ID A0A287AC28_PIG Unreviewed; 436 AA.
AC A0A287AC28;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 3.
DT 27-MAR-2024, entry version 31.
DE RecName: Full=Lysine demethylase 4D {ECO:0008006|Google:ProtNLM};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000041523.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000041523.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000041523.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000041523.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR AlphaFoldDB; A0A287AC28; -.
DR STRING; 9823.ENSSSCP00000041523; -.
DR PaxDb; 9823-ENSSSCP00000015886; -.
DR Ensembl; ENSSSCT00000047992.3; ENSSSCP00000041523.3; ENSSSCG00000031376.3.
DR eggNOG; KOG0958; Eukaryota.
DR GeneTree; ENSGT00940000162152; -.
DR InParanoid; A0A287AC28; -.
DR Reactome; R-SSC-3214842; HDMs demethylate histones.
DR Proteomes; UP000008227; Chromosome 9.
DR Bgee; ENSSSCG00000031376; Expressed in testis and 3 other cell types or tissues.
DR GO; GO:0000785; C:chromatin; IBA:GO_Central.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0032454; F:histone H3K9 demethylase activity; IBA:GO_Central.
DR GO; GO:0006338; P:chromatin remodeling; IBA:GO_Central.
DR GO; GO:0010468; P:regulation of gene expression; IBA:GO_Central.
DR Gene3D; 2.60.120.650; Cupin; 1.
DR InterPro; IPR003347; JmjC_dom.
DR InterPro; IPR003349; JmjN.
DR PANTHER; PTHR10694; LYSINE-SPECIFIC DEMETHYLASE; 1.
DR PANTHER; PTHR10694:SF21; LYSINE-SPECIFIC DEMETHYLASE 4D; 1.
DR Pfam; PF02373; JmjC; 1.
DR Pfam; PF02375; JmjN; 1.
DR SMART; SM00558; JmjC; 1.
DR SMART; SM00545; JmjN; 1.
DR SUPFAM; SSF51197; Clavaminate synthase-like; 1.
DR PROSITE; PS51184; JMJC; 1.
DR PROSITE; PS51183; JMJN; 1.
PE 4: Predicted;
KW Chromatin regulator {ECO:0000256|ARBA:ARBA00022853};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 18..60
FT /note="JmjN"
FT /evidence="ECO:0000259|PROSITE:PS51183"
FT DOMAIN 146..312
FT /note="JmjC"
FT /evidence="ECO:0000259|PROSITE:PS51184"
SQ SEQUENCE 436 AA; 49870 MW; 537093AE8E22CAC3 CRC64;
MEAMKSKANY VQNPSCSIMI FHPTKEEFND FDKYIAYIES QGAHRAGLAK VIPPKGWKAR
QTYEDISDIS IAAPLQQEAS GKAGVFTQYH RKKKAMTVSE YCHLANSEKY QAPPHLDFED
LEQTYWKTRL YGSPIYGADV SGSLFDENTK QWNLGHLGTI QDLLEQECGV AIDGVNSPYL
YFGMWKTGFA WHTEDMDLYS LNFLHFGEPK TWYAVPPAHG RRLERLAREL FPGPARGCEA
FLRHKVALIS PTVLKAQGIP FGRVTQEAGE FMVTFPYGYH SGFNHGFNCA EAINFATPRW
VDYGKVASQC SCGEARVVFS MDAFVRILQP ERYELWKRGQ DRVALEHTEH LSSPGSLELS
AWREVRSLRL APCPRQSFGY LQVPGLARKA LLCGRWWYWL HGLYQILQSL FFLPDFFGNL
LTPARHPLTD FIHWTR
//
