ID A0A286XXX8_CAVPO Unreviewed; 150 AA.
AC A0A286XXX8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE SubName: Full=Cell cycle exit and neuronal differentiation 1 {ECO:0000313|Ensembl:ENSCPOP00000030394.1};
GN Name=CEND1 {ECO:0000313|Ensembl:ENSCPOP00000030394.1};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000030394.1, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000030394.1}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000030394.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAKN02056355; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_004999573.1; XM_004999516.2.
DR AlphaFoldDB; A0A286XXX8; -.
DR STRING; 10141.ENSCPOP00000030394; -.
DR Ensembl; ENSCPOT00000031619.1; ENSCPOP00000030394.1; ENSCPOG00000038749.1.
DR GeneID; 100717503; -.
DR KEGG; cpoc:100717503; -.
DR CTD; 51286; -.
DR VEuPathDB; HostDB:ENSCPOG00000038749; -.
DR eggNOG; ENOG502SGTV; Eukaryota.
DR GeneTree; ENSGT00390000012831; -.
DR InParanoid; A0A286XXX8; -.
DR OMA; WSCENLN; -.
DR OrthoDB; 5146004at2759; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000038749; Expressed in cerebellum and 11 other cell types or tissues.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-KW.
DR GO; GO:0005739; C:mitochondrion; IEA:Ensembl.
DR GO; GO:0031982; C:vesicle; IEA:Ensembl.
DR GO; GO:0007628; P:adult walking behavior; IEA:Ensembl.
DR GO; GO:0021686; P:cerebellar granular layer maturation; IEA:Ensembl.
DR GO; GO:0021702; P:cerebellar Purkinje cell differentiation; IEA:Ensembl.
DR GO; GO:0021941; P:negative regulation of cerebellar granule cell precursor proliferation; IEA:Ensembl.
DR GO; GO:0021933; P:radial glia guided migration of cerebellar granule cell; IEA:Ensembl.
DR InterPro; IPR020162; Cend1.
DR PANTHER; PTHR36683; CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1; 1.
DR PANTHER; PTHR36683:SF1; CELL CYCLE EXIT AND NEURONAL DIFFERENTIATION PROTEIN 1; 1.
DR Pfam; PF15677; CEND1; 1.
PE 4: Predicted;
KW Membrane {ECO:0000256|SAM:Phobius};
KW Reference proteome {ECO:0000313|Proteomes:UP000005447};
KW Transmembrane {ECO:0000256|SAM:Phobius};
KW Transmembrane helix {ECO:0000256|SAM:Phobius}.
FT TRANSMEM 126..147
FT /note="Helical"
FT /evidence="ECO:0000256|SAM:Phobius"
FT REGION 1..120
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 150 AA; 15068 MW; CC0A57F797CB1A51 CRC64;
MESRAKLASS PKPDTKVSQA TAEAKAIPAA DGKVPSTKAG KKEAQVEKQE QPTTPASAKK
TTAKADPALL NNHSNLKPAP SAPAVPSSPD AAPEPKGPGD GAEEDESTTK CSGGKGPWPC
ENLTPLLVAG GVAVAAVALI LGVAFLARKK
//
