ID   A0A286ZLL4_PIG          Unreviewed;       432 AA.
AC   A0A286ZLL4;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   11-DEC-2019, sequence version 2.
DT   27-MAR-2024, entry version 33.
DE   SubName: Full=ETS transcription factor ELK4 {ECO:0000313|Ensembl:ENSSSCP00000032355.2};
GN   Name=ELK4 {ECO:0000313|Ensembl:ENSSSCP00000032355.2,
GN   ECO:0000313|VGNC:VGNC:87647};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000032355.2, ECO:0000313|Proteomes:UP000008227};
RN   [1] {ECO:0000313|Ensembl:ENSSSCP00000032355.2, ECO:0000313|Proteomes:UP000008227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000032355.2,
RC   ECO:0000313|Proteomes:UP000008227};
RG   Porcine genome sequencing project;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSSCP00000032355.2}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|RuleBase:RU004019}.
CC   -!- SIMILARITY: Belongs to the ETS family. {ECO:0000256|ARBA:ARBA00005562,
CC       ECO:0000256|RuleBase:RU004019}.
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DR   RefSeq; XP_003357444.1; XM_003357396.3.
DR   RefSeq; XP_005667593.1; XM_005667536.2.
DR   AlphaFoldDB; A0A286ZLL4; -.
DR   Ensembl; ENSSSCT00000037380.3; ENSSSCP00000032355.2; ENSSSCG00000025182.4.
DR   GeneID; 100626141; -.
DR   KEGG; ssc:100626141; -.
DR   CTD; 2005; -.
DR   VGNC; VGNC:87647; ELK4.
DR   eggNOG; KOG3806; Eukaryota.
DR   GeneTree; ENSGT00940000158900; -.
DR   OrthoDB; 4237692at2759; -.
DR   Proteomes; UP000008227; Chromosome 9.
DR   Bgee; ENSSSCG00000025182; Expressed in tonsil and 42 other cell types or tissues.
DR   ExpressionAtlas; A0A286ZLL4; baseline and differential.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IEA:InterPro.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR   Gene3D; 1.10.10.10; Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain; 1.
DR   InterPro; IPR000418; Ets_dom.
DR   InterPro; IPR046328; ETS_fam.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   PANTHER; PTHR11849; ETS; 1.
DR   PANTHER; PTHR11849:SF21; ETS DOMAIN-CONTAINING PROTEIN ELK-4; 1.
DR   Pfam; PF00178; Ets; 1.
DR   PRINTS; PR00454; ETSDOMAIN.
DR   SMART; SM00413; ETS; 1.
DR   SUPFAM; SSF46785; Winged helix' DNA-binding domain; 1.
DR   PROSITE; PS00345; ETS_DOMAIN_1; 1.
DR   PROSITE; PS00346; ETS_DOMAIN_2; 1.
DR   PROSITE; PS50061; ETS_DOMAIN_3; 1.
PE   3: Inferred from homology;
KW   DNA-binding {ECO:0000256|ARBA:ARBA00023125, ECO:0000256|RuleBase:RU004019};
KW   Nucleus {ECO:0000256|RuleBase:RU004019};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT   DOMAIN          5..85
FT                   /note="ETS"
FT                   /evidence="ECO:0000259|PROSITE:PS50061"
FT   REGION          116..139
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          175..327
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          412..432
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        209..264
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        274..295
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        304..320
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   432 AA;  46510 MW;  27B8381920285086 CRC64;
     MDSAITLWQF LLQLLKEPQN DHMICWTSNN GEFKLLQAEE VARLWGIRKN KPNMNYDKLS
     RALRYYYVKN IIKKVNGQKF VYKFVSYPEI LSMDPMTVGR VEGDCEALGI AELSSNSSRD
     VENGGKEKPL QPGAKTSSRN DYIHSGLYSS FTLNSLNSSS RKLFKSIKVE NPAEKLAEKK
     SPQEPTPSVI KFVTTPSKKP PVEPFAATIS TGPSISPSSE ETIQALETLA SPKLSSLEAP
     TSASSVTAAF TTAPPSLSGS PLQEAPGTPS PPLSSNPDMD TDMESVASQP VELSENLSLE
     PKDQDSALPE KDKTNNSSRS KKPKGLELAP TLVITGSDPS PLGILSPSLP TASLTPALFS
     QTPILLTPSP LLSSIHFWST LSPVAPLSPA RLQGANTLFQ FPSVLNSHGP FTLSGLDGPS
     TPGPFSPDLQ KT
//