ID A0A286ZYY8_PIG Unreviewed; 1594 AA.
AC A0A286ZYY8;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 36.
DE SubName: Full=MYB binding protein 1a {ECO:0000313|Ensembl:ENSSSCP00000036923.2};
GN Name=MYBBP1A {ECO:0000313|Ensembl:ENSSSCP00000036923.2,
GN ECO:0000313|VGNC:VGNC:90497};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000036923.2, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000036923.2, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000036923.2,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000036923.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the MYBBP1A family.
CC {ECO:0000256|ARBA:ARBA00006809}.
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DR SMR; A0A286ZYY8; -.
DR STRING; 9823.ENSSSCP00000036923; -.
DR Ensembl; ENSSSCT00000050473.2; ENSSSCP00000036923.2; ENSSSCG00000017882.5.
DR VGNC; VGNC:90497; MYBBP1A.
DR eggNOG; KOG1926; Eukaryota.
DR GeneTree; ENSGT00390000017457; -.
DR InParanoid; A0A286ZYY8; -.
DR Reactome; R-SSC-5250924; B-WICH complex positively regulates rRNA expression.
DR Proteomes; UP000008227; Chromosome 12.
DR Bgee; ENSSSCG00000017882; Expressed in psoas major muscle and 44 other cell types or tissues.
DR ExpressionAtlas; A0A286ZYY8; baseline and differential.
DR GO; GO:0110016; C:B-WICH complex; IEA:Ensembl.
DR GO; GO:0005737; C:cytoplasm; IEA:Ensembl.
DR GO; GO:0042564; C:NLS-dependent protein nuclear import complex; IEA:Ensembl.
DR GO; GO:0005730; C:nucleolus; IBA:GO_Central.
DR GO; GO:0070888; F:E-box binding; IEA:Ensembl.
DR GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR GO; GO:0003714; F:transcription corepressor activity; IBA:GO_Central.
DR GO; GO:0042149; P:cellular response to glucose starvation; IEA:Ensembl.
DR GO; GO:0032922; P:circadian regulation of gene expression; IEA:Ensembl.
DR GO; GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Ensembl.
DR GO; GO:2000210; P:positive regulation of anoikis; IEA:Ensembl.
DR GO; GO:0045945; P:positive regulation of transcription by RNA polymerase III; IEA:Ensembl.
DR GO; GO:1903450; P:regulation of G1 to G0 transition; IEA:Ensembl.
DR GO; GO:0022904; P:respiratory electron transport chain; IEA:Ensembl.
DR InterPro; IPR016024; ARM-type_fold.
DR InterPro; IPR007015; DNA_pol_V/MYBBP1A.
DR PANTHER; PTHR13213:SF2; MYB-BINDING PROTEIN 1A; 1.
DR PANTHER; PTHR13213; MYB-BINDING PROTEIN 1A FAMILY MEMBER; 1.
DR Pfam; PF04931; DNA_pol_phi; 1.
DR PRINTS; PR01217; PRICHEXTENSN.
DR SUPFAM; SSF48371; ARM repeat; 1.
PE 1: Evidence at protein level;
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A286ZYY8};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 703..759
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 982..1048
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1250..1594
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 715..743
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 744..758
FT /note="Acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1376..1394
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1403..1425
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1436..1454
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1468..1499
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1508..1528
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 1594 AA; 176979 MW; D79072A22DD1C462 CRC64;
MAETESMDVA EPVSPVEVPK TGAGPADRHG LLKHSREFLD FFWDIAKPQQ ETRLEATEKL
LEYLRARPKG SSEMKYALKR LITGLGVGRE TARPCYSLAL AQLLQSFEDI PLCSILQQIQ
EKYNLQKVKK GMMRPALFAN LFGVLALFQS GRLVKDSEVL MKSVKLLQVL AQHYNHLQEQ
PQKALVDILS EVPEAVLQEV LPKVLKTELS SVLGSPEHLE LFLLAQQKVP KKLEKLMGPV
NLFSDENIPR LVTVLKMAAT SVKKERKLPA VALDLLRLAL QEDKFPWFWK EVVEQGLLKK
QFWPASYLCF RLLGAALPLL SKEQLQLVMR GDLIRHYGEH MVTAKLPNHY KFAPEMNQYV
EAFLEGCRDD AERQLAMVVA FTSVTNQGLP VMPTFWRVVK LLSPPALQGY VAWLRDMFLQ
PDLDALVDFS TNNQKKTQDA SLHGPERAVF RLRKWIILRL VSIVDCVHAE KEEALTEEVA
RFCFFHSFFE TKKPTSQIPE TEQHFSPALE SRTREVVSGA FFSLLQTLST QFRQAPEQAQ
DRQPWTYRLV QFADMLLSHS RNVVPLTPFT TQQRQAWDRM LKTLKELETH SSEAKAKATA
FQHLLLLVGI HLFKSPAESC DLLGDIQTCI KKSLGEKTRR TRSKATNPQE LPWVEVLVEI
LLSLLAQPSH LMRQVARSVF SHICSHLTPR ALQLILDVLN PEESQDEDDN VVVTDDSKEE
PLGEAEDKSS DDEDNKGDKN SESEEESDGE ESDEAERDGD VDQGFREQLM AVLQAGKALV
SGSGPGPSVC LGLSLPACDQ AAHGASVPKG GGDGEDDDDE ELGDEAMMAL DENLASLFAE
QKLRIQARRE EKNKLQKEKA LRRDFQIRVL DLIEVLVTKQ PENPLVLELL EPLLHIIRRS
MRTSSAKQEQ DLLHKTARIF THHLCRSRHY CRDVGDRVET VYAQLERLVR QAGQQADSSV
ALYHFNASLY LLRVLKGSTV DKSAQKEKTT AADASAQGRE VSRPDPGRLP CPEMGARPRG
RGATRPFHGV GVEAKPSPGS SGPPSEGSPA SHCALSLVVQ AATCLDLSRV TPIYSAVLSS
FLTKRNSPLT VPMFLSLFCR HPMLCKNLLP LVVEHIASHS RPRHQAQACL LLQKSLHTRE
LRLCFKAPEW EQLMGQILAK VSENLRTLGE AETKSEHQKE LSSLELLNTL FKNIRQEKLT
TDLSAVLGVL QSQQPRLQQK LQQEEHSTGT GSSRLHDLYW QAMKLLGVQR PKSEKDAKEV
PEATQNPVSM KRKKKGFLPE TKKRKKRKSE GAVQGEGAAP AATGGDQPPS TGKKRRNKRK
AKVPAPSQVN GMPAAKSPAP DSPAQPPKPK KRKRKQSQVN GTPATKSPAP DSPAQTPKPQ
KQNEKQSQVN ATPAIESPAP DLSAQTPKPQ KKNPKLSQVN GTPATRSPAP DPPTQTPKLQ
KKNQKLSQAN AMPATKSPAP GPPAASPTAS AQTPKLQKKN QKLSQVTVTP ATKSPVSDLP
TISPGPPAQT PKLQKKNQKL SQMKGATPES LDSPEEPAAK KRPKKNLPQK GILGKSPQSA
LPRKKARLSL ASRSPSLLQS GARKKVQPRK VKKL
//
