ID A0A286ZX85_PIG Unreviewed; 321 AA.
AC A0A286ZX85;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=Zinc finger protein 705A {ECO:0000313|EMBL:HDA24252.1, ECO:0000313|EMBL:HDA77973.1};
GN Name=LOC100525433 {ECO:0000313|Ensembl:ENSSSCP00000036292.1};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000036292.1, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000036292.1, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000036292.1,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:HDA24252.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30723633; DOI=.7717/peerj.6374;
RA Gilbert D.G.;
RT "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL PeerJ 7:E6374-E6374(2019).
RN [3] {ECO:0000313|Ensembl:ENSSSCP00000036292.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the krueppel C2H2-type zinc-finger protein
CC family. {ECO:0000256|ARBA:ARBA00006991}.
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DR EMBL; DQIR01068776; HDA24252.1; -; Transcribed_RNA.
DR EMBL; DQIR01071229; HDA26705.1; -; Transcribed_RNA.
DR EMBL; DQIR01122497; HDA77973.1; -; Transcribed_RNA.
DR EMBL; DQIR01129335; HDA84811.1; -; Transcribed_RNA.
DR EMBL; DQIR01193487; HDB48964.1; -; Transcribed_RNA.
DR RefSeq; XP_005671717.1; XM_005671660.2.
DR RefSeq; XP_013839447.1; XM_013983993.1.
DR RefSeq; XP_013839448.1; XM_013983994.1.
DR RefSeq; XP_013839449.1; XM_013983995.1.
DR RefSeq; XP_013839450.1; XM_013983996.1.
DR RefSeq; XP_013842511.1; XM_013987057.1.
DR RefSeq; XP_013842512.1; XM_013987058.1.
DR RefSeq; XP_013842513.1; XM_013987059.1.
DR RefSeq; XP_013842514.1; XM_013987060.1.
DR PaxDb; 9823-ENSSSCP00000023945; -.
DR Ensembl; ENSSSCT00000054332.3; ENSSSCP00000036292.1; ENSSSCG00000036877.3.
DR GeneID; 100525433; -.
DR KEGG; ssc:100525433; -.
DR eggNOG; KOG1721; Eukaryota.
DR GeneTree; ENSGT00940000163552; -.
DR OMA; GEDFTHS; -.
DR OrthoDB; 3079685at2759; -.
DR Proteomes; UP000008227; Chromosome 15.
DR Bgee; ENSSSCG00000036877; Expressed in epididymis and 44 other cell types or tissues.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR CDD; cd07765; KRAB_A-box; 1.
DR Gene3D; 6.10.140.140; -; 1.
DR Gene3D; 3.30.160.60; Classic Zinc Finger; 6.
DR InterPro; IPR001909; KRAB.
DR InterPro; IPR036051; KRAB_dom_sf.
DR InterPro; IPR036236; Znf_C2H2_sf.
DR InterPro; IPR013087; Znf_C2H2_type.
DR PANTHER; PTHR23232; KRAB DOMAIN C2H2 ZINC FINGER; 1.
DR PANTHER; PTHR23232:SF146; KRAB DOMAIN-CONTAINING PROTEIN; 1.
DR Pfam; PF01352; KRAB; 1.
DR Pfam; PF00096; zf-C2H2; 3.
DR Pfam; PF13465; zf-H2C2_2; 1.
DR SMART; SM00349; KRAB; 1.
DR SMART; SM00355; ZnF_C2H2; 7.
DR SUPFAM; SSF57667; beta-beta-alpha zinc fingers; 4.
DR SUPFAM; SSF109640; KRAB domain (Kruppel-associated box); 1.
DR PROSITE; PS50805; KRAB; 1.
DR PROSITE; PS00028; ZINC_FINGER_C2H2_1; 6.
DR PROSITE; PS50157; ZINC_FINGER_C2H2_2; 7.
PE 3: Inferred from homology;
KW DNA-binding {ECO:0000256|ARBA:ARBA00023125};
KW Metal-binding {ECO:0000256|ARBA:ARBA00022723};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Transcription {ECO:0000256|ARBA:ARBA00023163};
KW Transcription regulation {ECO:0000256|ARBA:ARBA00023015};
KW Zinc {ECO:0000256|ARBA:ARBA00022833};
KW Zinc-finger {ECO:0000256|ARBA:ARBA00022771, ECO:0000256|PROSITE-
KW ProRule:PRU00042}.
FT DOMAIN 7..78
FT /note="KRAB"
FT /evidence="ECO:0000259|PROSITE:PS50805"
FT DOMAIN 115..142
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 141..170
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 171..198
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 199..226
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 227..254
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 255..282
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
FT DOMAIN 283..310
FT /note="C2H2-type"
FT /evidence="ECO:0000259|PROSITE:PS50157"
SQ SEQUENCE 321 AA; 36852 MW; B02E5F72229941B7 CRC64;
MQPLESVTFE DVAIDFSQEE WALLDTSQRK LFRDVMLENI NHLVSLGYHH SKSDVIFHLE
QGEELWFEGR GFFQSHSPGR ESALKEEMLA TWNISSKDTS TIIPVQVSHT PEDPFECNDL
GEDFIYSSTL SQHLLTHMEK IPCISKQCQK PLSDQSYLNQ HKQIHTRGKS CECHLCGKAF
SNCSSLRRHE MTHTGEKPYE CHICGNAFIQ SSDLRKHNLT HTGEKPYECH LCGKAFSQSS
NLRQHERTHT GEQPYECQLC GKAFSKCSAL RRHERTHTGE KPYECHLCGK SFSQCSALRR
HEGTHNGEKS MNAFSKYSDL R
//
