GenomeNet

Database: UniProt
Entry: A0A286Y8J7_DANRE
LinkDB: A0A286Y8J7_DANRE
Original site: A0A286Y8J7_DANRE 
ID   A0A286Y8J7_DANRE        Unreviewed;      2675 AA.
AC   A0A286Y8J7;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   10-FEB-2021, entry version 16.
DE   SubName: Full=Centromere protein F {ECO:0000313|Ensembl:ENSDARP00000143468};
GN   Name=cenpf {ECO:0000313|Ensembl:ENSDARP00000143468,
GN   ECO:0000313|ZFIN:ZDB-GENE-041111-205};
OS   Danio rerio (Zebrafish) (Brachydanio rerio).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes;
OC   Danionidae; Danioninae; Danio.
OX   NCBI_TaxID=7955 {ECO:0000313|Ensembl:ENSDARP00000143468, ECO:0000313|Proteomes:UP000000437};
RN   [1] {ECO:0000313|Ensembl:ENSDARP00000143468, ECO:0000313|Proteomes:UP000000437}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000143468,
RC   ECO:0000313|Proteomes:UP000000437};
RX   PubMed=23594743; DOI=10.1038/nature12111;
RA   Howe K., Clark M.D., Torroja C.F., Torrance J., Berthelot C., Muffato M.,
RA   Collins J.E., Humphray S., McLaren K., Matthews L., McLaren S., Sealy I.,
RA   Caccamo M., Churcher C., Scott C., Barrett J.C., Koch R., Rauch G.J.,
RA   White S., Chow W., Kilian B., Quintais L.T., Guerra-Assuncao J.A., Zhou Y.,
RA   Gu Y., Yen J., Vogel J.H., Eyre T., Redmond S., Banerjee R., Chi J., Fu B.,
RA   Langley E., Maguire S.F., Laird G.K., Lloyd D., Kenyon E., Donaldson S.,
RA   Sehra H., Almeida-King J., Loveland J., Trevanion S., Jones M., Quail M.,
RA   Willey D., Hunt A., Burton J., Sims S., McLay K., Plumb B., Davis J.,
RA   Clee C., Oliver K., Clark R., Riddle C., Elliot D., Threadgold G.,
RA   Harden G., Ware D., Begum S., Mortimore B., Kerry G., Heath P.,
RA   Phillimore B., Tracey A., Corby N., Dunn M., Johnson C., Wood J., Clark S.,
RA   Pelan S., Griffiths G., Smith M., Glithero R., Howden P., Barker N.,
RA   Lloyd C., Stevens C., Harley J., Holt K., Panagiotidis G., Lovell J.,
RA   Beasley H., Henderson C., Gordon D., Auger K., Wright D., Collins J.,
RA   Raisen C., Dyer L., Leung K., Robertson L., Ambridge K., Leongamornlert D.,
RA   McGuire S., Gilderthorp R., Griffiths C., Manthravadi D., Nichol S.,
RA   Barker G., Whitehead S., Kay M., Brown J., Murnane C., Gray E.,
RA   Humphries M., Sycamore N., Barker D., Saunders D., Wallis J., Babbage A.,
RA   Hammond S., Mashreghi-Mohammadi M., Barr L., Martin S., Wray P.,
RA   Ellington A., Matthews N., Ellwood M., Woodmansey R., Clark G., Cooper J.,
RA   Tromans A., Grafham D., Skuce C., Pandian R., Andrews R., Harrison E.,
RA   Kimberley A., Garnett J., Fosker N., Hall R., Garner P., Kelly D., Bird C.,
RA   Palmer S., Gehring I., Berger A., Dooley C.M., Ersan-Urun Z., Eser C.,
RA   Geiger H., Geisler M., Karotki L., Kirn A., Konantz J., Konantz M.,
RA   Oberlander M., Rudolph-Geiger S., Teucke M., Lanz C., Raddatz G.,
RA   Osoegawa K., Zhu B., Rapp A., Widaa S., Langford C., Yang F.,
RA   Schuster S.C., Carter N.P., Harrow J., Ning Z., Herrero J., Searle S.M.,
RA   Enright A., Geisler R., Plasterk R.H., Lee C., Westerfield M.,
RA   de Jong P.J., Zon L.I., Postlethwait J.H., Nusslein-Volhard C.,
RA   Hubbard T.J., Roest Crollius H., Rogers J., Stemple D.L.;
RT   "The zebrafish reference genome sequence and its relationship to the human
RT   genome.";
RL   Nature 496:498-503(2013).
RN   [2] {ECO:0000313|Ensembl:ENSDARP00000143468}
RP   IDENTIFICATION.
RC   STRAIN=Tuebingen {ECO:0000313|Ensembl:ENSDARP00000143468};
RG   Ensembl;
RL   Submitted (OCT-2017) to UniProtKB.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; BX936381; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR   Ensembl; ENSDART00000176858; ENSDARP00000143468; ENSDARG00000055133.
DR   ZFIN; ZDB-GENE-041111-205; cenpf.
DR   GeneTree; ENSGT00730000111187; -.
DR   OMA; YNAQLVQ; -.
DR   Proteomes; UP000000437; Chromosome 17.
DR   ExpressionAtlas; A0A286Y8J7; baseline.
DR   GO; GO:0000775; C:chromosome, centromeric region; IEA:InterPro.
DR   GO; GO:0070840; F:dynein complex binding; IEA:InterPro.
DR   GO; GO:0008017; F:microtubule binding; IEA:InterPro.
DR   GO; GO:0042803; F:protein homodimerization activity; IEA:InterPro.
DR   GO; GO:0008134; F:transcription factor binding; IEA:InterPro.
DR   GO; GO:0060271; P:cilium assembly; IMP:ZFIN.
DR   InterPro; IPR043513; Cenp-F.
DR   InterPro; IPR018302; CenpF/LEK1_Rb-prot-bd.
DR   InterPro; IPR019513; Centromere_CenpF_leu-rich_rpt.
DR   InterPro; IPR018463; Centromere_CenpF_N.
DR   PANTHER; PTHR18874; PTHR18874; 2.
DR   Pfam; PF10490; CENP-F_C_Rb_bdg; 1.
DR   Pfam; PF10473; CENP-F_leu_zip; 2.
DR   Pfam; PF10481; CENP-F_N; 1.
PE   1: Evidence at protein level;
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Proteomics identification {ECO:0000213|PeptideAtlas:A0A286Y8J7};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000437}.
FT   DOMAIN          1..295
FT                   /note="CENP-F_N"
FT                   /evidence="ECO:0000259|Pfam:PF10481"
FT   DOMAIN          1674..1814
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          1912..2050
FT                   /note="CENP-F_leu_zip"
FT                   /evidence="ECO:0000259|Pfam:PF10473"
FT   DOMAIN          2529..2573
FT                   /note="CENP-F_C_Rb_bdg"
FT                   /evidence="ECO:0000259|Pfam:PF10490"
FT   REGION          47..70
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          126..156
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          208..242
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          366..390
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          1433..1452
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2402..2540
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2582..2627
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          2642..2675
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          161..181
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          268..330
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          536..577
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          585..605
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          609..675
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          708..742
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          792..826
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          841..882
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          918..976
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1015..1070
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1082..1109
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1145..1214
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1236..1277
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1306..1392
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1499..1537
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1606..1656
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1678..1726
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1755..1845
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          1888..2027
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2070..2090
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2098..2129
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2137..2157
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2165..2199
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          2239..2266
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COMPBIAS        49..70
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        131..156
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        208..228
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        366..386
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2402..2418
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2419..2458
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2459..2474
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2526..2540
FT                   /note="Polyampholyte"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        2650..2675
FT                   /note="Polar"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   2675 AA;  307391 MW;  0EBDF2913C2ACBE8 CRC64;
     MSWAVEEWKD GLPAKALQKI QEIEAQLDKL KKERQQKQFQ MDSLEATLQK QKQKMDSEKS
     EASALKRENQ SLVESCEHLE KARQKLTHDI QTKEQQVNYL EGQLNSFKKQ TDRLEQEVKK
     YKHELERSQT SHASEIQQLS TPQKTFATPA TPNHWQQDSK ITDLQEKYNR EVEERKKLEA
     EIKVMHVKLL NQSSVSHKDI ARQQTGSSIF PWQQDQKSSH QSLPVMETPS RRRNGASGMP
     WSYDDTPIKP HQQFTSGAPS DTVGSQQMEQ LKNINQDLRS KVSELELRLQ AHEKDMKNQI
     NKFSEIQSQL EMAKKDVAEK DKLLNKSRDE LTKATGQYEQ SVSKCSAFEI KLKQVTEEMN
     CQRHNAESMH RSLEQKIKDQ ERESQKELAQ LQSSYQALDQ QFTQVKNKTS MEIQQAKKDH
     NVLQSEMDKV TALKNRLEKE LEELKQKLLR SEQALQASQV KEAETKKKFE EMQREKNTLN
     CQLDQGMKRV KQLEDEKQNT EQILAKNRMM VDDLKVKTQT QNEELTELRK KMDHQSVSSA
     QELENLKKTL IEAEAKNMKT QAELQKLVHD VELKENKICA VEKENEELKM TSNSCQKELA
     EMKKEYDALL QWKTEKEQLI NNAESNRNEL LAKVADLEKD KDNLSNAHGD LQKKMQDLEN
     EKIGLSGQID SLKGELLVKC VELEEKGRVY EELQQQFGET KIKHKKEMDN LNQQITLTQG
     KVSELEAKLL QETSKLEGME QAHGQLLAEY ESACILAMSK DSIIEMNKTE IVHLQESFTL
     RDQELEKFKV EKDILAKECE DRLAQNKELE QQKLNTETSL MEVLAKFTLL ESDLRCQKDL
     NAEIQGKYDE LSKIKEDLVE KVSSLEKREK DLINEVESLL QKNKSLCSLE EQFNCLVAEA
     EETRSSLEKV KELQVQTTTE LENQKTIAEN LAIDLEEEKK KALSIKQENT QLKVKQEEIE
     NKANDLFEKY ESLQKLHDAV CQENANHLKE ISIVTEALAE KDAMAERIAL IKTELETSNN
     LSATLKNSLE NLQTQFDSSV ELISSLEKKL HDMSDEKSLL EISIKELTER HNKESEVYVS
     ELETHIKKHK SLEEHISVLE TELQNKSLET KTASEKLEVT TQEMIKLKQD FSLSENKLSV
     VTDSNKKVAK ELEDMKQNVF LQEQEMEGLR LALSDLKNQE AAKSCEIETL KEKLQKAQSE
     HAKTSETLNE KNINMSKIKV QLEMLQMDLE DNENCINAFD AQVEELQGNV SILEAKLSES
     EAQRSNLESK LESVKEDYVK SSLEVSQLSA CLEESQKEQQ SRSVLVAELE SLRVIHEQLK
     VSLEQENCKQ ANLEAMYTNL MDQKLKLESE IQELKADTQG SQKQIDQLKQ ANDRLASQIA
     EQQIHIEQLQ SEKNLADTLN KEQTSGGNDQ DICEMPFANT SLLPFEEDTA ILGMSSPKGK
     HDSQEEPKTP LSAEEDYKDF ALQEQMQNKS SDIEDMSHVL KETVRTMEEQ TAIQIEQLKL
     QHATELQSME EQMLNIKNEL EAKLKEEKQH TEILSSQLEA TMQQLQELDI ASSSLLAADT
     SQNMGKFASG AQDDLIHHTE QSNSTLGIIT ESEHSNLETE TLKEVLRKRE EELLHLQSQF
     EVLESEMENE KLNKHIGELK EEIDSLTLQL QTSNCQLTDV MEMMESLEMA KGEWNEKFFQ
     IESELKRVRS EKANLEKHIL SMEADIEEMQ EQKQKQEAEL ETARRTNCSL EQQLNITMAE
     GGRLKEELIL CTDERESETH SLMKLKEKAD LLEKRETDTK ELIKELEDDI RVGKKQNEVA
     SDQISVLLKE KEQLIQQSQN LENKIVLLNE DNERLLSELN DIKHNDSFTS RETENMSSKI
     HSLEDENVRL SQSLEMSLLE KGEIASRLIS TQEEVAQMRQ GIEKLKVRIE SDERKKNHMS
     QLLKAAQRKA DVLQDNIEKL EREKELSEQN LEDAILQAET AKAELEEIQA ETQDLTKKIE
     EMTSELKDLK EEKYKLEQEL DQKNKLIEEL QLSIQEASVK LKSAEEATLN QEQMIKDFQF
     KVGAMEEELR LFQTEVESKE VKALELASHL LSLESENKEF AQRVLEYERS QEELHSSNQS
     LLKDFESKQQ ELSEENTQLR SQIAELQALS LIREEQDEEL QKDKVELQST IAQLEEKTQM
     QSTKMEVMQN SISSLEINIQ QLEGQLDAMK LMNVELTGKL NSLQESSLHL ETQHKQELCE
     AKEIQNALEI NQNLLTCQLQ ESQKQIEEYK FSLEALAAEK DGLQKSISVI QESHDVQLKE
     NNMRHEENLK RTQQQLEVEL NALKENILVA EKNAAQYQSD LESIKSQNAE KDSALKELQN
     KWENCQKEKA ELDSKITRLS KEKDSAMSKI NLWMKSCKQL ENEKQTLQEE LQQQGQEIET
     LKASKEQAEG SSSSGALQEE LEELKEALEE KSREADDSMD RYCSLMVKVH KLEDSNESLK
     NQLKQLSTQT KTPKSRRSLR SETSDLENSN PEGVTSGKRQ RAIDDTPNKA QEALHNITKR
     LKAAAATPKA KQDDEDFRPE GLPELVQKGF ADIPVGEMSP FIVRRTTAQR CSPRLAARTT
     AVLQSSGSAE HPAQISMQTA EGRTPNTVQK PKATPSRNVP LLSTLTNSPL KNSCERLAPV
     IEQKISRRSR SFKNSPQTSE QVTASPKQND NCQVQ
//
DBGET integrated database retrieval system