ID A0A286X7K7_CAVPO Unreviewed; 86 AA.
AC A0A286X7K7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE RecName: Full=Triple QxxK/R motif-containing protein {ECO:0000256|ARBA:ARBA00014257};
GN Name=TRIQK {ECO:0000313|Ensembl:ENSCPOP00000021405.1};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000021405.1, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000021405.1}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000021405.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Endoplasmic reticulum membrane
CC {ECO:0000256|ARBA:ARBA00004389}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004389}. Membrane
CC {ECO:0000256|ARBA:ARBA00004167}; Single-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004167}.
CC -!- SIMILARITY: Belongs to the TRIQK family.
CC {ECO:0000256|ARBA:ARBA00007709}.
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DR EMBL; AAKN02000447; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003480010.1; XM_003479962.3.
DR RefSeq; XP_012999171.1; XM_013143717.1.
DR RefSeq; XP_012999172.1; XM_013143718.1.
DR AlphaFoldDB; A0A286X7K7; -.
DR Ensembl; ENSCPOT00000045523.1; ENSCPOP00000021405.1; ENSCPOG00000031688.1.
DR GeneID; 100723611; -.
DR KEGG; cpoc:100723611; -.
DR CTD; 286144; -.
DR VEuPathDB; HostDB:ENSCPOG00000031688; -.
DR eggNOG; ENOG502S3QR; Eukaryota.
DR GeneTree; ENSGT00390000017350; -.
DR InParanoid; A0A286X7K7; -.
DR OMA; NIGKQDY; -.
DR OrthoDB; 3036655at2759; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000031688; Expressed in heart left ventricle and 12 other cell types or tissues.
DR GO; GO:0005789; C:endoplasmic reticulum membrane; IEA:InterPro.
DR InterPro; IPR024842; TRIQK.
DR PANTHER; PTHR20583; TRIPLE QXXK/R MOTIF-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR20583:SF1; TRIPLE QXXK_R MOTIF-CONTAINING PROTEIN; 1.
DR Pfam; PF15168; TRIQK; 1.
PE 3: Inferred from homology;
KW Endoplasmic reticulum {ECO:0000256|ARBA:ARBA00022824};
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005447};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692, ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|SAM:Phobius}.
FT TRANSMEM 51..71
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
SQ SEQUENCE 86 AA; 9613 MW; 9B2DAC1031FDE60E CRC64;
MGRKDASTTK LPVDQYRKQI GKQDYKKTKP ILRATKLKAE AKKTALGIKE VGLVLAAILA
LLLAFYAFFY LRLSSDAEPD LDPNED
//
