ID A0A287ADQ9_PIG Unreviewed; 1602 AA.
AC A0A287ADQ9;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 3.
DT 27-MAR-2024, entry version 34.
DE SubName: Full=ADAMTS like 3 {ECO:0000313|Ensembl:ENSSSCP00000041941.3};
GN Name=ADAMTSL3 {ECO:0000313|Ensembl:ENSSSCP00000041941.3,
GN ECO:0000313|VGNC:VGNC:85092};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000041941.3, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000041941.3, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000041941.3,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000041941.3}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
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DR Ensembl; ENSSSCT00000045912.3; ENSSSCP00000041941.3; ENSSSCG00000001793.5.
DR VGNC; VGNC:85092; ADAMTSL3.
DR GeneTree; ENSGT00940000158143; -.
DR Proteomes; UP000008227; Chromosome 7.
DR Bgee; ENSSSCG00000001793; Expressed in stomach and 39 other cell types or tissues.
DR ExpressionAtlas; A0A287ADQ9; baseline and differential.
DR GO; GO:0005576; C:extracellular region; IEA:UniProtKB-KW.
DR GO; GO:0030198; P:extracellular matrix organization; IEA:InterPro.
DR CDD; cd00096; Ig; 1.
DR Gene3D; 2.60.120.830; -; 1.
DR Gene3D; 2.60.40.10; Immunoglobulins; 3.
DR Gene3D; 2.20.100.10; Thrombospondin type-1 (TSP1) repeat; 11.
DR InterPro; IPR013273; ADAMTS/ADAMTS-like.
DR InterPro; IPR045371; ADAMTS_CR_3.
DR InterPro; IPR007110; Ig-like_dom.
DR InterPro; IPR036179; Ig-like_dom_sf.
DR InterPro; IPR013783; Ig-like_fold.
DR InterPro; IPR013098; Ig_I-set.
DR InterPro; IPR003599; Ig_sub.
DR InterPro; IPR003598; Ig_sub2.
DR InterPro; IPR000884; TSP1_rpt.
DR InterPro; IPR036383; TSP1_rpt_sf.
DR PANTHER; PTHR13723; ADAMTS A DISINTEGRIN AND METALLOPROTEASE WITH THROMBOSPONDIN MOTIFS PROTEASE; 1.
DR PANTHER; PTHR13723:SF281; NO LONG NERVE CORD, ISOFORM C; 1.
DR Pfam; PF19236; ADAMTS_CR_3; 1.
DR Pfam; PF07679; I-set; 2.
DR Pfam; PF13927; Ig_3; 1.
DR Pfam; PF19030; TSP1_ADAMTS; 10.
DR Pfam; PF00090; TSP_1; 1.
DR PRINTS; PR01857; ADAMTSFAMILY.
DR SMART; SM00409; IG; 3.
DR SMART; SM00408; IGc2; 3.
DR SMART; SM00209; TSP1; 11.
DR SUPFAM; SSF48726; Immunoglobulin; 3.
DR SUPFAM; SSF82895; TSP-1 type 1 repeat; 11.
DR PROSITE; PS50835; IG_LIKE; 3.
DR PROSITE; PS50092; TSP1; 9.
PE 4: Predicted;
KW Disulfide bond {ECO:0000256|ARBA:ARBA00023157,
KW ECO:0000256|PIRSR:PIRSR613273-3};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Repeat {ECO:0000256|ARBA:ARBA00022737};
KW Secreted {ECO:0000256|ARBA:ARBA00022525}; Signal {ECO:0000256|SAM:SignalP}.
FT SIGNAL 1..34
FT /evidence="ECO:0000256|SAM:SignalP"
FT CHAIN 35..1602
FT /evidence="ECO:0000256|SAM:SignalP"
FT /id="PRO_5036495581"
FT DOMAIN 911..1007
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1201..1295
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DOMAIN 1300..1399
FT /note="Ig-like"
FT /evidence="ECO:0000259|PROSITE:PS50835"
FT DISULFID 99..130
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 103..135
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
FT DISULFID 114..120
FT /evidence="ECO:0000256|PIRSR:PIRSR613273-3"
SQ SEQUENCE 1602 AA; 178072 MW; 6AE7CD843CBDD28D CRC64;
MVTSEPPRRL DPMASWKSPW WLLIWMVFTH SALLQTTAEK SPGAYFLPEF ALSPQGSFLE
DTTGEQFLTY RYDDQTSRNT RSDEDKDSNW DAWGDWSDCS RTCGGGASYS LRRCLTGRNC
EGQNIRYKTC SNHDCPPDAE DFRAQQCSAY NDVQYQGRYY EWLPRYNDPT APCALKCHAK
GQNLVVELAP KVLDGTRCNT DSLDMCISGI CQAVGCDRQL GSHAKEDNCG VCAGDGATCR
LVRGQSKSNV SPEKREENVI AVPLGSRSVR ITVKGPAHLF IESKTLQGSK GEHSFNSPGV
FVVENTTVEF QRGSERQTFK IPGPLMADFI FKTRYTAAKD SVVQFFFYQP ISHQWRQTDF
FPCTVTCGGG YQLNSAECVD IRLKRVVPDH YCHYYPENVK PKPKLKECSM DPCPSSDGFK
EIMPYDHFQP LPRWEHNPWT ACSVSCGGGI QRRSFVCVEE SMHGEILQVE EWKCMYAPKP
KVMQTCNLFD CPKWIAMEWS QCTVTCGRGL RYRVVLCINH RGQHVGGCNP QLKLHIKEEC
IIPIPCYKPK EKSPVEAKLP WLKQAQELEE TRIATEEPMF IPEPWSACST TCGPGIQVRE
VKCRVLLTFT QTETELPEEE CDGPPLPTER PCLLEPCDES PTSREPAATV SLQEKDSEMT
YDWEYAGFTP CTATCLGGRQ EAIAVCLHIQ TQQTVNDTLC DTVHRPPAMS QACNTEPCPP
RWHTGSWGPC SATCGVGIQT REVYCVHPGE SPSPPEECRE ERPHALQACN QFDCPPSWHI
EEWQQCSRTC GGGTQNRRVT CRQLLTDGSF LNLSDELCQG PKASSHKSCA RTDCPPHVTM
GDWSKCSVTC GVGTQRRKQV CQRLTAKGRR VPLSETMCRH LPGAPLVRSC QMPVCRKMKP
EVKTKLGEQG PQILGVQRVY IQTREEKRIN LTVGSRAYLL PNTSVIIKCP VRRFQKSLIQ
WEKDGRCLQN SKRLGITKSG SLKIHSLTAP DIGTYQCIAG SAKETVVLKL IGTDNRLIAP
PALRGHLMEY PGMDHNEANN LGATWHKMRQ MWSTKNELYL DDGQINNQPL LRALLGHCSN
SAGNANSWEF KNKQFEAAVK QGAYSMDTAQ FDEMIRNMSQ LIETGEVSDD LASQVIYHLV
AELAKAQAPA HAPWRGIPEE APPAAHLRGE TGSVPQSSNV KDSGKLTFKP KGPVLLRQSQ
PTSISFNKTV NARIGDTVYI TRRTEVINIL CELDTPSEAT YMWTKDGASL QPSAKVILDG
MGKIQIQKPT KKDQGVYGCS VANHLGSDVE SSSVLYAEAP VILSIERNIT RPEHSHLSVV
IGGIVEAPLR ANVTIQCPVK GIPQPNITWL KKGGSLSDSI SLLFNGSLLL QNVSLENEGT
YVCTAINALG KAKATSVLHL LEPFWELGNW THCSATCGHL GARVRRPQCV MANGQEVSES
LCNHLQKPLA GYQPCNLQDC PSRWFTSTWS QCSVSCGEGF RSRQVTCKRT RANGTVQVMS
PRACALKDKP LGRRPCASHP CVQGAIEPGS QCPGRCLGHA VRMQQPHVIC QLHNSSDSDC
DDRRSLYSSS QHGQVLLDYD FFFFFCIFRA APSAYGGSQA KG
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