ID A0A287AQI5_PIG Unreviewed; 306 AA.
AC A0A287AQI5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 27.
DE RecName: Full=Tetraspanin {ECO:0000256|RuleBase:RU361218};
GN Name=TSPAN17 {ECO:0000313|Ensembl:ENSSSCP00000046139.1,
GN ECO:0000313|VGNC:VGNC:94506};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000046139.1, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000046139.1, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000046139.1,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000046139.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000256|ARBA:ARBA00004141,
CC ECO:0000256|RuleBase:RU361218}; Multi-pass membrane protein
CC {ECO:0000256|ARBA:ARBA00004141, ECO:0000256|RuleBase:RU361218}.
CC -!- SIMILARITY: Belongs to the tetraspanin (TM4SF) family.
CC {ECO:0000256|ARBA:ARBA00006840, ECO:0000256|RuleBase:RU361218}.
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DR RefSeq; XP_005661517.2; XM_005661460.2.
DR AlphaFoldDB; A0A287AQI5; -.
DR SMR; A0A287AQI5; -.
DR STRING; 9823.ENSSSCP00000046139; -.
DR PaxDb; 9823-ENSSSCP00000014941; -.
DR Ensembl; ENSSSCT00000050435.3; ENSSSCP00000046139.1; ENSSSCG00000014051.5.
DR GeneID; 100523050; -.
DR CTD; 26262; -.
DR VGNC; VGNC:94506; TSPAN17.
DR GeneTree; ENSGT00940000155429; -.
DR InParanoid; A0A287AQI5; -.
DR OrthoDB; 2879418at2759; -.
DR Proteomes; UP000008227; Chromosome 2.
DR Bgee; ENSSSCG00000014051; Expressed in oocyte and 45 other cell types or tissues.
DR ExpressionAtlas; A0A287AQI5; baseline and differential.
DR GO; GO:0016020; C:membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0019899; F:enzyme binding; IEA:Ensembl.
DR GO; GO:0072594; P:establishment of protein localization to organelle; IEA:Ensembl.
DR GO; GO:0051043; P:regulation of membrane protein ectodomain proteolysis; IEA:Ensembl.
DR CDD; cd03159; TM4SF9_like_LEL; 1.
DR Gene3D; 1.10.1450.10; Tetraspanin; 1.
DR InterPro; IPR018499; Tetraspanin/Peripherin.
DR InterPro; IPR000301; Tetraspanin_animals.
DR InterPro; IPR018503; Tetraspanin_CS.
DR InterPro; IPR008952; Tetraspanin_EC2_sf.
DR PANTHER; PTHR19282; TETRASPANIN; 1.
DR PANTHER; PTHR19282:SF470; TETRASPANIN-17; 1.
DR Pfam; PF00335; Tetraspanin; 1.
DR PIRSF; PIRSF002419; Tetraspanin; 1.
DR PRINTS; PR00259; TMFOUR.
DR SUPFAM; SSF48652; Tetraspanin; 1.
DR PROSITE; PS00421; TM4_1; 1.
PE 3: Inferred from homology;
KW Membrane {ECO:0000256|ARBA:ARBA00023136, ECO:0000256|RuleBase:RU361218};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW Transmembrane {ECO:0000256|RuleBase:RU361218};
KW Transmembrane helix {ECO:0000256|RuleBase:RU361218}.
FT TRANSMEM 20..44
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 64..86
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 98..117
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
FT TRANSMEM 235..256
FT /note="Helical"
FT /evidence="ECO:0000256|RuleBase:RU361218"
SQ SEQUENCE 306 AA; 33938 MW; 5089319730AAA1CA CRC64;
MPGKHQHFQE PEVGCCGKYF LFGFNIVFWV LGALFLAIGL WAWGEKGVLS NISALTDLGG
LDPVWLFVVV GGIMSVLGFA GCIGALRENT FLLKFFSVFL GLIFFLELAT GILAFVFKDW
IRDQLNLFIN NNVKAYRDDI DLQNLIDFAQ EYWSCCGARG PNDWNLNIYF NCTDLNPSRE
RCGVPFSCCV RDPAEDVLNT QCGYDVRLKL ELEQQGSIHT KGCVGQFEKW LQDNLIVVAG
VFVGIALLQI FGICLAQNLV SDIKAVKANW WCRPVVKNCK LRGSSHCGSV GSAMFGSAGM
QVQFPG
//
