ID A0A286XVT6_CAVPO Unreviewed; 328 AA.
AC A0A286XVT6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 28.
DE SubName: Full=GTPase, IMAP family member 4 {ECO:0000313|Ensembl:ENSCPOP00000029585.1};
GN Name=GIMAP4 {ECO:0000313|Ensembl:ENSCPOP00000029585.1};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000029585.1, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000029585.1}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000029585.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like
CC GTPase superfamily. AIG1/Toc34/Toc159-like paraseptin GTPase family.
CC IAN subfamily. {ECO:0000256|ARBA:ARBA00008535}.
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DR EMBL; AAKN02032921; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A286XVT6; -.
DR STRING; 10141.ENSCPOP00000029585; -.
DR Ensembl; ENSCPOT00000044697.1; ENSCPOP00000029585.1; ENSCPOG00000037321.1.
DR VEuPathDB; HostDB:ENSCPOG00000037321; -.
DR GeneTree; ENSGT00940000159317; -.
DR InParanoid; A0A286XVT6; -.
DR OMA; YLMEAPE; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000037321; Expressed in adrenal gland and 9 other cell types or tissues.
DR GO; GO:0005829; C:cytosol; IEA:Ensembl.
DR GO; GO:0043231; C:intracellular membrane-bounded organelle; IEA:Ensembl.
DR GO; GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
DR CDD; cd01852; AIG1; 1.
DR Gene3D; 3.40.50.300; P-loop containing nucleotide triphosphate hydrolases; 1.
DR InterPro; IPR006703; G_AIG1.
DR InterPro; IPR045058; GIMA/IAN/Toc.
DR InterPro; IPR027417; P-loop_NTPase.
DR PANTHER; PTHR10903:SF170; GTPASE IMAP FAMILY MEMBER 4; 1.
DR PANTHER; PTHR10903; GTPASE, IMAP FAMILY MEMBER-RELATED; 1.
DR Pfam; PF04548; AIG1; 1.
DR SUPFAM; SSF52540; P-loop containing nucleoside triphosphate hydrolases; 1.
DR PROSITE; PS51720; G_AIG1; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleotide-binding {ECO:0000256|ARBA:ARBA00022741};
KW Reference proteome {ECO:0000313|Proteomes:UP000005447}.
FT DOMAIN 29..231
FT /note="AIG1-type G"
FT /evidence="ECO:0000259|PROSITE:PS51720"
FT COILED 242..290
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 328 AA; 38020 MW; 7BC349B4970BF338 CRC64;
MTRLCFFIYR NQTTMAAPYD GSGNQDCRNS QLRIVLLGKT GAGKSATGNS ILGEKAFSSG
IASKSITKAC QKSICTWNER EIVVVDTPGI FDTEAQDVDT RREIARCIQL TSPGPHALVL
VVPLGRYTEE ESKATEKILN MFGCRARRFT ILLFTRKDDL EGIDLGDYIM DAPERVQNLI
DRFDGRYCAF NNRAMGSEQE DQRNQLLTLV QRIVRENHGE CYTSELYQRT EEQIQKQIHL
VQEQCRAELE RVRAQLREEY EEKIRDLEDK LEQERRKAQM EKEIARRESL CIHRQQNARM
EVESQTSIIE FIIQTWNFVS LWISLFKD
//
