ID A0A287BHM7_PIG Unreviewed; 2032 AA.
AC A0A287BHM7;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 14-DEC-2022, sequence version 2.
DT 27-MAR-2024, entry version 26.
DE SubName: Full=Ankyrin repeat domain 12 {ECO:0000313|Ensembl:ENSSSCP00000055866.2};
DE SubName: Full=Ankyrin repeat domain-containing protein 12 isoform 2 {ECO:0000313|EMBL:HDC23925.1};
DE SubName: Full=Ankyrin repeat domain-containing protein 12 isoform X1 {ECO:0000313|EMBL:HDA39145.1};
GN Name=ANKRD12 {ECO:0000313|Ensembl:ENSSSCP00000055866.2,
GN ECO:0000313|VGNC:VGNC:96906};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000055866.2, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000055866.2, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000055866.2,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:HDA39145.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30723633; DOI=.7717/peerj.6374;
RA Gilbert D.G.;
RT "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL PeerJ 7:E6374-E6374(2019).
RN [3] {ECO:0000313|Ensembl:ENSSSCP00000055866.2}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; DQIR01083669; HDA39145.1; -; Transcribed_RNA.
DR EMBL; DQIR01268447; HDC23925.1; -; Transcribed_RNA.
DR EMBL; DQIR01268448; HDC23926.1; -; Transcribed_RNA.
DR Ensembl; ENSSSCT00000053210.3; ENSSSCP00000055866.2; ENSSSCG00000003682.5.
DR VGNC; VGNC:96906; ANKRD12.
DR GeneTree; ENSGT00940000154742; -.
DR Proteomes; UP000008227; Chromosome 6.
DR Bgee; ENSSSCG00000003682; Expressed in mesenteric lymph node and 43 other cell types or tissues.
DR Gene3D; 1.25.40.20; Ankyrin repeat-containing domain; 1.
DR InterPro; IPR002110; Ankyrin_rpt.
DR InterPro; IPR036770; Ankyrin_rpt-contain_sf.
DR PANTHER; PTHR24149; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12; 1.
DR PANTHER; PTHR24149:SF16; ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 12; 1.
DR Pfam; PF00023; Ank; 1.
DR Pfam; PF12796; Ank_2; 1.
DR PRINTS; PR01415; ANKYRIN.
DR SMART; SM00248; ANK; 3.
DR SUPFAM; SSF48403; Ankyrin repeat; 1.
DR PROSITE; PS50297; ANK_REP_REGION; 3.
DR PROSITE; PS50088; ANK_REPEAT; 3.
PE 4: Predicted;
KW ANK repeat {ECO:0000256|PROSITE-ProRule:PRU00023};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT REPEAT 161..193
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 194..226
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REPEAT 227..259
FT /note="ANK"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00023"
FT REGION 1..98
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 122..166
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 277..316
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 386..476
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 518..553
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 568..660
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 698..741
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 793..1042
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1090..1169
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 1691..1765
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 22..94
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 122..146
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 147..166
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 394..434
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 455..474
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 525..553
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 584..622
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 623..637
FT /note="Basic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 638..660
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1090..1128
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1129..1169
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1703..1722
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 1733..1754
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 2032 AA; 231425 MW; 7782BB73976F3F8B CRC64;
MPKSGFAKPV QSENSDSDSN MVEKSYGRKS KDKIASYSKT PKIDRSDVGK EMKEKSSMKR
KLPFTISPSR NEERDSDTEK EGPEKKKTKK EAGNKKSTPV SILFGYPLSE RKQMALLMQM
TARDNSPDST PNHPSQTTPA QKKTPSSSSR QKDKVNKRNE RGETPLHMAA IRGDVKQVKE
LISLGANVNV KDFAGWTPLH EACNVGYYDV AKILIAAGAD VNTQGLDDDT PLHDSASSGH
RDIVKLLLRH GGNPFQANKH GERPVDVAET EELELLLKRE VPLSDDDESY TDSEEARSVN
PSSVDENIDS ETEKDSLICE SKQIVPSKAP LPSALDEYEF KDDDDEEINK MIDDRHILRK
ELRKENESEV EKNSLFAKQE KAFYPKSFKS KKQKPSRVLY SSSESSDEEI LQNKKCSTPS
SVPETSNSDI QTKKEYGISS EHKQKGKVKR KLKNQNKNKE NQELKQEKEG KENTRVTNLT
VNTAVDCSEK AREEGNFRKS FSPKDDTSLH LFHISTGKSP KHCCGLSEKQ STPLKQEHSK
TCLSPGSSEM SLQPDLVRYD NTESEFLPES SSVKSCKHKD KNKHQKDFHL EFGEKSNAKV
KDEDHSPTFE NSDCTLKKMD KEGKTLKKHK LKHKEREKEK HKKEIEGEKE KYKNRDGAKE
LQRSVEFDRE FWKENFFKSD ETEDLFLNME HESLTLEKKS KLEKSIKDDK STKEKHVSKE
RNFKEEREKV KKESEKSFKE EKIKDLKDER ENIPTDKETE FSSLGISASE ESVGFHSVEK
EIEIEKHIKE SKEKFEKRFQ TKEKDIEKAE RKNSEKEKKI KHEHKSEKDR LDLSECIDRI
KEKDKLYSHH TEKCHKESEK VKNFTTIKKT DDRDKSREKM DRKHDKEKPE KERHLAESKE
KHSVEKKTKQ SDSGDFARSE KSKSKEKDRE VDKKEKSRDS VNITNSKHFQ EERKSSIADS
NKAQHEKTLY LKEKTKDEPL KTPDGKEKDK KDIDRYKERD KHKDKIQLNS SLKLKLEVEK
PKPKSSPASK DTRPKEKRLV NDDLMQTSFE RMLSLKDLEI EQWHRKHKEK IKQKEKERLR
NRNCLELKVK DKEKTKHSLA EFKNKELTRS KSSELTDAYT KEKQSKDAIS NRSQSVDTKN
PVSLGKSSFV SENSLNRSPR SESEKLGLSS RSVSMISVAS SEDSCHTTVT TPRPPVEYDS
DFMLEGSDSQ MSFSQSPFLP VAKSPALHER ELDSLAELPE RIKASYTSRL PASHIRSASV
EDVKLVLSEG RPTVEVRRCS MPSAICEHTK QFQATSEESN QDGLALPREV CASPRPEASS
NVPERELSSA SNIHSSFAAS PAMSVNSKYT SADINVIKSS APVVTLVDSP IHLEPSNQVG
VIQNKAWEIP VDRLGPLSTS DFICSNSCTP DQDSSVQGFC NSENKILKEQ NIDFLPLHQT
ELPGNTCAQD AASFLPSQQP CSSHSQSLSD AESISKHMSL SYVTSQEPGI LQQKNAIQMI
NAVLDTDNES TKDRENTFVL ADVQKTDAFT PVYSESTVQE AAPNFEKANS LPVLPLEKDF
NGSDASSQPN THYALSKLLY KSSSSHEVEN STSDIQVISH EKEKLESVVL THLHVKCDSD
LCEINAGVPK GNLHEQDNPK HCSESLKCLL SIEDEESQQS TLSSLENHSQ PSAQPEMHKY
GHLVKVELEE SAEDDKTENQ IPQRMTRNKA NTVANQSKQI LASCPLLPDK DSESSSPRGR
IRLTEEDDPQ IHHPRKRKVS RVPQPVQVSP SLLQAKEKTQ QSLAAIVDSL KLDEIQPYSS
ERANPYFEYL HIRKKIEEKR KLLCSVIPQA PQYYDEYVTF NGSYLLDGNP LSKICIPTIT
PPPSLSDPLK ELFRQQEVVR MKLRLQHSIE REKLIVSNEQ EVLRVHYRAA RTLANQTLPF
SACTVLLDAE VYSVPLDAQS DDSKTSVRDR FNARQFMSWL QDVDDKFDKL KTCLLMRQQH
EAAALNAVQR LEWQLKLQEL DPATYKSISI YEIQEFYVPL VDVNDDFELT PI
//
