ID A0A286XX01_CAVPO Unreviewed; 1051 AA.
AC A0A286XX01;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Zinc finger protein 865 {ECO:0000313|Ensembl:ENSCPOP00000029990.1};
GN Name=ZNF865 {ECO:0000313|Ensembl:ENSCPOP00000029990.1};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000029990.1, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000029990.1}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000029990.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAKN02055570; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003461708.1; XM_003461660.3.
DR AlphaFoldDB; A0A286XX01; -.
DR STRING; 10141.ENSCPOP00000029990; -.
DR Ensembl; ENSCPOT00000036188.1; ENSCPOP00000029990.1; ENSCPOG00000040579.1.
DR GeneID; 100733273; -.
DR KEGG; cpoc:100733273; -.
DR CTD; 100507290; -.
DR VEuPathDB; HostDB:ENSCPOG00000040579; -.
DR GeneTree; ENSGT00530000064557; -.
DR InParanoid; A0A286XX01; -.
DR OMA; TPQWGIV; -.
DR OrthoDB; 4607663at2759; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000040579; Expressed in frontal cortex and 13 other cell types or tissues.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 17.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR24381:SF393; CHROMATIN-LINKED ADAPTOR FOR MSL PROTEINS, ISOFORM B-RELATED; 1.
DR PANTHER; PTHR24381; ZINC FINGER PROTEIN; 1.
DR Pfam; PF00096; zf-C2H2; 11.
DR Pfam; PF13912; zf-C2H2_6; 3.
DR SMART; SM00355; ZnF_C2H2; 20.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 11.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 20.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 20.
PE 4: Predicted;
KW Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Reference proteome {ECO:0000313|Proteomes:UP000005447};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00042};
KW Zinc-finger {ECO:0000256|PROSITE-ProRule:PRU00042}.
FT DOMAIN 217..244
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 245..272
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 345..372
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 373..400
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 402..429
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 436..463
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 544..571
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 572..599
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 600..627
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 664..691
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 692..719
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 784..811
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 812..839
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 840..867
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 868..895
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 896..923
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 924..951
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 952..979
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 981..1008
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 1009..1036
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT REGION 55..129
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 155..176
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 268..331
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 455..475
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 57..83
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 86..112
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 113..129
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 309..323
FT /note="Pro residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1051 AA; 109868 MW; 32248CC8AD9F3E62 CRC64;
MEGNPAGGGG SSGLGGEDGV HFQSYPFDFL EFLNHQRFEP MELYGEHAKA VAALPCAPGP
PLQPPPQPPP PQFDYPPPAS FKPKAEAPSS ASSSSSSSSS SSSSSTSSTQ SKKPDPPLPP
AFGAPPPPLF DAAFPAPQWG IVDLSGHQHL FGNLKRSGPA AGPAVAPGLG GPAGTPGPLP
VPPQTPPGPA AAGAACDPAK DDKGYFRRLK YLMERRFPCG VCQKSFKQSS HLVQHMLVHS
GERPYECGVC GRTYNHVSSL IRHRRCHKDA PATGAPPPPA SGAPLAPALG LAQGSAAPAS
TTAGVTPAPV GPPAAPAPPA DGSATPAPAG VAAPPVATAS GDGPFACPLC WKVFKKPSHL
HQHQIIHTGE KPFSCSVCSK SFNRRESLKR HVKTHSADLL RLPCGVCGKA FRDAAYLLKH
QAAHAGAAAG GARPAYACEL CGKSYSAPQS LLRHKAAHAP PPASEVPKDP AAPAVAPPTP
TFPAGPYLLP AEPPAGDSEK AAAAAAAVVY GAVPVPLLGA HPLLLGGPGA GGTGGSGAAA
AKTFCCGICG RGFGRRETLK RHERIHTGEK PHQCPVCGKR FRESFHLSKH HVVHTRERPY
KCELCGKVFG YPQSLTRHRQ VHRLQLPCAL AGAAGLPAAQ GAAGGCGAGA SGAGGAGPTD
TLSYACSDCG EHFPDLFHVM SHKEAHMSEK PYGCDACGKT FGFIENLMWH KLVHQAAPER
LLAPTGQQSS EGSGGTDAAL VLDNGLAGEV GAAVAALAGV SGGEDAGAAS TAAGGGAGAG
AERFSCATCG QSFKHFLGLV THKYVHLVRR TLGCGLCGQS FAGAYDLLLH RRSHRQKRGF
RCPVCGKRFW EAALLMRHQR CHTEQRPYRC GVCGRGFLRS WYLRQHRVVH TGERAFKCGV
CAKRFAQSSS LAEHRRLHAV ARPQRCGACG KTFRYRSNLL EHQRLHLGER AYRCEHCGKG
FFYLSSVLRH QRAHEPPRPE LRCPACLKAF KDPGYFRKHL AAHQGGRPFR CSSCGEGFAN
TYGLKKHRLV HKAEGLGAPG AGTGALAGKD A
//
