ID A0A286ZKM9_PIG Unreviewed; 1246 AA.
AC A0A286ZKM9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=Protein phosphatase 1 regulatory subunit 9A {ECO:0000313|Ensembl:ENSSSCP00000032024.2};
GN Name=PPP1R9A {ECO:0000313|Ensembl:ENSSSCP00000032024.2,
GN ECO:0000313|VGNC:VGNC:91743};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000032024.2, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000032024.2, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000032024.2,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000032024.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
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DR AlphaFoldDB; A0A286ZKM9; -.
DR Ensembl; ENSSSCT00000053487.3; ENSSSCP00000032024.2; ENSSSCG00000015329.5.
DR VGNC; VGNC:91743; PPP1R9A.
DR GeneTree; ENSGT00940000155538; -.
DR Proteomes; UP000008227; Chromosome 9.
DR Bgee; ENSSSCG00000015329; Expressed in amygdala and 40 other cell types or tissues.
DR ExpressionAtlas; A0A286ZKM9; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR GO; GO:0007399; P:nervous system development; IEA:UniProtKB-KW.
DR CDD; cd00992; PDZ_signaling; 1.
DR Gene3D; 2.30.42.10; -; 1.
DR InterPro; IPR040645; Neurabin-1/2_PDZ.
DR InterPro; IPR043446; Neurabin-like.
DR InterPro; IPR001478; PDZ.
DR InterPro; IPR036034; PDZ_sf.
DR PANTHER; PTHR16154; NEURABIN; 1.
DR PANTHER; PTHR16154:SF22; NEURABIN-1; 1.
DR Pfam; PF00595; PDZ; 1.
DR Pfam; PF17817; PDZ_5; 1.
DR SMART; SM00228; PDZ; 1.
DR SUPFAM; SSF50156; PDZ domain-like; 1.
DR PROSITE; PS50106; PDZ; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Cytoplasm {ECO:0000256|ARBA:ARBA00022490};
KW Cytoskeleton {ECO:0000256|ARBA:ARBA00023212};
KW Neurogenesis {ECO:0000256|ARBA:ARBA00022902};
KW Phosphoprotein {ECO:0000256|ARBA:ARBA00022553};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A286ZKM9};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 504..592
FT /note="PDZ"
FT /evidence="ECO:0000259|PROSITE:PS50106"
FT REGION 1..66
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 85..112
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 147..224
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 249..349
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 627..646
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 888..924
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 937..959
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 976..1007
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1051..1072
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1112..1170
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1202..1246
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 600..627
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 680..777
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 1..28
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 31..53
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..170
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 178..224
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 280..295
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 297..329
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 628..645
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 938..958
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1056..1072
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1112..1157
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1202..1238
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1246 AA; 139103 MW; 5729B939CC2AFE7D CRC64;
MLKTESSGER TTLRSASPHR NAYRTEFQAL KSTFDKPKSD GEQKAKEGEG SQQSRGRKYG
SNVNRIKNLF MQMGMEPSEN AAVIAKTRGK GGPSSPQRRM KPKEFLEKTD GSVVKLESSV
SERISRFDTM YDGPSYSKFT ETRKMFERSV HESGQNNRYS PKKEKAGGGE PPEEWGGSKS
NRGSTDSLDS LSSRTEAVSP TVSQLSAVFE NTDSPGAIIS EKTENNEYSV TGHYPLNLPS
VTVTNLDTFG HLKDSNSWSP PSKHSDDAED AEKSNVIPVL EVASKSTSLA SVPSEEAEQN
KEAEDSTSNQ ESSDRIDRDF PEEPCAENKA VPESEIPSPQ NEPSEDAEAN LVGSEAAMQQ
KKDLAGGDFT SAVVSRFACG KELLEDSHHF GSSHVYMHSD YNVYRVRSRY NSDWGETGTE
QDEQEDSDEN SYYQPDLEYS EIVGLPEEED IPANRKIKFS SAPIKVFSTY SNEDYDRRND
EVDPVAASAE YELEKRVEKL ELFPVELEKD EDGLGISIIG MGVGADAGLE KLGIFVKTVT
EGGAAQRDGR IQVNDQIVEV DGISLVGVTQ NFAATVLRNT KGNVRFVIGR EKPGQVSEVA
QLISQTLEQE RRQRELLEQH YAQYDADDDE TGEYATDEEE DEVGPVLPGS DLAIEVFELP
ENEDMFSPSD LDTTKLSHKF KELQIKHAVT EAEIQKLKTK LQAAENEKVR WELEKTQLQQ
NIEENKERML KLESYWIEAQ TLCHTVNEHL KETQSQYQAL EKKYNKAKKL IKDFQQKELD
FIKRQEAERK KIEDLEKAHL VEVQGLQVRI RDLEAEVFRL LKQNGTQVNN NNNIFERRTS
LGEVSKGDSI ENLDVKQTSC HDGLSQDFNE AVPETERLDS KALKTRAQLS VKNRRQRPSR
TRLYDSVSST DGEDSLERKP SNSFYNHMHI TKSLLPKGLR TSPESDSGAP SLTPVAGSVP
FSSDHIAELQ EGPLHLEREP SSSPGGGTSL SSPSKSEHDN EESLCHHQAT TKKILQEKDG
ATGPRSLRAS SSLVVRGGKI KRKFVDLGAP LRRSSNKGKK WKEKEKEANR FSPGGRIFRS
RLEPWKPKPA SMCSTGLPFS WFNESRKGSY SFRNLPSPKS PLQPSPETLI SDKKGSKNFT
FTDDFSPSST SSADLSGLGA EPKTPGLSQS LALSSDEALG MTSSQDRAVV KKKLKEMKVS
LEKARKAQEK MEKQREKLRR KEQEQMQRKS KKTERMAAAT EGAGEQ
//
