ID   A0A287BPU8_PIG          Unreviewed;      1030 AA.
AC   A0A287BPU8;
DT   22-NOV-2017, integrated into UniProtKB/TrEMBL.
DT   14-DEC-2022, sequence version 3.
DT   27-MAR-2024, entry version 28.
DE   SubName: Full=Transport and golgi organization 6 homolog {ECO:0000313|Ensembl:ENSSSCP00000058643.3};
GN   Name=TANGO6 {ECO:0000313|Ensembl:ENSSSCP00000058643.3};
OS   Sus scrofa (Pig).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus.
OX   NCBI_TaxID=9823 {ECO:0000313|Ensembl:ENSSSCP00000058643.3, ECO:0000313|Proteomes:UP000008227};
RN   [1] {ECO:0000313|Ensembl:ENSSSCP00000058643.3, ECO:0000313|Proteomes:UP000008227}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Duroc {ECO:0000313|Ensembl:ENSSSCP00000058643.3,
RC   ECO:0000313|Proteomes:UP000008227};
RG   Porcine genome sequencing project;
RL   Submitted (NOV-2009) to the EMBL/GenBank/DDBJ databases.
RN   [2] {ECO:0000313|Ensembl:ENSSSCP00000058643.3}
RP   IDENTIFICATION.
RG   Ensembl;
RL   Submitted (NOV-2023) to UniProtKB.
CC   -!- SIMILARITY: Belongs to the Tango6 family.
CC       {ECO:0000256|ARBA:ARBA00005724}.
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DR   AlphaFoldDB; A0A287BPU8; -.
DR   STRING; 9823.ENSSSCP00000058643; -.
DR   Ensembl; ENSSSCT00000058839.3; ENSSSCP00000058643.3; ENSSSCG00000051585.2.
DR   GeneTree; ENSGT00390000010938; -.
DR   InParanoid; A0A287BPU8; -.
DR   Proteomes; UP000008227; Chromosome 6.
DR   Bgee; ENSSSCG00000051585; Expressed in oocyte and 43 other cell types or tissues.
DR   GO; GO:0009306; P:protein secretion; IBA:GO_Central.
DR   Gene3D; 1.25.10.10; Leucine-rich Repeat Variant; 1.
DR   InterPro; IPR011989; ARM-like.
DR   InterPro; IPR016024; ARM-type_fold.
DR   InterPro; IPR019451; Rtp1_C1.
DR   InterPro; IPR019414; Rtp1_C2.
DR   InterPro; IPR039600; TANGO6/Rtp1.
DR   PANTHER; PTHR20959; TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 FAMILY MEMBER; 1.
DR   PANTHER; PTHR20959:SF1; TRANSPORT AND GOLGI ORGANIZATION PROTEIN 6 HOMOLOG; 1.
DR   Pfam; PF10363; RTP1_C1; 1.
DR   Pfam; PF10304; RTP1_C2; 1.
DR   SUPFAM; SSF48371; ARM repeat; 1.
PE   3: Inferred from homology;
KW   Reference proteome {ECO:0000313|Proteomes:UP000008227}.
FT   DOMAIN          775..886
FT                   /note="RNA polymerase II assembly factor Rtp1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10363"
FT   DOMAIN          977..1010
FT                   /note="RNA polymerase II assembly factor Rtp1 C-terminal"
FT                   /evidence="ECO:0000259|Pfam:PF10304"
FT   REGION          700..749
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        705..728
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        729..743
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   1030 AA;  112803 MW;  19CED8D8C1613A60 CRC64;
     MAAARQVAGG RALETCGMER ILEALKLLLS PGGSGSSSLQ ITKHDVLLAT LKSNLSALED
     KLLKDPHWKE LKLLRDAVAN EAEWPRGSAD ITWAFTAQTL LLLLCLKETM MRLAAGFNPG
     KPNPRTPEAA PALSPDTLSV SQQKTVQSVL QFVVTLGVCP YLVPGVGVPL KCRTEFGAVV
     QDVVCLSAAP SAARRLYTSC SVLLSVAQNA ALGSLIFCRH FGDIAAGLCQ LGFCPTERKA
     LNPEEEVLTE EERALSREAL RDILDQVYQP LAVRELLTLQ GGAPQSCTDG KTQVRCRAPA
     WLRRLCGQLL SERLMRPSGV QAVVRGILEG AGAGAAGGSD AEAIAADWKK CDVIAKILSS
     CPQQSLSPED YYRDICPQIL DLFHFQDKLT ARQFQRVATT TFITMSRERP QLAAKYLLQP
     VLAPLHRCLN TAEIPKSDMV PGTVLVTEEE LSRCIEDVFK VYVVGNDPVT VLVDSLLPVL
     GVLFSLYCFT KQSVSHTRSL CQEILLWILG KLERKKALAS LKGFAGLDRS VPSLHSLCHF
     KAAAQGGIMI TIKEAICDED EDEALYQKVS SEQCQVEHLG DLLSHCQECG LAGDFFILCL
     KVVDFVAALQ RACASLAHQA ESSVESQTLS MSMGLVAVML GGAVQLKSSD FAILKQLVPL
     LEKVSTTYPD PVIQELAVDL RITISTHGAF TTEAVSVAAQ STLSKEDPEG KREEQQQASH
     ERHCDMSPSH LKPQQSHDMS RQTGLKPNPP LVPPVVREPS ITTNQKSGSL TAEQLQEALL
     SAYDPQIPTR AAALRTLSRW VEQREPKALE VQEKLLKVFL ENLEHEDTFV YLSAIQGAAL
     LSDVYPEKIL CGLLTQYDAG KDKHTAETRM KVGEVLMRTV RALGDMVSKY REPLIHTFLR
     GARDPDGAHR ASSLSNLGEL CQRLDFLLGS VVHEVTACLI AVAKTDPEVQ VRRAAIHVIV
     LLLRGLSQKA TEVLKDVLRD LYHLLKHVVR LEPDDVAKLH AQLALEELDE IMRNFLFPPQ
     KLEKKIVVLP
//