ID A0A286ZR56_PIG Unreviewed; 1362 AA.
AC A0A286ZR56;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 3.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=YEATS domain containing 2 {ECO:0000313|Ensembl:ENSSSCP00000034109.3};
GN Name=YEATS2 {ECO:0000313|Ensembl:ENSSSCP00000034109.3,
GN ECO:0000313|VGNC:VGNC:95023};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000034109.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000034109.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000034109.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000034109.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|PROSITE-ProRule:PRU00376}.
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DR STRING; 9823.ENSSSCP00000034109; -.
DR Ensembl; ENSSSCT00000050821.3; ENSSSCP00000034109.3; ENSSSCG00000011776.5.
DR VGNC; VGNC:95023; YEATS2.
DR eggNOG; KOG3149; Eukaryota.
DR GeneTree; ENSGT00940000156789; -.
DR InParanoid; A0A286ZR56; -.
DR Reactome; R-SSC-9772755; Formation of WDR5-containing histone-modifying complexes.
DR Proteomes; UP000008227; Chromosome 13.
DR Bgee; ENSSSCG00000011776; Expressed in forelimb bud and 43 other cell types or tissues.
DR ExpressionAtlas; A0A286ZR56; baseline and differential.
DR GO; GO:0140672; C:ATAC complex; IBA:GO_Central.
DR GO; GO:0072686; C:mitotic spindle; IEA:Ensembl.
DR GO; GO:0035267; C:NuA4 histone acetyltransferase complex; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0042393; F:histone binding; IBA:GO_Central.
DR GO; GO:0140566; F:histone reader activity; IEA:Ensembl.
DR GO; GO:0140030; F:modification-dependent protein binding; IEA:Ensembl.
DR GO; GO:0017025; F:TBP-class protein binding; IEA:Ensembl.
DR GO; GO:0003714; F:transcription corepressor activity; IEA:Ensembl.
DR GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR GO; GO:0000122; P:negative regulation of transcription by RNA polymerase II; IEA:Ensembl.
DR GO; GO:0051726; P:regulation of cell cycle; IEA:Ensembl.
DR GO; GO:0051302; P:regulation of cell division; IEA:Ensembl.
DR GO; GO:0045995; P:regulation of embryonic development; IEA:Ensembl.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR GO; GO:0090043; P:regulation of tubulin deacetylation; IEA:Ensembl.
DR CDD; cd16907; YEATS_YEATS2_like; 1.
DR Gene3D; 2.60.40.1970; YEATS domain; 1.
DR InterPro; IPR038704; YEAST_sf.
DR InterPro; IPR005033; YEATS.
DR PANTHER; PTHR23195; YEATS DOMAIN; 1.
DR PANTHER; PTHR23195:SF7; YEATS DOMAIN-CONTAINING PROTEIN 2; 1.
DR Pfam; PF03366; YEATS; 1.
DR PROSITE; PS51037; YEATS; 1.
PE 4: Predicted;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242, ECO:0000256|PROSITE-
KW ProRule:PRU00376}; Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT REGION 117..197
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 367..391
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 515..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 810..842
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 47..74
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 117..152
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 153..169
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 170..192
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1362 AA; 144410 MW; 7ADC21A350943CFB CRC64;
MSGIKRTVKE TDPDYEDVSV ALPNKRHKAI ENSARDAAVQ KIETIIKEQF ALEMKNKEHE
IEVIDQRLIE ARRMMDKLRA CIVANYYASA GLLKVSEGSK TCDTMVFNHP AIKKFLESPS
RSSSPANQRS ETPSANHSES DSLSQHNDFL SDKDTNSNMD VEERLSNNTE QRPSRNTGRD
TSSITGSHKT EQRNADLAVD ETSRLFVKKT IVVGNVSKYI PPDKREENDQ STHKWMVYVR
GSRREPSINH FVKKVWFFLH PSYKPNDLVE VREPPFHLTR RGWGEFPVRV QVHFKDSQNK
RIDIIHNLKL DRTYTGLQTL GAETVVDVEL HRHSLGEDSA YPRSSESDIS DAPPSLPLTI
PAPVKASSPI KPSHDPVPDS SVEKGFPAST EAERHTTFYS LPSSVERTPT KMTTSQKVTF
CSHGNSAFQP IASSCKIVPQ SQVPNPESPG KSFQPITMSC KIVSGSPIST PSPSPLPRTP
TSTPVHVKQG TTSSVINNPY VIVDKPGQVI GATTPTAGSP TSKLSTASQA SQGTGSPIPK
IHGSSFVTST VKQEDSLFAS MPPLCPIGSH PKVQSPKPIT GGLGAFTKVI IKQEPGEASH
IPTTGAASQS PLPQYVTVKG GHMIAVSPQK QVLTAGEGTA QSPKIQPSKV VGVPVGSTLP
STVKQAVAIS GGQILVAKAS SSVTKAVGPK QVVTQGVAKA IVSGGGGTIV AQPVQALTKA
QVTAAGPQKS GSQGSVMATL QLPATNLANL ANLPPGTKLY LTTNSKNPSG KGKLLLIPQG
AILRATNNAN LQSGSAGGGG GGGGGGGGGG GGGGSGGGSS GGGGGGGGTG GGGTAAQSPA
GPGGISQHLT YTSYILKQTP QGTFLVGQPS PQTSGKQLTT GSVVQGTLGV STSSAQGQQT
LKVISGQKTT LFTQAAPGGQ ASLMKISDST LKSVPATSQL SKPGTTMLRV AGGVITTATS
PAVALSANGP AQQLLKIHSS QSNPQQAVLT IPSQLKPLSV NTSGGVQTIL MPVNKVVQSF
SASKSPAIVP AATPAPVVPS SAPATVTKVK TEPETPGPSC LSQDGQTAVK TEESSELGSY
VIKIDHLETV QQLLTAIVKK IPLITAKSED ASCFSAKSVE QYYGWNIGKR RAAEWQRAMT
MRKVLQEILE KNPRFHHLTP LKTKHIAHWC RCHGYTPPDP ESLRSEGDSI EDVLTQIDSE
PECPSSFSSA DNLCRKLEDL QQFQKSEPEN EEEVDILSLS EPLKINIKKE QEEKQEEMKF
YLPPTPGSEF IGDITQKIGI TLQPVALHRN VYASVVEDMI LKATEQLVSD ILRQALAVGY
QAASHNRIPK EITVSNIHQA ICNIPFLDFL TNKHMGILNE DQ
//
