ID A0A286Y3R0_CAVPO Unreviewed; 468 AA.
AC A0A286Y3R0;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=General transcription factor IIA subunit 1 like {ECO:0000313|Ensembl:ENSCPOP00000032477.1};
GN Name=GTF2A1L {ECO:0000313|Ensembl:ENSCPOP00000032477.1};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000032477.1, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000032477.1}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000032477.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the TFIIA subunit 1 family.
CC {ECO:0000256|ARBA:ARBA00010059}.
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DR EMBL; AAKN02023986; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02023987; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; AAKN02023988; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR AlphaFoldDB; A0A286Y3R0; -.
DR STRING; 10141.ENSCPOP00000032477; -.
DR Ensembl; ENSCPOT00000041211.1; ENSCPOP00000032477.1; ENSCPOG00000033931.1.
DR VEuPathDB; HostDB:ENSCPOG00000033931; -.
DR GeneTree; ENSGT00940000163055; -.
DR InParanoid; A0A286Y3R0; -.
DR OMA; EDYDEEC; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000033931; Expressed in testis and 1 other cell type or tissue.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0001673; C:male germ cell nucleus; IEA:Ensembl.
DR GO; GO:0005672; C:transcription factor TFIIA complex; IEA:Ensembl.
DR GO; GO:0050890; P:cognition; IEA:Ensembl.
DR GO; GO:0006367; P:transcription initiation at RNA polymerase II promoter; IEA:InterPro.
DR CDD; cd07976; TFIIA_alpha_beta_like; 2.
DR Gene3D; 1.10.287.100; -; 1.
DR Gene3D; 2.30.18.10; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
DR InterPro; IPR004855; TFIIA_asu/bsu.
DR InterPro; IPR009088; TFIIA_b-brl.
DR PANTHER; PTHR12694:SF9; TFIIA-ALPHA AND BETA-LIKE FACTOR; 1.
DR PANTHER; PTHR12694; TRANSCRIPTION INITIATION FACTOR IIA SUBUNIT 1; 1.
DR Pfam; PF03153; TFIIA; 1.
DR SMART; SM01371; TFIIA; 1.
DR SUPFAM; SSF47396; Transcription factor IIA (TFIIA), alpha-helical domain; 1.
DR SUPFAM; SSF50784; Transcription factor IIA (TFIIA), beta-barrel domain; 1.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000005447};
KW Transcription {ECO:0000256|ARBA:ARBA00023163}.
FT REGION 292..321
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 377..417
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 468 AA; 50817 MW; 6E55690A56E2ADF3 CRC64;
MAGINPVPKL YKSIIEDVIE GVRDLFTEEG IEEHVLNDLK QLWETKVLQS KATEDFFGNS
IHSPLFTLQF PHTLHPTLQS TASLVIPANR TVPGFTTAEL GISNPSASFT FPGYPIYVPA
GVTFQTASGH LYKVNVPVMV AQTSGRPSVL QHPVQVFPQL GQPSVIQGSV PLLSPWCLPA
TPEKAPRMEA VFQQPTVLHS VPVDRKHLDS ATSGVFVPPG RELSQHGNSP CVQGPGVGFH
SRGSPVDSHV EPVLSVPARV TPHLRGGPVS ACPQGTLLHP VTDAQPHLPR HCRYGGDSAN
RPGEAAEPSS LPVSKENSNS RVDLTNQLTD DDINEIIQVD GTVDTSSNEE IGNIKDSEEN
EFLEIIDAGE LKVLEEEADS ISNEDSTANS SDNEGSQADI VEEDPLNSGD DVSEQDVPDL
FDTDNVIVCQ YDKIHRNKNK WKFYLKDGVM CFGGRDYVFA KAIGDAEW
//
