX-RELATED; 1.
DR PANTHER; PTHR24421:SF10; SENSORY TRANSDUCTION HISTIDINE KINASE; 1.
DR Pfam; PF07730; HisKA_3; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
PE 4: Predicted;
KW Kinase {ECO:0000256|ARBA:ARBA00022777, ECO:0000313|EMBL:SOD65288.1};
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000219072};
KW Transferase {ECO:0000256|ARBA:ARBA00022679};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius};
KW Two-component regulatory system {ECO:0000256|ARBA:ARBA00023012}.
FT TRANSMEM 50..69
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 75..98
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 110..130
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT TRANSMEM 150..168
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT DOMAIN 207..272
FT /note="Signal transduction histidine kinase subgroup 3
FT dimerisation and phosphoacceptor"
FT /evidence="ECO:0000259|Pfam:PF07730"
FT REGION 270..326
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 460 AA; 48915 MW; 29D6435031995BDA CRC64;
MDAKGAPTAG EDFRLLWWTR RRSVALDAGL ALLSAVECGS QGVGFAEQTG LPVALVVVPG
VLAGLSLLVR RRWPLAVILI SIAVLPANMG VMLALLGLYT LATTDAPRRV IAALASMEGL
GTIIVTYLML DTDPGIREQD FPAWFRPLVA LLFGVASVVP PVLLGMYVRA RRRLVETLRD
RALGLERELG LLAERAEERA EWARDEERRR IAREMHDVVA HRVSLMVVHA AAVQAVAPKD
PEKAARNASL IGDMGRQALT ELRTMLGVLR SAPVAPDRPT ESSRASSRLA EIASGQGREP
SAEGEPAPDG EAPAAPGPNG DGPRLTGLRA LVEESRAAGM RVELAVEGEQ RGYPEQVEST
AYRVVQEALT NVHKHAAGAA AWVRLAHREG EIAVQVRNAA PDGAARRREE AILPSGGNGL
VGMRERVTAL GGGFVSGPTD EGGFRVSAVI PDRSEGRPGG
//
