ID   A0A287ABL8_PIG          Unreviewed;      1380 AA.
AC   A0A287ABL8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   22-NOV-2017, sequence version 1.
DT   27-MAR-2024, entry version 27.
DE   SubName: Full=Uveal autoantigen with coiled-coil domains and ankyrin repeats {ECO:0000313|Ensembl:ENSSSCP00000041357.1};
GN   Name=UACA {ECO:0000313|Ensembl:ENSSSCP00000041357.1,
GN   ECO:0000313|VGNC:VGNC:94625};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000041357.1, ECO:0000313|Proteomes:UP000008227};
RN   [1] {ECO:0000313|Ensembl:ENSSSCP00000041357.1, ECO:0000313|Proteomes:UP000008227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000041357.1,
RC   ECO:0000313|Proteomes:UP000008227};
RG   Porcine genome sequencing project;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSSCP00000041357.1}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
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DR   Ensembl; ENSSSCT00000037935.3; ENSSSCP00000041357.1; ENSSSCG00000004973.5.
DR   VGNC; VGNC:94625; UACA.
DR   GeneTree; ENSGT00940000157475; -.
DR   Proteomes; UP000008227; Chromosome 1.
DR   Bgee; ENSSSCG00000004973; Expressed in longissimus thoracis muscle and 45 other cell types or tissues.
DR   ExpressionAtlas; A0A287ABL8; baseline and differential.
DR   Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 2.
DR   InterPro; IPR002110; Ankyrin_rpt.
DR   InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR   PANTHER; PTHR24129; ANKYCORBIN; 1.
DR   PANTHER; PTHR24129:SF2; UVEAL AUTOANTIGEN WITH COILED-COIL DOMAINS AND ANKYRIN REPEATS; 1.
DR   Pfam; PF00023; Ank; 1.
DR   Pfam; PF12796; Ank_2; 1.
DR   Pfam; PF13637; Ank_4; 1.
DR   PRINTS; PR01415; ANKYRIN.
DR   SMART; SM00248; ANK; 7.
DR   SUPFAM; SSF48403; Ankyrin repeat; 1.
DR   SUPFAM; SSF90257; Myosin rod fragments; 1.
DR   PROSITE; PS50297; ANK_REP_REGION; 4.
DR   PROSITE; PS50088; ANK_REPEAT; 5.
PE   1: Evidence at protein level;
KW   ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW   Coiled coil {ECO:0000256|SAM:Coils};
KW   Proteomics identification {ECO:0007829|PeptideAtlas:A0A287ABL8};
KW   Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW   Repeat {ECO:0000256|ARBA:ARBA00022737}.
FT   REPEAT          54..86
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          87..119
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          120..152
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          153..185
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   REPEAT          186..218
FT                   /note="ANK"
FT                   /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT   COILED          260..336
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          417..476
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          503..558
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          600..645
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          669..696
FT                   /evidence="ECO:0000256|SAM:Coils"
FT   COILED          746..1347
FT                   /evidence="ECO:0000256|SAM:Coils"
SQ   SEQUENCE   1380 AA;  158578 MW;  8F382CF6EB13730D CRC64;
     MMNCWFSCAP KNRHAADWNK YDDRLMKAAE RGDVEKVSSI LAKKGVNPGK LDVEGRSAFH
     VVASKGNLEC LNAILIHGVD ITIGDTAGRN ALHLAAKYGH ALCLQKLLQY NCPTEHVDLQ
     GRTALHDAAM ADCPSSIQLL CDHGASVNAK DVDGRTPLVL ATQMCRPTIC QLLIDRGADI
     NSRDKQNRTA LMLGCEYGCK DAVEVLMKNG ADVTLLDALG HDCFYYARIG DNLDILTLLK
     TASENTNRGR ELWKKGPSLQ QDLEIENEDL KERLRKIQQE QRILLDKVNG LQLQLNEEVM
     VADDLKSEKE KLKSLLATKE KQQEESLRTI EALKNRFKYF ESDHLGSGGH FSNRKEDMLL
     TQGQMYMTDS QCTSLGMPAH MQSRSMLRPL ELSLPNQTSY SENEILKKEL EAMRTFCESA
     KQDRLKLQNE LAHKVAECKA LALECERVKE DSDEQIKQLE DALKDVQKRM YESEGKVKQM
     QTHFLALKEH LTSEASTGNH RLMEELKDQL RDMKVKYEGA SAEVGKLRNQ IKQNEMLVEE
     FKRDEGKLME EKKQLQKELG MCDVEREQRV RKVTEMEGQL KDLSAKLALS ISAEKFESMK
     SLLSSEVNEK ARKLAEMEGE YERSLSEIRS LKRELENSKA KLAQHVKPEE HEQLKSRLEQ
     KSGELGKKIT ELTSKNQMLQ KEIEKVHLDN KLLNQQVHNL TTEMKNHYVP LKVSEEMKKS
     HDVVVNDLNK KLSDVTHKYT EKKLEMEKLV MENASLSKNV SRLETVFVPP EKHEKEIMAL
     KSSIAELKKQ LAELNKKCDE DQEKIYSLVS ENTNLKKAMS NQYVPVKTHE EIKTALSSTL
     DKANRELVDV KKKCENINQE FVKMKDENET LKRSLENTQN QVKAEYISLR EHEEKMSAVR
     KSMKKVQDSS AEVLANYKKG QEEIVTLHAE IEAQKRELDT IQECIKLKYA PIISFEECER
     KFKATEKELK EQLSEQTQKC NVTEEEVKKC KQENDKLKKE IFTLQKDLKD KNVLVENSHE
     MERAFSRKTE ELNRQLKDLL QKYTEVKGEK EKLAEENAKQ SSEILAAQTL LQKQHMPLEQ
     VEALKKSLNS TIETLKEELK TKQRCYEKEQ QTVTQLRQML ENQKNSSVPL AEHLQIKEAF
     EKEVGIIKAS LREKEEESQN KTEEVSRLQS EIQNTKQTLK KLETREVVDL SKYKATKSDL
     ETQISNLNEK LANLNRKYEE VCEEVLHAKK KELSAKDEKE LLHFSIEQEI KDQQERCDKS
     LTTITELQRR IQESAKQIEA KDNKITELLN DVERLKQALN GLSQLTYSSG SPSKRQSQLI
     ESLQHQVKSL QQQLADADRQ HQEVIAIYRT HLLSAAQGHM DEDVQAALLQ IIQMRQGLVC
//