ID A0A287A3X5_PIG Unreviewed; 682 AA.
AC A0A287A3X5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 3.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Solute carrier family 26 member 10 {ECO:0000313|Ensembl:ENSSSCP00000038590.3};
GN Name=SLC26A10 {ECO:0000313|Ensembl:ENSSSCP00000038590.3,
GN ECO:0000313|VGNC:VGNC:93025};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000038590.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000038590.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000038590.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000038590.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU362052}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU362052}.
CC -!- SIMILARITY: Belongs to the SLC26A/SulP transporter (TC 2.A.53) family.
CC {ECO:0000256|RuleBase:RU362052}.
CC -!- CAUTION: Lacks conserved residue(s) required for the propagation of
CC feature annotation. {ECO:0000256|RuleBase:RU362052}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR AlphaFoldDB; A0A287A3X5; -.
DR STRING; 9823.ENSSSCP00000038590; -.
DR Ensembl; ENSSSCT00000061017.3; ENSSSCP00000038590.3; ENSSSCG00000036029.3.
DR VGNC; VGNC:93025; SLC26A10.
DR GeneTree; ENSGT01070000253775; -.
DR InParanoid; A0A287A3X5; -.
DR Proteomes; UP000008227; Chromosome 5.
DR Bgee; ENSSSCG00000036029; Expressed in longissimus lumborum muscle and 25 other cell types or tissues.
DR GO; GO:0016323; C:basolateral plasma membrane; IBA:GO_Central.
DR GO; GO:0015106; F:bicarbonate transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015108; F:chloride transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0019531; F:oxalate transmembrane transporter activity; IBA:GO_Central.
DR GO; GO:0015116; F:sulfate transmembrane transporter activity; IBA:GO_Central.
DR CDD; cd07042; STAS_SulP_like_sulfate_transporter; 1.
DR Gene3D; 3.30.750.24; STAS domain; 1.
DR InterPro; IPR011547; SLC26A/SulP_dom.
DR InterPro; IPR001902; SLC26A/SulP_fam.
DR InterPro; IPR002645; STAS_dom.
DR InterPro; IPR036513; STAS_dom_sf.
DR NCBIfam; TIGR00815; sulP; 1.
DR PANTHER; PTHR11814:SF99; SOLUTE CARRIER FAMILY 26 MEMBER 10; 1.
DR PANTHER; PTHR11814; SULFATE TRANSPORTER; 1.
DR Pfam; PF01740; STAS; 1.
DR Pfam; PF00916; Sulfate_transp; 1.
DR SUPFAM; SSF52091; SpoIIaa-like; 1.
DR PROSITE; PS50801; STAS; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU362052};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Transmembrane {ECO:0000256|ARBA:ARBA00022692,
KW ECO:0000256|RuleBase:RU362052};
KW Transmembrane helix {ECO:0000256|ARBA:ARBA00022989,
KW ECO:0000256|RuleBase:RU362052}; Transport {ECO:0000256|RuleBase:RU362052}.
FT TRANSMEM 94..113
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 120..144
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 191..220
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 354..377
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT TRANSMEM 484..512
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU362052"
FT DOMAIN 540..666
FT /note="STAS"
FT /evidence="ECO:0000259|PROSITE:PS50801"
SQ SEQUENCE 682 AA; 74225 MW; 3601C2643BB9747F CRC64;
MSGLRSTRTC PGLGEASDLK YPLGSKFREP LTQARFQQLF GDAEQDSELR AEPRWSRLRR
QWRRRRASAC SGPGAWRLLL ARLPPLRWLP HYRWRAWLLG DAVAGVTVGI VHVPQGMAFA
LLTSVPPVFG LYTSFFPVLI YTLLGTGRHL STGTFAVLSL MTGSAVERLV PEPLERNLSA
IEREQLDAQR VGAAAAMAFG SGALMLGMFA LQLGVLATFL SEPVVKALTS GAALHVLVSQ
LPSLLGLPLP RQIGCFALFK TLAAVLTELP RSSPAELTIS ALSLALLVPV KELNVRFRDR
LPTPIPGEIV MVLLASVLCF TSSLDTRYNV QIVGLLPGGF PQPLLPSLAE LPRILVDSLP
MAMVTFAVSA SLASIYADKY SYTIDSNQEL LAHGVSNLIS SFFSCFPNSA TLATTSLLVD
AGGNTQLAGL FSCMVVLSVL LWLGPFFYYL PKAVLACINI SSMRQMFFQM RELPQLWRIS
RVDFAVWMVT WVAVVTLSVD LGLAVGVVFS MMTVVCRTQR IQCLALGLAE GTELYRPLRE
SHKLLQVPGL LVLSYPTPLY FGTRGQFRRI LEWHLRLGEG GQEAPKTDDP PDAVAEPVRV
VVLDCSGVPF VDAAGARDVV QLASRCRDAG IHLLLAHAGT LTQAGLLDRV SPEQLFVSVQ
DAAAYALETL ELSGPKTCTV WV
//
