ID A0A286Y522_CAVPO Unreviewed; 181 AA.
AC A0A286Y522;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 24.
DE SubName: Full=Interferon stimulated exonuclease gene 20 {ECO:0000313|Ensembl:ENSCPOP00000032806.1};
GN Name=ISG20 {ECO:0000313|Ensembl:ENSCPOP00000032806.1};
OS Cavia porcellus (Guinea pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Caviidae;
OC Cavia.
OX NCBI_TaxID=10141 {ECO:0000313|Ensembl:ENSCPOP00000032806.1, ECO:0000313|Proteomes:UP000005447};
RN [1] {ECO:0000313|Proteomes:UP000005447}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=2N {ECO:0000313|Proteomes:UP000005447};
RX PubMed=21993624; DOI=10.1038/nature10530;
RA Lindblad-Toh K., Garber M., Zuk O., Lin M.F., Parker B.J., Washietl S.,
RA Kheradpour P., Ernst J., Jordan G., Mauceli E., Ward L.D., Lowe C.B.,
RA Holloway A.K., Clamp M., Gnerre S., Alfoldi J., Beal K., Chang J.,
RA Clawson H., Cuff J., Di Palma F., Fitzgerald S., Flicek P., Guttman M.,
RA Hubisz M.J., Jaffe D.B., Jungreis I., Kent W.J., Kostka D., Lara M.,
RA Martins A.L., Massingham T., Moltke I., Raney B.J., Rasmussen M.D.,
RA Robinson J., Stark A., Vilella A.J., Wen J., Xie X., Zody M.C., Baldwin J.,
RA Bloom T., Chin C.W., Heiman D., Nicol R., Nusbaum C., Young S.,
RA Wilkinson J., Worley K.C., Kovar C.L., Muzny D.M., Gibbs R.A., Cree A.,
RA Dihn H.H., Fowler G., Jhangiani S., Joshi V., Lee S., Lewis L.R.,
RA Nazareth L.V., Okwuonu G., Santibanez J., Warren W.C., Mardis E.R.,
RA Weinstock G.M., Wilson R.K., Delehaunty K., Dooling D., Fronik C.,
RA Fulton L., Fulton B., Graves T., Minx P., Sodergren E., Birney E.,
RA Margulies E.H., Herrero J., Green E.D., Haussler D., Siepel A., Goldman N.,
RA Pollard K.S., Pedersen J.S., Lander E.S., Kellis M.;
RT "A high-resolution map of human evolutionary constraint using 29 mammals.";
RL Nature 478:476-482(2011).
RN [2] {ECO:0000313|Ensembl:ENSCPOP00000032806.1}
RP IDENTIFICATION.
RC STRAIN=2N {ECO:0000313|Ensembl:ENSCPOP00000032806.1};
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR EMBL; AAKN02016044; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR RefSeq; XP_003475302.1; XM_003475254.2.
DR RefSeq; XP_013014437.1; XM_013158983.1.
DR RefSeq; XP_013014438.1; XM_013158984.1.
DR RefSeq; XP_013014439.1; XM_013158985.1.
DR Ensembl; ENSCPOT00000033449.1; ENSCPOP00000029409.1; ENSCPOG00000036489.1.
DR Ensembl; ENSCPOT00000043182.1; ENSCPOP00000032806.1; ENSCPOG00000036489.1.
DR GeneID; 100730384; -.
DR KEGG; cpoc:100730384; -.
DR CTD; 3669; -.
DR VEuPathDB; HostDB:ENSCPOG00000036489; -.
DR eggNOG; KOG2249; Eukaryota.
DR GeneTree; ENSGT00940000160781; -.
DR OrthoDB; 5479236at2759; -.
DR Proteomes; UP000005447; Unassembled WGS sequence.
DR Bgee; ENSCPOG00000036489; Expressed in uterine cervix and 6 other cell types or tissues.
DR GO; GO:0004527; F:exonuclease activity; IEA:UniProtKB-KW.
DR GO; GO:0003676; F:nucleic acid binding; IEA:InterPro.
DR Gene3D; 3.30.420.10; Ribonuclease H-like superfamily/Ribonuclease H; 1.
DR InterPro; IPR013520; Exonuclease_RNaseT/DNA_pol3.
DR InterPro; IPR047021; REXO1/3/4-like.
DR InterPro; IPR012337; RNaseH-like_sf.
DR InterPro; IPR036397; RNaseH_sf.
DR PANTHER; PTHR12801:SF59; INTERFERON-STIMULATED GENE 20 KDA PROTEIN; 1.
DR PANTHER; PTHR12801; RNA EXONUCLEASE REXO1 / RECO3 FAMILY MEMBER-RELATED; 1.
DR Pfam; PF00929; RNase_T; 1.
DR SMART; SM00479; EXOIII; 1.
DR SUPFAM; SSF53098; Ribonuclease H-like; 1.
PE 4: Predicted;
KW Exonuclease {ECO:0000256|ARBA:ARBA00022839};
KW Hydrolase {ECO:0000256|ARBA:ARBA00022839};
KW Nuclease {ECO:0000256|ARBA:ARBA00022839};
KW Reference proteome {ECO:0000313|Proteomes:UP000005447}.
FT DOMAIN 6..171
FT /note="Exonuclease"
FT /evidence="ECO:0000259|SMART:SM00479"
SQ SEQUENCE 181 AA; 20473 MW; 4D5E5891A7FE3482 CRC64;
MADSLEAVAM DCEMVGLGPL QESGLARCSL VSSTGSVLYD KFIRPEGVIT DYRTRVSGVT
RLHMETATPF AEARREILQL LKGKLVVGHD LKHDFKALKE DMSAYTIYDT STDWVLRREA
HLEHCKRVSL RVLCERLLHK RIQNNLFGHS SVEDAKATME LYLLSQRIQA RQGLPRLAES
D
//
