ID A0A286Y4E7_CAVPO Unreviewed; 218 AA.
AC A0A286Y4E7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE RecName: Full=DNA-directed RNA polymerase III subunit {ECO:0000256|PIRNR:PIRNR000777};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000032706.1, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000032706.1}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000032706.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- FUNCTION: DNA-dependent RNA polymerase catalyzes the transcription of
CC DNA into RNA using the four ribonucleoside triphosphates as substrates.
CC Specific peripheric component of RNA polymerase III which synthesizes
CC small RNAs, such as 5S rRNA and tRNAs. {ECO:0000256|PIRNR:PIRNR000777}.
CC -!- SUBUNIT: Component of the RNA polymerase III (Pol III) complex.
CC {ECO:0000256|PIRNR:PIRNR000777}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123,
CC ECO:0000256|PIRNR:PIRNR000777}.
CC -!- SIMILARITY: Belongs to the eukaryotic RPC7 RNA polymerase subunit
CC family. {ECO:0000256|ARBA:ARBA00008352, ECO:0000256|PIRNR:PIRNR000777}.
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DR EMBL; AAKN02004766; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003479340.1; XM_003479292.3.
DR RefSeq; XP_012998561.1; XM_013143107.1.
DR AlphaFoldDB; A0A286Y4E7; -.
DR STRING; 10141.ENSCPOP00000032706; -.
DR Ensembl; ENSCPOT00000036195.1; ENSCPOP00000032706.1; ENSCPOG00000030717.1.
DR GeneID; 100732525; -.
DR KEGG; cpoc:100732525; -.
DR CTD; 84265; -.
DR VEuPathDB; HostDB:ENSCPOG00000030717; -.
DR eggNOG; ENOG502QUPX; Eukaryota.
DR GeneTree; ENSGT01100000264660; -.
DR InParanoid; A0A286Y4E7; -.
DR OMA; KDLHAPF; -.
DR OrthoDB; 3038863at2759; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000030717; Expressed in pituitary gland and 13 other cell types or tissues.
DR GO; GO:0005666; C:RNA polymerase III complex; IEA:UniProtKB-UniRule.
DR GO; GO:0006383; P:transcription by RNA polymerase III; IEA:UniProtKB-UniRule.
DR InterPro; IPR024661; RNA_pol_III_Rpc31.
DR PANTHER; PTHR15367; DNA-DIRECTED RNA POLYMERASE III; 1.
DR PANTHER; PTHR15367:SF4; DNA-DIRECTED RNA POLYMERASE III SUBUNIT RPC7-LIKE; 1.
DR Pfam; PF11705; RNA_pol_3_Rpc31; 1.
DR PIRSF; PIRSF000777; RNA_polIII_C31; 2.
PE 3: Inferred from homology;
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PIRNR:PIRNR000777};
KW Reference proteome {ECO:0000313|Proteomes:UP000005447}.
FT REGION 128..218
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 128..158
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 159..197
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 204..218
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 218 AA; 25282 MW; C0BFC00A43DC1348 CRC64;
MASRGGGRGR GRGQLTFNME AVGIGKGDAL PPPTLQPSPL FPPLEFRPVP LPSGEEGEYV
LALKQELRGA MRQLPYFIRP AIPKKDVERY SDKYQLSGPI DSAIDWNPDW RRLPRELKIR
VRKLQKERTT ILPPKRPSKT TEDKEETMHK LETLEKKEEE VTSEEDEEKE EEEEKEEEEE
EDYDEEEHEE ETDYIMSYFD NGEDFGGDSD DNMDEAIY
//
