ID A0A286IJM2_9BACT Unreviewed; 948 AA.
AC A0A286IJM2;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=UvrABC system protein A {ECO:0000256|ARBA:ARBA00039316};
DE AltName: Full=Excinuclease ABC subunit A {ECO:0000256|ARBA:ARBA00042156};
GN ORFNames=SAMN06298216_1255 {ECO:0000313|EMBL:SOE20774.1};
OS Spirosomataceae bacterium TFI 002.
OC Bacteria; Bacteroidota; Cytophagia; Cytophagales; Spirosomataceae.
OX NCBI_TaxID=1945892 {ECO:0000313|EMBL:SOE20774.1, ECO:0000313|Proteomes:UP000217493};
RN [1] {ECO:0000313|EMBL:SOE20774.1, ECO:0000313|Proteomes:UP000217493}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=TFI 002 {ECO:0000313|EMBL:SOE20774.1,
RC ECO:0000313|Proteomes:UP000217493};
RA Ehlers B., Leendertz F.H.;
RL Submitted (SEP-2017) to the EMBL/GenBank/DDBJ databases.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000256|ARBA:ARBA00004496}.
CC -!- SIMILARITY: Belongs to the ABC transporter superfamily. UvrA family.
CC {ECO:0000256|ARBA:ARBA00038000}.
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DR EMBL; LT907983; SOE20774.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A286IJM2; -.
DR Proteomes; UP000217493; Chromosome i.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0009380; C:excinuclease repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0004518; F:nuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0006289; P:nucleotide-excision repair; IEA:InterPro.
DR CDD; cd03271; ABC_UvrA_II; 1.
DR Gene3D; 1.10.8.280; ABC transporter ATPase domain-like; 1.
DR Gene3D; 1.20.1580.10; ABC transporter ATPase like domain; 2.
DR Gene3D; 3.30.1490.20; ATP-grasp fold, A domain; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR003439; ABC_transporter-like_ATP-bd.
DR InterPro; IPR017871; ABC_transporter-like_CS.
DR InterPro; IPR013815; ATP_grasp_subdomain_1.
DR InterPro; IPR027417; P-loop_NTPase.
DR InterPro; IPR004602; UvrA.
DR InterPro; IPR041552; UvrA_DNA-bd.
DR InterPro; IPR041102; UvrA_inter.
DR NCBIfam; TIGR00630; uvra; 1.
DR PANTHER; PTHR43152; UVRABC SYSTEM PROTEIN A; 1.
DR PANTHER; PTHR43152:SF3; UVRABC SYSTEM PROTEIN A; 1.
DR Pfam; PF17755; UvrA_DNA-bind; 1.
DR Pfam; PF17760; UvrA_inter; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 2.
DR PROSITE; PS00211; ABC_TRANSPORTER_1; 2.
DR PROSITE; PS50893; ABC_TRANSPORTER_2; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW DNA excision {ECO:0000256|ARBA:ARBA00022769};
KW DNA repair {ECO:0000256|ARBA:ARBA00023204};
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Excision nuclease {ECO:0000256|ARBA:ARBA00022881};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000217493};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771}.
FT DOMAIN 614..942
FT /note="ABC transporter"
FT /evidence="ECO:0000259|PROSITE:PS50893"
SQ SEQUENCE 948 AA; 106085 MW; CB6B4B688DAF8C25 CRC64;
MATKQLNDVQ LTGHDIIEVL GAREHNLKNI DVEIPRNKLV VITGISGSGK SSLAFDTIYA
EGQRRYMESF SAYARSFIGD MERPDVDKIN GLSPVISIEQ KTTSKNPRST VGTTTEIYDF
LRLLFARAGK AYSYVTGKPM IKQSQDQIVD QIFSDYENKK VSLLSPVVKG RKGHYRELFV
QIRKMGYTKV RVDGEVQDLV PKMQLDRYKI HDIEIVIDRI IPKKEDRYRV SQSVGTALKV
GKGSMLLMNE AEDIQYLSQN LMDPESGISY EEPSPNSFSF NSPYGACQTC NGLGQVEEIT
EESIIPDKTL SISRGGIVAL GDYRDLWIFK QISVILKKYK VSISTPIEKI PEEAMQTILY
GSDEPVAVPS KKNPGEKWDT KFEGIINFLK RQQENDNDKI QDWLQDFMLI KTCPDCQGER
LKIESRHFRI GDKNIAQLAD MDISDLAPWF DSVEEKLDNK QQQIAKEILK EIRKRIGFLF
GIGLDYLTLN RPLKTLSGGE AQRIRLATQI GTQLVGVLYI MDEPSIGLHQ RDNVKLIKAL
KDLRDLGNTV LVVEHDKDMM LQSDYILDIG PGAGRHGGKI VGKGTPEDFL KAGGITSDYL
ADRVKIEIPE RRKGNGNNLK ISGAVGHNLK NVTLNLPLGQ MICVTGVSGS GKSSLIHDTL
FPILNHHFFR AKREPLEYKK VTGLEHIDKV IEVDQSPIGR TPRSNPATYT GMFTDIRALF
SELPESKIRG YKPGRFSFNV KGGRCETCQG AGKKKIEMDF LPDVHVDCET CKGKRFNRET
LEVRYKGKSI ADVLDMTVET AMVFFESIPR VQRRVQILFE VGLGYITLGQ HATTLSGGEA
QRVKLSEELS KKDTGQTLYI LDEPTTGLHF SDIKKLMDVL QRLTDKGNTV LIIEHNLDVI
KVADHIIDLG PEGGSKGGLI IAEGTPEQVA KVKGSYTGFF LKKELAGK
//
