ID A0A287AYX6_PIG Unreviewed; 451 AA.
AC A0A287AYX6;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 11-DEC-2019, sequence version 2.
DT 27-MAR-2024, entry version 28.
DE RecName: Full=IF rod domain-containing protein {ECO:0000259|PROSITE:PS51842};
GN Name=LOC100523123 {ECO:0000313|Ensembl:ENSSSCP00000049351.2};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000049351.2, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000049351.2, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000049351.2,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|Ensembl:ENSSSCP00000049351.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SIMILARITY: Belongs to the intermediate filament family.
CC {ECO:0000256|RuleBase:RU000685}.
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DR AlphaFoldDB; A0A287AYX6; -.
DR Ensembl; ENSSSCT00000038639.2; ENSSSCP00000049351.2; ENSSSCG00000052051.1.
DR GeneTree; ENSGT00940000154026; -.
DR Proteomes; UP000008227; Chromosome 5.
DR Bgee; ENSSSCG00000022657; Expressed in testis and 2 other cell types or tissues.
DR GO; GO:0045095; C:keratin filament; IEA:InterPro.
DR Gene3D; 1.20.5.170; -; 1.
DR Gene3D; 1.20.5.500; Single helix bin; 1.
DR Gene3D; 1.20.5.1160; Vasodilator-stimulated phosphoprotein; 1.
DR InterPro; IPR018039; IF_conserved.
DR InterPro; IPR039008; IF_rod_dom.
DR InterPro; IPR032444; Keratin_2_head.
DR InterPro; IPR003054; Keratin_II.
DR PANTHER; PTHR45616; GATA-TYPE DOMAIN-CONTAINING PROTEIN; 1.
DR PANTHER; PTHR45616:SF52; KERATIN, TYPE II CUTICULAR HB6; 1.
DR Pfam; PF00038; Filament; 1.
DR Pfam; PF16208; Keratin_2_head; 1.
DR PRINTS; PR01276; TYPE2KERATIN.
DR SMART; SM01391; Filament; 1.
DR SUPFAM; SSF64593; Intermediate filament protein, coiled coil region; 2.
DR PROSITE; PS00226; IF_ROD_1; 1.
DR PROSITE; PS51842; IF_ROD_2; 1.
PE 3: Inferred from homology;
KW Coiled coil {ECO:0000256|ARBA:ARBA00023054, ECO:0000256|SAM:Coils};
KW Intermediate filament {ECO:0000256|ARBA:ARBA00022754,
KW ECO:0000256|RuleBase:RU000685}; Keratin {ECO:0000256|ARBA:ARBA00022744};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT DOMAIN 106..417
FT /note="IF rod"
FT /evidence="ECO:0000259|PROSITE:PS51842"
FT COILED 103..144
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 187..242
FT /evidence="ECO:0000256|SAM:Coils"
FT COILED 308..395
FT /evidence="ECO:0000256|SAM:Coils"
SQ SEQUENCE 451 AA; 50807 MW; 75B67E262F241DAB CRC64;
MTCRSGFSSH TFSCASACGP RPGRCCITAA PYRGISCYRG LTGGFGSRSV GGGFRAGSYG
RSFGYRSGGV VRPSPPCITT VSINECLLTP LNLEIDPNAQ CVKQEEKEQI KCLNNRFAAF
IDKVRFLEQQ NKLLETKLQF YQNRQCCESN LEPLFNGYIE TLRREAELVE ADSGRLASEL
NHVQEVLEGY KKKYEEEVAL RATAENEFVA LKKDVDCAYV RKSDLEANVE ALVQEIDFLR
RLYEEEIRVL QAHISDTSVI VKLDNSRDLN MDNIVAEIKA HYDDIASRSR AEAESWYRSK
CEEIKATVVR HGETLRRTKE EINELNRMIQ RLTAEIENAK CQNSKLEAAV AEAEQQGQVA
LNDAKCKLAE LEAALQKAKQ DMACLIKEYQ EVLNSKLGLD IEIATYRRLL EGEEQSFGGL
FLQTLCFYCL DHGWTSFLEF VELGCVKVLA P
//
