ID A0A287A6H6_PIG Unreviewed; 701 AA.
AC A0A287A6H6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 3.
DT 27-MAR-2024, entry version 32.
DE SubName: Full=Aryl hydrocarbon receptor nuclear translocator 2 {ECO:0000313|Ensembl:ENSSSCP00000039475.3};
GN Name=ARNT2 {ECO:0000313|Ensembl:ENSSSCP00000039475.3};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000039475.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000039475.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000039475.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000039475.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A287A6H6; -.
DR Ensembl; ENSSSCT00000048996.3; ENSSSCP00000039475.3; ENSSSCG00000040288.3.
DR GeneTree; ENSGT00940000158198; -.
DR Proteomes; UP000008227; Chromosome 7.
DR Bgee; ENSSSCG00000040288; Expressed in prefrontal cortex and 27 other cell types or tissues.
DR ExpressionAtlas; A0A287A6H6; baseline and differential.
DR GO; GO:0005737; C:cytoplasm; IEA:InterPro.
DR GO; GO:0005634; C:nucleus; IEA:InterPro.
DR GO; GO:0005667; C:transcription regulator complex; IEA:InterPro.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0046983; F:protein dimerization activity; IEA:InterPro.
DR CDD; cd18947; bHLH-PAS_ARNT; 1.
DR CDD; cd00130; PAS; 2.
DR Gene3D; 4.10.280.10; Helix-loop-helix DNA-binding domain; 1.
DR Gene3D; 3.30.450.20; PAS domain; 2.
DR InterPro; IPR011598; bHLH_dom.
DR InterPro; IPR036638; HLH_DNA-bd_sf.
DR InterPro; IPR001067; Nuc_translocat.
DR InterPro; IPR001610; PAC.
DR InterPro; IPR000014; PAS.
DR InterPro; IPR035965; PAS-like_dom_sf.
DR InterPro; IPR013767; PAS_fold.
DR NCBIfam; TIGR00229; sensory_box; 1.
DR PANTHER; PTHR23042:SF6; ARYL HYDROCARBON RECEPTOR NUCLEAR TRANSLOCATOR 2; 1.
DR PANTHER; PTHR23042; CIRCADIAN PROTEIN CLOCK/ARNT/BMAL/PAS; 1.
DR Pfam; PF00010; HLH; 1.
DR Pfam; PF00989; PAS; 1.
DR Pfam; PF14598; PAS_11; 1.
DR PRINTS; PR00785; NCTRNSLOCATR.
DR SMART; SM00353; HLH; 1.
DR SMART; SM00086; PAC; 1.
DR SMART; SM00091; PAS; 2.
DR SUPFAM; SSF47459; HLH, helix-loop-helix DNA-binding domain; 1.
DR SUPFAM; SSF55785; PYP-like sensor domain (PAS domain); 2.
DR PROSITE; PS50888; BHLH; 1.
DR PROSITE; PS50112; PAS; 2.
PE 4: Predicted;
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT DOMAIN 52..105
FT /note="BHLH"
FT /evidence="ECO:0000259|PROSITE:PS50888"
FT DOMAIN 123..198
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT DOMAIN 331..382
FT /note="PAS"
FT /evidence="ECO:0000259|PROSITE:PS50112"
FT REGION 24..65
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 537..686
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 35..65
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 537..667
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 701 AA; 76989 MW; 5CA3EFB49A7C2AF8 CRC64;
MASDIPGSVT LPVAPMAATG QVRMAGAMPA RGGKRRSGMD FDDEDGEGPS KFSRENHSEI
ERRRRNKMTQ YITELSDMVP TCSALARKPD KLTILRMAVS HMKSMRGTGN KSTDGAYKPS
FLTEQELKHL ILEAADGFLF VVAAETGRVI YVSDSVTPVL NQPQSEWFGS TLYEQVHPDD
VEKLREQLCT SENSMTGRIL DLKTGTVKKE GQQSSMRMCM GSRRSFICRM RCGNAPLDHL
PLNRITTMRK RFRNGLGPVK EGEAQYAVVH CTGYIKAWPP AGMTIPEEDA DVGQGSKYCL
VAIGRLQVTS SPVCMDMSGM SVPTEFLSRH NSDGIITFVD PRCISVIGYQ PQDLLGKDIL
EFCHSEDQSH LRESFQQVVK LKGQVLSVMY RFRTKNREWV LIRTSSFTFQ NPYSDEIEYI
ICTNTNVKQL QQQQAELEVH QRDGLSSYDL SQVPVPNLPA GVHEAGKSVE KADAIFSQER
DPRFAEMFAG ISASEKKMMS SASAAGSQQI YSQGSPFPAG HSGKAFSSSV VHVPGVNDIQ
SSSSTSQNMS QISRQLNQSQ VAWTGSRPPF PGQSSKTQSS PFGIGTSHTY PADPSSYSPL
SSPATSSPSG NAYSSLANRT PGFAESGQSS GQFQGRPSEV WSQWQSQHHG QQSGEQHSHQ
QPGQTEVFQD MLPMPGDPTQ GTGNYNIEDF ADLGMFPPFS E
//
