ID A0A286UXQ8_9AGAM Unreviewed; 1238 AA.
AC A0A286UXQ8;
DT 31-JAN-2018, integrated into UniProtKB/TrEMBL.
DT 31-JAN-2018, sequence version 1.
DT 27-MAR-2024, entry version 23.
DE RecName: Full=RNA helicase {ECO:0000256|ARBA:ARBA00012552};
DE EC=3.6.4.13 {ECO:0000256|ARBA:ARBA00012552};
GN ORFNames=PNOK_0144500 {ECO:0000313|EMBL:PAV24377.1};
OS Pyrrhoderma noxium.
OC Eukaryota; Fungi; Dikarya; Basidiomycota; Agaricomycotina; Agaricomycetes;
OC Hymenochaetales; Hymenochaetaceae; Pyrrhoderma.
OX NCBI_TaxID=2282107 {ECO:0000313|EMBL:PAV24377.1, ECO:0000313|Proteomes:UP000217199};
RN [1] {ECO:0000313|Proteomes:UP000217199}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FFPRI411160 {ECO:0000313|Proteomes:UP000217199};
RA Chung C.-L., Lee J.T., Akiba M., Lee H.-H., Kuo T.-H., Liu D., Ke H.-M.,
RA Yokoi T., Roa M.B., Lu M.J., Chang Y.-Y., Ann P.-J., Tsai J.-N.,
RA Chen C.-Y., Tzean S.-S., Ota Y., Hattori T., Sahashi N., Liou R.-F.,
RA Kikuchi T., Tsai I.J.;
RT "The Genomic Landscape Of Tree Rot In Phellinus noxius And Its
RT Hymenochaetales Members.";
RL bioRxiv 0:0-0(2017).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + H2O = ADP + H(+) + phosphate; Xref=Rhea:RHEA:13065,
CC ChEBI:CHEBI:15377, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:43474, ChEBI:CHEBI:456216; EC=3.6.4.13;
CC Evidence={ECO:0000256|ARBA:ARBA00001556};
CC -!- SIMILARITY: Belongs to the DEAD box helicase family. DEAH subfamily.
CC PRP16 sub-subfamily. {ECO:0000256|ARBA:ARBA00038040}.
CC -!- CAUTION: The sequence shown here is derived from an EMBL/GenBank/DDBJ
CC whole genome shotgun (WGS) entry which is preliminary data.
CC {ECO:0000313|EMBL:PAV24377.1}.
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DR EMBL; NBII01000001; PAV24377.1; -; Genomic_DNA.
DR AlphaFoldDB; A0A286UXQ8; -.
DR STRING; 2282107.A0A286UXQ8; -.
DR InParanoid; A0A286UXQ8; -.
DR OrthoDB; 3682876at2759; -.
DR Proteomes; UP000217199; Chromosome 1.
DR GO; GO:1990904; C:ribonucleoprotein complex; IEA:UniProt.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0016787; F:hydrolase activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR CDD; cd18791; SF2_C_RHA; 1.
DR Gene3D; 1.20.120.1080; -; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 2.
DR InterPro; IPR011709; DEAD-box_helicase_OB_fold.
DR InterPro; IPR011545; DEAD/DEAH_box_helicase_dom.
DR InterPro; IPR002464; DNA/RNA_helicase_DEAH_CS.
DR InterPro; IPR048333; HA2_WH.
DR InterPro; IPR007502; Helicase-assoc_dom.
DR InterPro; IPR014001; Helicase_ATP-bd.
DR InterPro; IPR001650; Helicase_C.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR18934; ATP-DEPENDENT RNA HELICASE; 1.
DR PANTHER; PTHR18934:SF91; PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16; 1.
DR Pfam; PF00270; DEAD; 1.
DR Pfam; PF21010; HA2_C; 1.
DR Pfam; PF04408; HA2_N; 1.
DR Pfam; PF00271; Helicase_C; 1.
DR Pfam; PF07717; OB_NTP_bind; 1.
DR SMART; SM00487; DEXDc; 1.
DR SMART; SM00847; HA2; 1.
DR SMART; SM00490; HELICc; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS00690; DEAH_ATP_HELICASE; 1.
DR PROSITE; PS51192; HELICASE_ATP_BIND_1; 1.
DR PROSITE; PS51194; HELICASE_CTER; 1.
PE 3: Inferred from homology;
KW ATP-binding {ECO:0000256|ARBA:ARBA00022840};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022801};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000217199}.
FT DOMAIN 575..738
FT /note="Helicase ATP-binding"
FT /evidence="ECO:0000259|PROSITE:PS51192"
FT DOMAIN 729..906
FT /note="Helicase C-terminal"
FT /evidence="ECO:0000259|PROSITE:PS51194"
FT REGION 146..328
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1185..1238
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 146..168
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 201..278
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1202..1217
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1238 AA; 138026 MW; 469E090446F8FCC1 CRC64;
MAAPVTQSEI QDAFVHELAI KLSRALNTIN PNDLLARRVI DIAKNNSEQG FIQASKGFGK
FKDSFLSEIH SEILSHAKQE ASGHIPEPVK GITVIDSDVL EPDPIRQGGL VRKDIQHKFR
APAKPIEPPT PRTSVLGLDR LAKEKRAAAS ALENDNARNK RSRGENGRND AMFKVPTLPA
SRSSNIRQRG EETPSHPGGL SETARHKRDE FRRNREKQRE GWKVKEEQRE DAPRGLGDFQ
RRSNRDRAWG GRGRMHEDDR SRGSGWTPRS ERGQGRDDGP SVRIPNARWD STPRADRAGE
DGSWGSARSR GWDAPTPRVS RGASPDGDGA FGIDVHEWEE EQVRLDRDWY MGAEEGGLAG
DEEHNPLSAY NDLEQLKQLE IANKQVKKKI SAKQAQYNAD NDLWEANRMV TSGVATRKAL
DLDFEDDSES TVHVMVHDLK PPFLDGRTVF TKQLEPVNPI RDPTSDLAVF AKKGSALVKE
KREQAERAKA AAKLTSLGGT SLGNIMGVRD EEADAEAAAD AKANASGGDK EDYKGESKFA
SHLKAGTAAS SFAKSRTLKE QREYLPAFAC REDLLRVIRD NQVIVVVGET GSGKTTQLTQ
FLYEDGYCNS GIIGCTQPRR VAAMSVAKRV SEEMECKLGD KVGYAIRFED CTSSQTVIKY
MTDGVLLRES LNEGDLDRYS VIVLDEAHER SLSTDVLMGL LRKILSRRRD LKLIVTSATM
NAEKFSNFYG NAPCYTIPGR TFPVEVFHAK SPCQEDIEIT CQVVQERLDQ LDDPPSLAVL
PIYSQMPADL QAKIFEATDD GRRKVIVATN IAETSLTVDG ILYVVDAGYC KLKVYNSKVG
MDALQITPIS QANANQRTGR AGRTGAGFCY RLYTEMAFRN ELFPNTIPEI QRTNLANTVL
LLKSLGVKNL LEFDFMDPPP QANILNSMYQ LWVLGALDNA GDLTPVGRKM SEFPMEPSMA
KMLIASVEYG CSAEMLTIVS MLSVPSVFYR PKERMEEADA AREKFAVPES DHLTLLNVYG
QWKSHGYRDE WAMRHFLHPK LLRKAREVRT QLEDIMKMQK MSIVSAGTDF DIMRKAITAG
YFHQAARVKG IGEFVNIRTG LPTHLHPTSA LYGLGYTPTY VVYHELILTS KEYMTQVTAV
DAYWLAELGS VFYSVKEKNF DDRGMQRKAD REFSKRAELE MEMAKQREEN KRKEQEEAVM
AAQTAATRST SNIIVPGTPR TGGAGSRLGQ TPRRRAGL
//
