ID   A0A286U3F0_9BACT        Unreviewed;       800 AA.
AC   A0A286U3F0;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   SubName: Full=Adenylate cyclase, family 3 {ECO:0000313|EMBL:GAX62656.1};
GN   ORFNames=SCALIN_C38_0019 {ECO:0000313|EMBL:GAX62656.1};
OS   Candidatus Scalindua japonica.
OC   Bacteria; Planctomycetota; Candidatus Brocadiia; Candidatus Brocadiales;
OC   Candidatus Scalinduaceae; Scalindua.
OX   NCBI_TaxID=1284222 {ECO:0000313|EMBL:GAX62656.1, ECO:0000313|Proteomes:UP000218542};
RN   [1] {ECO:0000313|Proteomes:UP000218542}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=husup-a2 {ECO:0000313|Proteomes:UP000218542};
RA   Oshiki M., Mizuto K., Kimura Z., Kindaichi T., Satoh H., Okabe S.;
RT   "Genetic Diversity of Marine Anaerobic Ammonium-Oxidizing Bacteria as
RT   Revealed by Genomic and Proteomic Analyses of 'Candidatus Scalindua
RT   japonica'.";
RL   Environ. Microbiol. Rep. 0:0-0(2017).
CC   -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC       whole genome shotgun (WGS) entry which is preliminary data.
CC       {ECO:0000313|EMBL:GAX62656.1}.
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DR   EMBL; BAOS01000038; GAX62656.1; -; Genomic_DNA.
DR   AlphaFoldDB; A0A286U3F0; -.
DR   OrthoDB; 9806704at2; -.
DR   Proteomes; UP000218542; Unassembled WGS sequence.
DR   GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR   GO; GO:0004016; F:adenylate cyclase activity; IEA:UniProt.
DR   GO; GO:0009190; P:cyclic nucleotide biosynthetic process; IEA:InterPro.
DR   GO; GO:0035556; P:intracellular signal transduction; IEA:InterPro.
DR   CDD; cd07302; CHD; 1.
DR   Gene3D; 3.30.70.1230; Nucleotide cyclase; 1.
DR   InterPro; IPR001054; A/G_cyclase.
DR   InterPro; IPR007890; CHASE2.
DR   InterPro; IPR029787; Nucleotide_cyclase.
DR   InterPro; IPR011990; TPR-like_helical_dom_sf.
DR   InterPro; IPR019734; TPR_repeat.
DR   PANTHER; PTHR43081:SF16; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC; 1.
DR   PANTHER; PTHR43081; ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED; 1.
DR   Pfam; PF05226; CHASE2; 1.
DR   Pfam; PF00211; Guanylate_cyc; 1.
DR   SMART; SM01080; CHASE2; 1.
DR   SMART; SM00044; CYCc; 1.
DR   SUPFAM; SSF55073; Nucleotide cyclase; 1.
DR   SUPFAM; SSF48452; TPR-like; 1.
DR   PROSITE; PS50125; GUANYLATE_CYCLASE_2; 1.
DR   PROSITE; PS50005; TPR; 1.
PE   4: Predicted;
KW   Membrane {ECO:0000256|SAM:Phobius};
KW   Reference proteome {ECO:0000313|Proteomes:UP000218542};
KW   TPR repeat {ECO:0000256|PROSITE-ProRule:PRU00339};
KW   Transmembrane {ECO:0000256|SAM:Phobius};
KW   Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT   TRANSMEM        12..32
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        452..470
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   TRANSMEM        482..502
FT                   /note="Helical"
FT                   /evidence="ECO:0000256|SAM:Phobius"
FT   DOMAIN          544..676
FT                   /note="Guanylate cyclase"
FT                   /evidence="ECO:0000259|PROSITE:PS50125"
FT   REPEAT          736..769
FT                   /note="TPR"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00339"
SQ   SEQUENCE   800 AA;  91267 MW;  BE9E8CB66A287F13 CRC64;
     MSFIKSIKPG KKTISILISI FILIIVITIY NLEDRDTFKL LRIFKAIEQK SMDMRFQIRG
     KRDTGDEIVI VAIDENSIEK LGRYPWSRRY IAELVDKVSA AKAKLLALDV IYSEEQNTDI
     LKTFDILTRD YNESPLWKNL PEETDKEQFL SALYEKRKTF DEDSRLKEAF RRAVMDSGMD
     IISAIDFVYM TQRNTTGFTG KEVSSLGKEL LKESAYFPVL VGGDISSKKK SPDGNQLTVL
     TSKNRKEIMN NILALYRPKT AVGVINMIDP FAEWVTYQGF VDTNVDYSGI VRSEYMAIHF
     ENEFYPPLGV QAARIYKNID YGELKLVLTE KLVFKETEIP IDSWNRMMIN YCGPESTFKY
     FSFCDVIEGK VSPDAFNNKI VFLGATAFGL GDYIATPFSS QTPGVEKHAT ITENILHEKF
     VVRGEWEVLH DIIAIICISL VMGIVLPLLP SIWGAVASIF LWAGYYYYVY ERFVNDGTWL
     NVTYPGITII ICFSSIILYR FMSEEKLRKG VKTAFENFMD PKVVHEILKE PEDIKLGGEE
     REVTVYFSDI EKFSSISEKL KPSELIELLN EYLSEMTDQI LGYGGFLDKY IGDAIVAAFG
     TPLEQPDHAL KACLASIDNQ KRICELNTKF KKEGRLQIKA RIGLNTGRVL VGNVGSTNRL
     SYTVIGDEVN LGARLEAANK YYGTYTMISE RTYELASDHI EARELDMIRV IGKKKPVKVY
     ELIGRKGEIS NAKRIVLELY EEGLIAYKKK EWQNAIDMFQ KAVVKVPHDG PALTYLERCK
     AYTQNPPPEN WDGVYILTEK
//