ID A0A287BP33_PIG Unreviewed; 731 AA.
AC A0A287BP33;
DT 22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT 22-NOV-2017, sequence version 1.
DT 27-MAR-2024, entry version 31.
DE SubName: Full=EMAP like 1 {ECO:0000313|Ensembl:ENSSSCP00000058184.1};
DE SubName: Full=Echinoderm microtubule-associated protein-like 1 isoform X1 {ECO:0000313|EMBL:HDA40375.1};
DE SubName: Full=Echinoderm microtubule-associated protein-like 1 isoform b {ECO:0000313|EMBL:HDA76694.1};
GN Name=EML1 {ECO:0000313|Ensembl:ENSSSCP00000058184.1,
GN ECO:0000313|VGNC:VGNC:87682};
OS Sus scrofa (Pig).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000058184.1, ECO:0000313|Proteomes:UP000008227};
RN [1] {ECO:0000313|Ensembl:ENSSSCP00000058184.1, ECO:0000313|Proteomes:UP000008227}
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000058184.1,
RC ECO:0000313|Proteomes:UP000008227};
RG Porcine genome sequencing project;
RL Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN [2] {ECO:0000313|EMBL:HDA40375.1}
RP NUCLEOTIDE SEQUENCE.
RX PubMed=30723633; DOI=.7717/peerj.6374;
RA Gilbert D.G.;
RT "Genes of the pig, Sus scrofa, reconstructed with EvidentialGene.";
RL PeerJ 7:E6374-E6374(2019).
RN [3] {ECO:0000313|Ensembl:ENSSSCP00000058184.1}
RP IDENTIFICATION.
RG Ensembl;
RL Submitted (NOV-2023) to UniProtKB.
CC -!- SUBCELLULAR LOCATION: Cytoplasm, cytoskeleton
CC {ECO:0000256|ARBA:ARBA00004245}.
CC -!- SIMILARITY: Belongs to the WD repeat EMAP family.
CC {ECO:0000256|ARBA:ARBA00006489}.
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DR EMBL; DQIR01084899; HDA40375.1; -; Transcribed_RNA.
DR EMBL; DQIR01121218; HDA76694.1; -; Transcribed_RNA.
DR EMBL; DQIR01129888; HDA85364.1; -; Transcribed_RNA.
DR EMBL; DQIR01132770; HDA88246.1; -; Transcribed_RNA.
DR PaxDb; 9823-ENSSSCP00000024697; -.
DR Ensembl; ENSSSCT00000065578.2; ENSSSCP00000058184.1; ENSSSCG00000027667.4.
DR VGNC; VGNC:87682; EML1.
DR eggNOG; KOG2106; Eukaryota.
DR GeneTree; ENSGT00940000153887; -.
DR Proteomes; UP000008227; Chromosome 7.
DR Bgee; ENSSSCG00000027667; Expressed in stomach and 40 other cell types or tissues.
DR GO; GO:0005856; C:cytoskeleton; IEA:UniProtKB-SubCell.
DR CDD; cd21947; TD_EMAP1; 1.
DR Gene3D; 2.130.10.10; YVTN repeat-like/Quinoprotein amine dehydrogenase; 2.
DR InterPro; IPR005108; HELP.
DR InterPro; IPR011047; Quinoprotein_ADH-like_supfam.
DR InterPro; IPR015943; WD40/YVTN_repeat-like_dom_sf.
DR InterPro; IPR001680; WD40_rpt.
DR PANTHER; PTHR13720:SF22; ECHINODERM MICROTUBULE-ASSOCIATED PROTEIN-LIKE 1; 1.
DR PANTHER; PTHR13720; WD-40 REPEAT PROTEIN; 1.
DR Pfam; PF03451; HELP; 1.
DR Pfam; PF00400; WD40; 4.
DR SMART; SM00320; WD40; 9.
DR SUPFAM; SSF50998; Quinoprotein alcohol dehydrogenase-like; 1.
DR PROSITE; PS50082; WD_REPEATS_2; 1.
PE 1: Evidence at protein level;
KW Coiled coil {ECO:0000256|SAM:Coils};
KW Proteomics identification {ECO:0007829|PeptideAtlas:A0A287BP33};
KW Reference proteome {ECO:0000313|Proteomes:UP000008227};
KW WD repeat {ECO:0000256|PROSITE-ProRule:PRU00221}.
FT DOMAIN 189..260
FT /note="HELP"
FT /evidence="ECO:0000259|Pfam:PF03451"
FT REPEAT 540..572
FT /note="WD"
FT /evidence="ECO:0000256|PROSITE-ProRule:PRU00221"
FT REGION 77..180
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 31..72
FT /evidence="ECO:0000256|SAM:Coils"
FT COMPBIAS 89..142
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 154..170
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 731 AA; 80169 MW; 5F7C72CB14CB5B93 CRC64;
MEDGFSSYSS LYDTSSLLQF CNDDSASAAS SMEVTDRIAS LEQRVQMQED DIQLLKSALA
DVVRRLNITE EQQAVLNRKG PTKARPLVQT LPLRTTVNNG TVLPKKPSGS LPSPSGARKE
TSVPATTKST IKRTSSSERV SPGGRRESYG DSKGNRNRTG STSSSSSGKK NSESKPKEPV
FSAEEGYVKM FLRGRPVTMY MPKDQVDSYN LEAKVELPTK RLKLEWVYGY RGRDCRNNLY
LLPTGETVYF IASVVVLYNV EEQLQRHYAG HNDDVKCLAV HPDRITIATG QVAGTSKDGK
QLPPHVRIWD SVTLNTLHVI GIGFFDRAVT CIAFSKSNGG SSLCAVDDSN DHVLSVWDWQ
KEERLADVKC SNEAVFAADF HPTDTNIIVT CGKSHLYFWT LEGSSLIKKQ GLFEKQEKPK
FVLCVTFSEN GDAITGDSSG NILVWGKGTN RISYAVQGAH EGGIFALCML RDGTLVSGGG
KDRKLISWNG NYQKLHKTEI PEQFGPIRTV AEGKGDVILI GTTRNFVLQG TLSGDFTPIT
QGHTDELWGL AIHASKPQFL TCGHDRHATL WDAVGHRPVW DKIIEDPAQS SGFHPSGSVV
AVGTLTGRWF VFDTETKDLV TVHTDGNEQL SVMRYSPDGN FLAIGSHDNC IYIYGVSDSG
RKYTRVGKCS GHSSFITHLD WSVNSQFLVS NSGDYEILYC EWLCRAGLGA GHSGTFTLRP
DGASCESPLP A
//
