ID A0A287A2G9_PIG Unreviewed; 525 AA.
AC A0A287A2G9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=Keratin 71 {ECO:0000313|Ensembl:ENSSSCP00000038135.1};
GN Name=KRT71 {ECO:0000313|Ensembl:ENSSSCP00000038135.1,
GN ECO:0000313|VGNC:VGNC:107238};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000038135.1, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000038135.1, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000038135.1,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000038135.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR RefSeq; XP_013840685.1; XM_013985231.1.
DR AlphaFoldDB; A0A287A2G9; -.
DR SMR; A0A287A2G9; -.
DR STRING; 9823.ENSSSCP00000038135; -.
DR PaxDb; 9823-ENSSSCP00000000264; -.
DR Ensembl; ENSSSCT00000057314.1; ENSSSCP00000038135.1; ENSSSCG00000000247.5.
DR GeneID; 106506651; -.
DR KEGG; ssc:106506651; -.
DR CTD; 112802; -.
DR VGNC; VGNC:107238; KRT71.
DR GeneTree; ENSGT00940000162089; -.
DR InParanoid; A0A287A2G9; -.
DR OrthoDB; 4640531at2759; -.
DR Reactome; R-SSC-6805567; Keratinization.
DR Reactome; R-SSC-6809371; Formation of the cornified envelope.
DR Proteomes; UP000008227; Chromosome 5.
DR Bgee; ENSSSCG00000000247; Expressed in integumental system and 1 other cell type or tissue.
DR GO; GO:0045095; C:keratin filament; IBA:GO_Central.
DR GO; GO:0030280; F:structural constituent of skin epidermis; IBA:GO_Central.
DR GO; GO:0031069; P:hair follicle morphogenesis; IEA:Ensembl.
DR GO; GO:0045109; P:intermediate filament organization; IBA:GO_Central.
DR GO; GO:0031424; P:keratinization; IBA:GO_Central.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF16; KERATIN, TYPE II CYTOSKELETAL 71; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 2.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 3.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A287A2G9};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 132..445
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT REGION 493..525
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 187..263
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 343..423
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 525 AA; 57476 MW; 65313E72407EC4B3 CRC64;
MSRQFTCKSG AASKGGFSGC SAVLSGGSSS SYRAGGKGLS GGFGSRSLYN LGGIRSISFN
MANSTGKSGG YGFGRGRASG FAGSMFGSVA LGPVCPTVCP PGGIHQVTVN ESLLAPLNVE
LDPEIQKVRA QEREQIKALN NKFASFIDKV RFLEQQNQVL ETKWELLQQL DLNNCKNNLE
PILEGYISTL RKQLEALSGD RVRLDSELRS VRDVVEDYKK RYEEEINRRT AAENEFVLLK
KDVDAAYANK VELQAKVDSM DQEIKFFKCL YEAEIAQIQS HISDMSVILS MDNNRDLNLD
SIIDEVRAQY EEIALKSKAE AEALYQTKFQ ELQLAAGRHG DDLKNTKNEI SELTRLIQRI
RSEIENVKKQ ASNLETAIAD AEQRGDNALK DARAKLDELE GALHQAKEEL ARMLREYQEL
MSLKLALDME IATYRKLLES EECRMSGEFP SPVSISIIST TSGSSGYGFR PSSVSGGYVA
NSGSCISGVC SVRGGETRSR SSTTDYKDAL GKGSSLSAPS KKASR
//
