ID A0A287AVR5_PIG Unreviewed; 271 AA.
AC A0A287AVR5;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 29.
DE SubName: Full=HLF transcription factor, PAR bZIP family member {ECO:0000313|Ensembl:ENSSSCP00000048229.2};
GN Name=HLF {ECO:0000313|Ensembl:ENSSSCP00000048229.2,
GN ECO:0000313|VGNC:VGNC:88896};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000048229.2, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000048229.2, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000048229.2,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000048229.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000256|ARBA:ARBA00004123}.
CC -!- SIMILARITY: Belongs to the bZIP family. PAR subfamily.
CC {ECO:0000256|ARBA:ARBA00009208}.
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DR AlphaFoldDB; A0A287AVR5; -.
DR Ensembl; ENSSSCT00000055725.2; ENSSSCP00000048229.2; ENSSSCG00000017604.5.
DR VGNC; VGNC:88896; HLF.
DR GeneTree; ENSGT00940000156555; -.
DR Proteomes; UP000008227; Chromosome 12.
DR Bgee; ENSSSCG00000017604; Expressed in cerebellum and 46 other cell types or tissues.
DR ExpressionAtlas; A0A287AVR5; baseline and differential.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; IEA:InterPro.
DR GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IEA:InterPro.
DR CDD; cd14695; bZIP_HLF; 1.
DR Gene3D; 1.20.5.170; -; 1.
DR InterPro; IPR004827; bZIP.
DR InterPro; IPR046347; bZIP_sf.
DR InterPro; IPR040223; PAR_bZIP.
DR PANTHER; PTHR11988:SF28; HEPATIC LEUKEMIA FACTOR; 1.
DR PANTHER; PTHR11988; THYROTROPH EMBRYONIC FACTOR RELATED; 1.
DR Pfam; PF07716; bZIP_2; 1.
DR SMART; SM00338; BRLZ; 1.
DR SUPFAM; SSF57959; Leucine zipper domain; 1.
DR PROSITE; PS50217; BZIP; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Nucleus {ECO:0000256|ARBA:ARBA00023242};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 201..264
FT /note="BZIP"
FT /evidence="ECO:0000259|PROSITE:PS50217"
FT REGION 20..45
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 69..143
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 233..267
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 128..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 271 AA; 30237 MW; 15220EA23676B8A5 CRC64;
MRSLGIGIVL IAAVTFSKDK DKEKKLDDES NSPTVPQSAF LGPTLWDKTL PYDGDTFQLE
YMDLEEFLSE NGIPPSPSQH DHSPHPPGLQ PASSAAPSVM DLSSRASAPI HPGIPSPTCM
QSPIRPGQLL PANRNTPSPI DPDTIQVPVG YEPDPADLAL SSIPGQEMFD PRKRKFSEEE
LKPQPMIKKA RKVFIPDDLK DDKYWARRRK NNMAAKRSRD ARRLKENQIA IRASFLEKEN
SALRQEVADL RKELGKCKNI LAKYEARHGP L
//
