ID   A0A286G8Z4_9PROT        Unreviewed;       811 AA.
AC   A0A286G8Z4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 22.
DE   RecName: Full=endopeptidase La {ECO:0000256|PROSITE-ProRule:PRU01122};
DE            EC=3.4.21.53 {ECO:0000256|PROSITE-ProRule:PRU01122};
GN   ORFNames=SAMN05421508_102197 {ECO:0000313|EMBL:SOD91965.1};
OS   Caenispirillum bisanense.
OC   Bacteria; Pseudomonadota; Alphaproteobacteria; Rhodospirillales;
OC   Novispirillaceae; Caenispirillum.
OX   NCBI_TaxID=414052 {ECO:0000313|EMBL:SOD91965.1, ECO:0000313|Proteomes:UP000219621};
RN   [1] {ECO:0000313|EMBL:SOD91965.1, ECO:0000313|Proteomes:UP000219621}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=USBA 140 {ECO:0000313|EMBL:SOD91965.1,
RC   ECO:0000313|Proteomes:UP000219621};
RA   Ehlers B., Leendertz F.H.;
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Hydrolysis of proteins in presence of ATP.; EC=3.4.21.53;
CC         Evidence={ECO:0000256|PROSITE-ProRule:PRU01122};
CC   -!- SIMILARITY: Belongs to the peptidase S16 family. {ECO:0000256|PROSITE-
CC       ProRule:PRU01122}.
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DR   EMBL; OCNJ01000002; SOD91965.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A286G8Z4; -.
DR   OrthoDB; 9758568at2; -.
DR   Proteomes; UP000219621; Unassembled WGS sequence.
DR   GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR   GO; GO:0004176; F:ATP-dependent peptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0004252; F:serine-type endopeptidase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0030163; P:protein catabolic process; IEA:InterPro.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.8.60; -; 1.
DR   Gene3D; 3.30.230.10; -; 1.
DR   Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR   InterPro; IPR041699; AAA_32.
DR   InterPro; IPR046844; Lon-like_helical.
DR   InterPro; IPR008269; Lon_proteolytic.
DR   InterPro; IPR027065; Lon_Prtase.
DR   InterPro; IPR046843; LonB_AAA-LID.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR   InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR   PANTHER; PTHR10046:SF46; ARCHAEAL LON PROTEASE; 1.
DR   PANTHER; PTHR10046; ATP DEPENDENT LON PROTEASE FAMILY MEMBER; 1.
DR   Pfam; PF13654; AAA_32; 1.
DR   Pfam; PF05362; Lon_C; 1.
DR   Pfam; PF20436; LonB_AAA-LID; 1.
DR   Pfam; PF20437; LonC_helical; 1.
DR   PRINTS; PR00830; ENDOLAPTASE.
DR   SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR   SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR   PROSITE; PS51786; LON_PROTEOLYTIC; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000256|PROSITE-ProRule:PRU01122};
KW   Protease {ECO:0000256|ARBA:ARBA00022670, ECO:0000256|PROSITE-
KW   ProRule:PRU01122}; Reference proteome {ECO:0000313|Proteomes:UP000219621};
KW   Serine protease {ECO:0000256|PROSITE-ProRule:PRU01122}.
FT   DOMAIN          568..763
FT                   /note="Lon proteolytic"
FT                   /evidence="ECO:0000259|PROSITE:PS51786"
FT   ACT_SITE        658
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
FT   ACT_SITE        701
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU01122"
SQ   SEQUENCE   811 AA;  89891 MW;  A5B7F208FE7D046C CRC64;
     MPLDPLPADR LHTPCREADL PFETTAELPD QEDTVGQERA VEAVRFGIGI RADGYNIFAA
     GPQGTGKSSL VRQFIGRAAA AQPRPDDWCY VHNFDDPQRP RALRLPAGRG RAFQRAMERL
     VEELQAAIPA AFEADDYRAR RQAIEDEFKE RQERTFGEVQ TKARARGVAL VRTPVALALA
     PLKDGEVLSP DEFEKLSEDE RADRKQAMEE LQEDLQTRMR EIPKWEKEQR ERVRELDRDV
     TEYAVGHLID DLRADYEDCP AVLAHLDTVR KNLVERVDQF LPESEELRQL PPQIRKQLGG
     NREETHEQYK VNVVIGRHEN GGAPVVEEDH PSQPNLVGRI EHQQRYGALV TNFTLIRPGA
     LHRANGGYLV LDARKLLMQP FAYEDLKRAL RTREIRIEAP GASFGIFTTT SLEPEPIPLD
     VKVVLIGEPM VYYLLSHHDP EFRELFKVQA DFDYRMHRRD DTTLALARLV GTMARRDGLR
     PLDRSAVARV IDHAARLADD SERLTTHMGS VADLVREADF WAGERGAEVV SRRDVQQAID
     AKTYRTDRVR EHIQEEFARG TLMVDTDGEK AGQINGLAVL QLGTFAFGRP SRITCRVRMG
     RGELVDIERE VGTGGELHTK GVLILSGFLA ARFGQDGPLS VSASLVFEQS YGLIDGDSAS
     CAELYALLSA LADVPIRQGF AVTGSVNQFG EVQPIGGVNE KIEGFFDVCA ARGLTGDQGV
     LIPASNVKNL MLRPDVVEAA AAGRFHIHAV STVDEGIEIL TGIPAGAPDD GAGWPTGSIN
     RRVAARLAQW RRRALELSAA GSGRNGNGGR G
//