ID A0A287A5K6_PIG Unreviewed; 898 AA.
AC A0A287A5K6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 33.
DE SubName: Full=LIM and calponin homology domains 1 {ECO:0000313|Ensembl:ENSSSCP00000039151.2};
GN Name=LIMCH1 {ECO:0000313|Ensembl:ENSSSCP00000039151.2,
GN ECO:0000313|VGNC:VGNC:89724};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000039151.2, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000039151.2, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000039151.2,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000039151.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A287A5K6; -.
DR Ensembl; ENSSSCT00000057116.2; ENSSSCP00000039151.2; ENSSSCG00000008799.5.
DR VGNC; VGNC:89724; LIMCH1.
DR GeneTree; ENSGT00950000183159; -.
DR ChiTaRS; LIMCH1; pig.
DR Proteomes; UP000008227; Chromosome 8.
DR Bgee; ENSSSCG00000008799; Expressed in skeletal muscle tissue and 42 other cell types or tissues.
DR ExpressionAtlas; A0A287A5K6; baseline and differential.
DR GO; GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
DR CDD; cd08368; LIM; 1.
DR Gene3D; 2.10.110.10; Cysteine Rich Protein; 1.
DR InterPro; IPR031865; DUF4757.
DR InterPro; IPR001781; Znf_LIM.
DR PANTHER; PTHR15551:SF3; LIM AND CALPONIN HOMOLOGY DOMAINS-CONTAINING PROTEIN 1; 1.
DR PANTHER; PTHR15551; LIM DOMAIN ONLY 7; 1.
DR Pfam; PF15949; DUF4757; 1.
DR Pfam; PF00412; LIM; 1.
DR SMART; SM00132; LIM; 1.
DR PROSITE; PS00478; LIM_DOMAIN_1; 1.
DR PROSITE; PS50023; LIM_DOMAIN_2; 1.
PE 1: Evidence at protein level;
KW LIM domain {ECO:0000256|ARBA:ARBA00023038, ECO:0000256|PROSITE-
KW ProRule:PRU00125}; Metal-binding {ECO:0000256|PROSITE-ProRule:PRU00125};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A287A5K6};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Zinc {ECO:0000256|PROSITE-ProRule:PRU00125}.
FT DOMAIN 826..892
FT /note="LIM zinc-binding"
FT /evidence="ECO:0000259|PROSITE:PS50023"
FT REGION 13..165
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 214..245
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 354..390
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 403..541
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 581..604
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 635..657
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 669..751
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 766..789
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 13..59
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 60..74
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 82..109
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 354..371
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 405..420
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 445..459
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 473..495
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 497..526
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 527..541
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 581..600
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 670..699
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 700..716
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 774..789
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 898 AA; 101934 MW; 7AFBFEF9CF0E46C9 CRC64;
MLRHWREQGF YYNTRETDDI ESPKRSIRDS GYIDCWDSER SDSLSPPRHG RDDSFDSLDS
FGSRSRQTPS PDVVLRGSSD GRGSDSESDL PHRKLPDVKK DDMSARRTSH GEPKSAVPFN
QYLPNKSNQT AYVPAPLRKK KAEREEYRKS WSTATSPLGG ERPFRSTSMF DMRCEEEAAV
QPHSRARQEQ LQLINNQLRE EDDKWQDDLA RWKSRRRSAS QDLIKKEEER KKMEKLLAGE
DGTRERRKSI KTYREIVQEK ERRERELHEA YKNARSQEEA EGILQQYIER FTISEAVLER
LEMPKILERS HSAEPNSSSF LDDPNPMKYL RQQSLPPPKF TATVETTITR TSVPDASMSA
GSGSPSKTVT PKAVPMLTPK PYSQPKNSQE VLKTFKVDGK VSMNGETVHG DEEKERECPP
GAHTPSLTKS QMFEGVARVH GSPVELKQDN NSIEINIKKP SSLPQELPAT IEETDANRQE
DESDGEKREK GNTDIVSPEP QHFTTTVTRS SPTVAFVELS SSPQLKNEVP EEKEQKKLEN
EMSGKVELVL SQKVVKPKSP EPEATLTFPF LDKMPETNQL HLPNLNSQVD SPSSEKSPVT
TPFKFWAWDP EEERRRQEKW QQEQERLLQE RYQKEQDKLK EEWEKAQKEV EEEERRYYEE
ERKIIEDTVV PFTISSSSAD QLSTSSSMTE GSGTVTKMDL ENCQEEEQET RQKKPLQGDN
SDLLLKTGDG DPLEEKGSLT QGVLTHSENP ASKGIYQDHQ LDAEAGASHC GMNPQPAQDP
SQNQQVSNPP MHILEDVKPK TLPLDKSINH QIESPSERRK SISGKKLCSS CGLPLGKGAA
MIIETLSLYF HIQCFRCGIC KGQLGDAVSG TDVRIRNGLL NCNDCYMRSR SAGQPTTL
//
