ID A0A286UP18_9AGAM Unreviewed; 824 AA.
AC A0A286UP18;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 24-JAN-2024, entry version 25.
DE SubName: Full=Mismatch repair-related protein {ECO:0000313|EMBL:PAV21351.1};
GN ORFNames=PNOK_0397800 {ECO:0000313|EMBL:PAV21351.1};
OS Pyrrhoderma noxium.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Hymenochaetales; Hymenochaetaceae; Pyrrhoderma.
OX NCBI_TaxID=2282107 {ECO:0000313|EMBL:PAV21351.1, ECO:0000313|Proteomes:UP000217199};
RN [1] {ECO:0000313|Proteomes:UP000217199}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FFPRI411160 {ECO:0000313|Proteomes:UP000217199};
RA Chung C.-L., Lee J.T., Akiba M., Lee H.-H., Kuo T.-H., Liu D., Ke H.-M.,
RA Yokoi T., Roa M.B., Lu M.J., Chang Y.-Y., Ann P.-J., Tsai J.-N.,
RA Chen C.-Y., Tzean S.-S., Ota Y., Hattori T., Sahashi N., Liou R.-F.,
RA Kikuchi T., Tsai I.J.;
RT "The Genomic Landscape Of Tree Rot In Phellinus noxius And Its
RT Hymenochaetales Members.";
RL bioRxiv 0:0-0(2017).
CC -!- SIMILARITY: Belongs to the DNA mismatch repair MutL/HexB family.
CC {ECO:0000256|ARBA:ARBA00006082}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV21351.1}.
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DR EMBL; NBII01000003; PAV21351.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A286UP18; -.
DR STRING; 2282107.A0A286UP18; -.
DR InParanoid; A0A286UP18; -.
DR OrthoDB; 9570at2759; -.
DR Proteomes; UP000217199; Chromosome 3.
DR GO; GO:0032300; C:mismatch repair complex; IEA:InterPro.
DR GO; GO:0005524; F:ATP binding; IEA:InterPro.
DR GO; GO:0016887; F:ATP hydrolysis activity; IEA:InterPro.
DR GO; GO:0140664; F:ATP-dependent DNA damage sensor activity; IEA:InterPro.
DR GO; GO:0030983; F:mismatched DNA binding; IEA:InterPro.
DR GO; GO:0061982; P:meiosis I cell cycle process; IEA:UniProt.
DR GO; GO:0006298; P:mismatch repair; IEA:InterPro.
DR Gene3D; 3.30.230.10; -; 1.
DR Gene3D; 3.30.565.10; Histidine kinase-like ATPase, C-terminal domain; 1.
DR Gene3D; 3.30.1540.20; MutL, C-terminal domain, dimerisation subdomain; 1.
DR Gene3D; 3.30.1370.100; MutL, C-terminal domain, regulatory subdomain; 1.
DR InterPro; IPR014762; DNA_mismatch_repair_CS.
DR InterPro; IPR013507; DNA_mismatch_S5_2-like.
DR InterPro; IPR036890; HATPase_C_sf.
DR InterPro; IPR038973; MutL/Mlh/Pms-like.
DR InterPro; IPR014790; MutL_C.
DR InterPro; IPR042120; MutL_C_dimsub.
DR InterPro; IPR042121; MutL_C_regsub.
DR InterPro; IPR037198; MutL_C_sf.
DR InterPro; IPR020568; Ribosomal_Su5_D2-typ_SF.
DR InterPro; IPR014721; Ribsml_uS5_D2-typ_fold_subgr.
DR PANTHER; PTHR10073; DNA MISMATCH REPAIR PROTEIN MLH, PMS, MUTL; 1.
DR PANTHER; PTHR10073:SF47; DNA MISMATCH REPAIR PROTEIN MLH3; 1.
DR Pfam; PF01119; DNA_mis_repair; 2.
DR Pfam; PF13589; HATPase_c_3; 1.
DR SMART; SM01340; DNA_mis_repair; 1.
DR SMART; SM00853; MutL_C; 1.
DR SUPFAM; SSF55874; ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase; 1.
DR SUPFAM; SSF118116; DNA mismatch repair protein MutL; 1.
DR SUPFAM; SSF54211; Ribosomal protein S5 domain 2-like; 1.
DR PROSITE; PS00058; DNA_MISMATCH_REPAIR_1; 1.
PE 3: Inferred from homology;
KW DNA damage {ECO:0000256|ARBA:ARBA00022763};
KW Reference proteome {ECO:0000313|Proteomes:UP000217199}.
FT DOMAIN 229..367
FT /note="DNA mismatch repair protein S5"
FT /evidence="ECO:0000259|SMART:SM01340"
FT DOMAIN 555..763
FT /note="MutL C-terminal dimerisation"
FT /evidence="ECO:0000259|SMART:SM00853"
FT REGION 376..418
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 454..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 824 AA; 92299 MW; 315D4F20A04AB73E CRC64;
MSSSARLERL DSATRSKLRS TQILTSLPQI ISELAQNSID ANADTIEVGL YQDEWSCWVR
DNGTGISKDG FDLLRQGLEK GRYLSSKTYD PTSLDHANTF GFRGEALASA ADLSCIEISS
RTSRSKESWS IILKGGEQLY YGPSTRWRRE SSGTSVLLRD VFFNLPVRRL SHPSPSRTIE
LIKRELEQLA LMHPGISFSL KDESKELSTV PERSRVLVIP KTASALATFK ALYGRVLVEH
VNEINEESGQ MKLEGFISLV GSQSKSYQFI FVNRHIVDHG ELHRILDKRF TASTFSKHAL
DESGDVPPTR MRRSPRKGDR HPIYVLSLTL PPKEIDNCLD PSKAVIKFQK QTDVINFFTD
IIQRFLARNG FSSKRPSTDN RFTFSSKRNM KRRRTSSGTH QNGAPWSPKN GKVTKKSKPS
DVFISEDQQN DPSEEFTWLD PNTGKAYIID TRTGHSFQPS KSPTKGLLIT SSNHNVSSQK
DMPEWIRKAL MANKAYAATE PSIPVYDANL FESSPRKESW IREFASSAST HTTLENIQNI
PNPSFSKDIL GTAKVITQVD RKFIACIIQN TSVTQTSSES ENFSGKTLLL IDQHAADERI
RVEKYLKSLC FGHLRDGGLG IERRILDPPV PVLLTEHELE KMNSEEANVA FRSWGFDIFR
EGTKGGSLYE EGFGMIRFSS VPEVVADKLL SGSCDNLHEV TKGYLAKLET ESLGYRMKDL
SIQETGKEDE NNWLRALRDC PRELVNLINS RACRGAIMFN DVLTVDQCVR LVQELSVTAY
PFQCAHGRPS VVPLISLQGR RESGGSGLAA QQPSSKAINW GALL
//
