ID   A0A286GJ05_9ACTN        Unreviewed;       668 AA.
AC   A0A286GJ05;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   24-JAN-2024, entry version 26.
DE   SubName: Full=Putative peptidoglycan lipid II flippase {ECO:0000313|EMBL:SOD95513.1};
GN   ORFNames=SAMN06272739_1236 {ECO:0000313|EMBL:SOD95513.1};
OS   Blastococcus haudaquaticus.
OC   Bacteria; Actinomycetota; Actinomycetes; Geodermatophilales;
OC   Geodermatophilaceae; Blastococcus.
OX   NCBI_TaxID=1938745 {ECO:0000313|EMBL:SOD95513.1, ECO:0000313|Proteomes:UP000219482};
RN   [1] {ECO:0000313|Proteomes:UP000219482}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 44270 {ECO:0000313|Proteomes:UP000219482};
RA   Varghese N., Submissions S.;
RL   Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC   -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141}; Multi-
CC       pass membrane protein {ECO:0000256|ARBA:ARBA00004141}.
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DR   EMBL; OCNK01000001; SOD95513.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A286GJ05; -.
DR   Proteomes; UP000219482; Unassembled WGS sequence.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
DR   GO; GO:0009252; P:peptidoglycan biosynthetic process; IEA:UniProtKB-KW.
DR   GO; GO:0008360; P:regulation of cell shape; IEA:UniProtKB-KW.
DR   CDD; cd13123; MATE_MurJ_like; 1.
DR   InterPro; IPR004268; MurJ.
DR   NCBIfam; TIGR01695; murJ_mviN; 1.
DR   PANTHER; PTHR47019; LIPID II FLIPPASE MURJ; 1.
DR   PANTHER; PTHR47019:SF1; LIPID II FLIPPASE MURJ; 1.
DR   Pfam; PF03023; MurJ; 1.
DR   PRINTS; PR01806; VIRFACTRMVIN.
PE   4: Predicted;
KW   Cell membrane {ECO:0000256|ARBA:ARBA00022475};
KW   Cell shape {ECO:0000256|ARBA:ARBA00022960};
KW   Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW   Peptidoglycan synthesis {ECO:0000256|ARBA:ARBA00022984};
KW   Reference proteome {ECO:0000313|Proteomes:UP000219482};
KW   Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW   ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        160..179
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        185..204
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        224..244
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        264..283
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        295..314
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        329..351
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        372..393
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        413..434
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        462..484
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        496..519
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        531..550
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        556..574
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        595..613
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        625..649
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   REGION          1..93
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          112..134
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        19..48
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        62..93
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   668 AA;  68194 MW;  62E084F4C1D6FDF6 CRC64;
     MTAGPDDRPA ADEVRAGRPP VPPATPRPQR RPGGPSLPPP PYRATPPPSA PFADQGSGGA
     PSGQPPVPPP VPRPSAAARP PARPLPPLPP LRNRWVPAAD DNFTQVITVL PPVPRGPVAE
     TEEEADQREG APGAAGGILR AAGTMAVATL VSRITGLLRT MVLAAALGVT LVADAYTTAN
     TLPNIVYELL LGGVLSSVVV PLLVHAQERD ADGGVAYTQR LATIAVAALT LVTALAVLAA
     PFLTRLAGIS DDPGQVELGT WLTRILLVEV VFYGIGALAQ AVLNSRGVFG PPAWAPVLNN
     VVVIATGALF LAASDPLDLT PTTITPGQVW LLGIGTTLGI AVQALVLLPL LGKAGVPLRP
     RWGFRETGLR EAGTLGLWVV GYSAVSALGV VVATRIANAA TREGGLGSTA FSYASLLFQM
     PYGIIGVALL TALLPRMSRA AARSDVTGVT DDLSLGTRLS ALGLLPVTAA LVVLGPPIGV
     LAFARGNTSL EEAAAIGTAL AVGAFGLLPM AVTLLQLRVF YAMKDARTPT LIQIGMVAVR
     VPLLLLVPTV VDPEHVVAGL MLVTGITYVA GWVIGDVALR RKLGGRRSGA TLGPLLRMTA
     VAVVAGGAGL LVRNVTDDLV GTSPAGSLVT VLVGTVVIGG VALAGLVIAR VPEVREPLAA
     LRTRKGRG
//